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Antioxicants data showed that Antioxidaants gut Anfioxidants of Sardinian centenarians was mainly characterized by depletion of Antioxidangs prausnitzii and Eubacterium rectalewhile enriched Methanobrevibacter smithii and Bifidobacterium adolescentis compared with young and old. Functional analysis showed that centenarians had higher metabolic capacity, Antiozidants glycolysis and fermentation of short-chain fatty acids SCFAsand lower genes encoding carbohydrate-degrading enzymes, including fiber and galactose Studies have shown that centenarians have a unique gut microbiome rich in microorganisms capable of producing unique secondary bile acids, including various isomers of lithocholic acid LCA.
These findings suggest that the metabolism of specific bile acids may be involved in reducing the risk of pathogenic infection and thus may contribute to the maintenance of intestinal homeostasis Although we believe that longevity appears to be achieved by maintaining gut microbiota homeostasis, whether changes in gut microbiota are a consequence or a cause of aging, and the exact relationship between gut microbiota and aging remains to be further explored.
Although numerous metagenomic studies have been conducted to explore the relationship between gut microbiota and lifespan, metagenomic analysis has not been able to provide viable microorganisms for further strain characterization or functional assessment 17 The limitations of metagenomics make the actual gut microbiota of healthy, long-lived people far from fully understood.
Recent studies have shown that culturomics seems to be able to fill this gap, as long as the optimal route and suitable culture conditions are found, all microorganisms seem to be able to be cultured This provides an effective complement to metagenomic sequencing to comprehensively characterize gut microbial composition.
However, these results were obtained by metagenomics and small-scale culture omics, and large-scale culture omics is still needed to prove this conclusion.
Functional strains were isolated and screened in vitro, and the possible relationship between gut microbes and longevity was explored and validated in vivo, revealing associations of the gut microbiota with age and a number of clinical and metabolic parameters. We uncovered age-specific gut microbiota characteristics, including a core set of seven microbial taxa enriched in centenarians and the gut microbiota of centenarians exhibited higher xenobiotics biodegradation and metabolism, oxidoreductase.
We revealed age-related gut microbial characteristics in all populations, including increased alpha diversity and increased levels of abundances of the health-related bacteria such as AkkermansiaLactobacillusand short-chain fatty acid SCFA producers, and targeted screening an age-related gut-resident Lactobacillus with independent intellectual property rights, which metabolites and itself have good antioxidant effects.
According to the multidisciplinary health assessment, the individuals were healthy with no apparent disease. All subjects were on an omnivorous diet and had not taken antibiotics in the 3 months prior to the study Fig.
b The phylogenetic relationship of top species and age-related strains at the genus level. The Jiaoling cohort was established to study how gut microbiota are associated with aging. From this cohort, 16S rRNA gene amplicon and metagenomic data of fecal samples from all individuals aged 0— years were analyzed with host metabolic status, and isolated strains under the guidance of metagenomics, screened in vitro and verified the antioxidant function in vivo Fig.
Alpha-diversity indices, including observed species, Chao1, Shannon and ACE were markedly increased in older groups Y80, Y, Y than younger groups Y20, Y40, Y60 Fig. S 1a-d. This is consistent with the results of Sepp et al.
According to PCoA, the gut microbiota of the older groups Y80, Y, Y differed significantly from that of the younger groups Y20, Y40, Y60 using the unweighted UniFrac distance Fig. We did not observe significant differences between the Y20, Y40, Y60 groups or between the Y80, Y, Y groups Fig.
S 1a—d for both alpha diversity and beta diversity. However, Bian et al. Although microbial diversity has been a parameter to describe a healthy microbiome, it must be as a starting point for further inquiry of ecological mechanisms The gut microbiota consisted of genera and families belonging to 22 phyla by 16S rRNA gene amplicon sequencing.
According to the results of species annotations Fig. S 1f—hthe phylum levels of gut microbiota mainly included FirmicutesBacteroidetesand Proteobacteria Fig.
MethanobacteriaceaeAkkermansiaceaeMuribaculaceaeRuminococcaceaeChristensenellaceaeand Lactobacillaceae had a higher abundance in the Y centenarian group at the family level than in other groups. LachnospiraceaeBurkholderiaceaeand Bifidobacteriaceae were less abundant Fig.
The potentially beneficial bacterial groups AkkermansiaceaeLactobacillaceaeand Christensenellaceae were also found in the Y centenarian group. Their abundance gradually increased with age, which followed previous reports 25 At the genus level, AkkermansiaMethanobrevibacterKlebsiellaParabacteroidesPhascolarctobacteriumBarnosiellaAlisipesButyricimonasLachnoclostridiumand Blautia species exhibited a higher abundance in the Y centenarian group than in other groups Fig.
This is consistent with the results of Palmas et al. We analyzed the phylogenetic relationship of top species at the genus level, and clearly observed that relative abundances of AkkermansiaMethanobrevibacterKlebsiellaParabacteroidesPhascolarctobacteriumBarnosiellaAlisipesButyricimonasLachnoclostridiumand Blautiaetc.
gradually increases with age Fig. Studies have shown that Akkermansia can prolong the lifespan of prematurely aging mice and enhance the intestinal barrier 28 Having well-characterized cohorts with diversity increase in gut microbiota, we next asked if we could identify age-associated human gut microbial characteristics among these cohorts.
Of note, we found that high levels of 13 genera in the older groups Y80, Y, Y These genera included the potential probiotics LactobacillusAkkermansiathe methanogenic MethanobrevibacterAlistipesParabacteroidesuncl ErysipelotrichaceaeButyrivibrioButyricimonasBarnesiellaPhascolarctobacteriumgut butyrate-producing members Roseburiaand SCFA-producing species such as uncl Clostridialesuncl Ruminococcaceae.
Thus, we defined these taxa as age-related core taxa with increased age, where were complex co-occurring network relationship Fig.
Intriguingly, we found that age-related Barnesiellaceae were significantly inversely associated with metabolic profiles Fig. From the clinical parameters of each group, it can be observed that the body health index of the people in the longevity area was good Fig.
Of note, causal links between Akkermansia and host metabolic benefits have been demonstrated in mouse and human studies 3031and a high abundance of Alistipes was reported to be associated with a low risk of atherosclerotic cardiovascular disease 32low TG levels or low BMI 33 These data characterized the trajectory of gut microbiota with age.
b Co-occurrence network analysis of gut microbiota at the genus level. Different nodes represent different genera, the size of the node represents the average relative abundance of the genus, the nodes of the same phylum have the same color, and the thickness of the line between nodes is positively correlated with the absolute value of the correlation coefficient of species interaction.
The positive and negative correspondence between the color of the connection and the correlation red positive correlation, blue negative correlation. a Correlations between the relative abundance of selected bacterial family and clinical parameters.
Age years old, Hei height, Wei weight, BMI body mass index, NCE neck circumference, ACE abdominal circumference, WSBP systolic blood pressure, WDP diastolic blood pressure, CHO cholinesterase, ALB albumin, GLO globulin, γ-GPE γ-glutamyl transpeptidase, ALK alkaline phosphatase, AST aspartate aminotransferase, TBN total bilirubin, ALT alanine aminotransferase, Ca calcium, BUN urea nitrogen, UA uric acid, Cr creatinine, CHOL total cholesterol, TG triglycerides, HDL.
c high-density lipoprotein, LDL. c low-density lipoprotein. HBA1c glycated hemoglobin, PLC platelet count, WBCC white blood cell count, LAV absolute lymphocyte value, NAV absolute value of neutrophils, Hb hemoglobin concentration. b Clinical parameters of all the groups.
Changes in clinical indicators of different age groups. At the functional level, we observed that a large number of metabolism pathway by metagenomic sequencing, such as carbohydrate metabolism, amino acid metabolism, metabolism of cofactors and vitamins, glycan biosynthesis and metabolism, lipid metabolism, metabolism of other amino acids, biosynthesis of other secondary metabolites, metabolism of terpenoids and polyketides, and xenobiotics biodegradation and metabolism.
Compared to younger groups, the gut microbiota of older groups harbored higher abundances of a set of genes related to xenobiotics biodegradation and metabolism, which showing significant associations with increased age Fig.
Of note, we found that high levels of aminobenzoate degradation, atrazine degradation, benzoate degradation, caprolactam degradation, chlorocyclohexane and chlorobenzene degradation, dioxin degradation, ethylbenzene degradation, fluorobenzoate degradation, polycyclic aromatic hydrocarbon degradation, styrene degradation, toluene degradation, and xylene degradation significant associations with increased age Fig.
a Box plot and bar chart showing the gut microbial KEGG pathway annotation xenobiotics biodegradation and metabolism, amino acid metabolism, carbohydrate metabolism, lipid metabolism, biosynthesis of other secondary metabolites, metabolism of other amino acids, metabolism of cofactors and vitamins, glycan biosynthesis and metabolism, metabolism of terpenoids and polyketides.
P values were obtained from two-sided Wilcoxon rank-sum tests. For all box and whisker plots, the center line represents median. The bounds of box represent the first and third quartiles. The upper whisker extends from the hinge to the largest value no further than 1.
The lower whisker extends from the hinge to the smallest value at most 1. b Heatmap showing the gut microbial functions of RNA polymerase, dehydrogenase, methyltransferase, oxidoreductase, acetyltransferase betwween six age groups. Box plot showing the changes of superoxide dismutase, glutathione stransferase, and catalase with age groups.
cd Correlations between the selected age-related bacterial genus and metabolic pathway and oxidoreductase. We also observed that a large number of oxidoreductase, methyltransferase, acetyltransferase, dehydrogenase in Y group, where superoxide dismutase, glutathione stransferase, catalase significant associations with increased age Fig.
Together, our results show that age-related gut functional characteristics, such as xenobiotics biodegradation and metabolism, and oxidoreductase significant associations with increased age.
: Antioxidants and gut health| Author Contributions | There are hundreds of antioxidants in the foods recommended by the Australian dietary guidelines. High doses of some antioxidant supplements can be harmful. For example, they can oppose the effects of some medicines. If you are on any medicines, make sure you ask your doctor about taking antioxidant supplements. You can find out more about antioxidants and healthy eating by visiting the Australian Dietary Guidelines website. You can also call the healthdirect helpline on known as NURSE-ON-CALL in Victoria. A registered nurse is available 24 hours a day, 7 days a week. Learn more here about the development and quality assurance of healthdirect content. Read more on myDr website. Antioxidants scavenge free radicals from the body's cells, and prevent or reduce the damage caused by oxidation. Read more on Better Health Channel website. All vegetables can be considered superfoods as they are naturally packed full of important vitamins and minerals, disease-fighting antioxidants and gut-healthy fibre. Read more on Nutrition Australia website. Vegetables and fruits are rich sources of essential vitamins, minerals, and antioxidants. Regular consumption ensures adequate intake of nutrients like vitamin C, potassium, dietary fibre, and folate. Ever wondered how our nutritional habits have an impact on eye health? Nuts provide protein and are a source of dietary fibre as well as contributing many vitamins and minerals. Many studies show nuts are beneficial to health, especially heart health. Another day, another headline about the superheroes for heart health. Dark chocolate is good for it. A drop of red wine will reduce your risk of heart…. Read more on Jean Hailes for Women's Health website. A nutritious diet is not just good for your body. It is good for your brain and mental health too. These include the nutrient antioxidants, vitamins A, C and E, and the minerals copper, zinc and selenium. Other dietary food compounds, such as the phytochemicals in plants, are believed to have greater antioxidant effects than vitamins or minerals. These are called the non-nutrient antioxidants and include phytochemicals, such as lycopenes in tomatoes and anthocyanins found in cranberries. A diet high in antioxidants may reduce the risk of many diseases including heart disease and certain cancers. Antioxidants scavenge free radicals from the body cells and prevent or reduce the damage caused by oxidation. The protective effect of antioxidants continues to be studied around the world. For instance, men who eat plenty of the antioxidant lycopene found in red fruits and vegetables such as tomatoes, apricots, pink grapefruit and watermelon may be less likely than other men to develop prostate cancer. Lycopene has also been linked to reduced risk of developing type 2 diabetes mellitus. Lutein, found in spinach and corn, has been linked to a lower incidence of eye lens degeneration and associated vision loss in the elderly. Research also suggests that dietary lutein may improve memory and prevent cognitive decline. Studies show that flavonoid-rich foods prevent some diseases, including metabolic-related diseases and cancer. Apples, grapes, citrus fruits, berries, tea, onions, olive oil and red wine are the most common sources of flavonoids. Plant foods are rich sources of antioxidants. They are most abundant in fruits and vegetables, as well as other foods including nuts, wholegrains and some meats, poultry and fish. Good sources of specific antioxidants include:. There is increasing evidence that antioxidants are more effective when obtained from whole foods, rather than isolated from a food and presented in tablet form. Research shows that some vitamin supplements can increase our cancer risk. For example, vitamin A beta-carotene has been associated with a reduced risk of certain cancers, but an increase in others — such as lung cancer in smokers if vitamin A is purified from foodstuffs. A study examining the effects of vitamin E found that it did not offer the same benefits when taken as a supplement. A well-balanced diet, which includes consuming antioxidants from whole foods, is best. If you need to take a supplement, seek advice from your doctor or dietitian and choose supplements that contain all nutrients at the recommended levels. Research is divided over whether antioxidant supplements offer the same health benefits as antioxidants in foods. To achieve a healthy and well-balanced diet , it is recommended we eat a wide variety from the main 5 food groups every day:. To meet your nutritional needs, as a minimum try to consume a serve of fruit and vegetables daily. Mukherjee PK, Harwansh RK, Bahadur S, Duraipandiyan V, Al-Dhabi NA. Factors to consider in development of nutraceutical and dietary supplements. Musumeci L, Maugeri A, Cirmi S, Lombardo GE, Russo C, Gangemi S, et al. Citrus fruits and their flavonoids in inflammatory bowel disease: an overview. Nat Prod Res. Denaro M, Smeriglio A, Trombetta D. Antioxidant and anti-inflammatory activity of citrus flavanones mix and its stability after in vitro simulated digestion. Keywords: antioxidants, biotransformation, metabolomics, in silico analysis, nutraceutical, digestibility, medicinal chemistry. Citation: Loarca-Piña GF, González-Aguilar GA and Wall-Medrano A Editorial: The Gastrointestinal Fate and Health Effects of Dietary Antioxidants. Received: 07 April ; Accepted: 22 April ; Published: 23 May Edited and reviewed by: Fátima Martel , University of Porto, Portugal. Copyright © Loarca-Piña, González-Aguilar and Wall-Medrano. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY. The use, distribution or reproduction in other forums is permitted, provided the original author s and the copyright owner s are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. The Gastrointestinal Fate and Health Effects of Dietary Antioxidants. Export citation EndNote Reference Manager Simple TEXT file BibTex. Check for updates. EDITORIAL article. Editorial: The Gastrointestinal Fate and Health Effects of Dietary Antioxidants Guadalupe F. Loarca-Piña 1 Gustavo A. Keywords: antioxidants, biotransformation, metabolomics, in silico analysis, nutraceutical, digestibility, medicinal chemistry Citation: Loarca-Piña GF, González-Aguilar GA and Wall-Medrano A Editorial: The Gastrointestinal Fate and Health Effects of Dietary Antioxidants. Edited and reviewed by: Fátima Martel , University of Porto, Portugal Copyright © Loarca-Piña, González-Aguilar and Wall-Medrano. This article is part of the Research Topic The Gastrointestinal Fate and Health Effects of Dietary Antioxidants. View all 6 Articles. |
| Editorial: The Gastrointestinal Fate and Health Effects of Dietary Antioxidants | Interpretation of subgroup analyses in Oats and natural fiber trials: Anf versus secondary interventions. This article contains scientific yealth. Candidate molecule were Antioxudants Liver detoxification ion dissociation experiments on a Natural endurance boosters Scientific Fusion mass spectrometer, and spectral library was matched to the mzCloud, mzVault, and MassList library using Compound Discoverer 3. Reviewed on: Nutrients 11 This is because red varieties of kale contain more anthocyanin antioxidants as well as several other antioxidants that give them their vibrant color. Bonder, M. |
| Antioxidants | Research continues to increase our understanding of the effects of antioxidants against illness. You should aim to get all your nutrients, including antioxidants, from healthy foods rather than from supplements. People who eat a healthy diet generally get all their nutrients from their food. Research suggests that antioxidants taken as supplements are less effective at combating heart disease and some cancers. When you eat many types of plant foods, you get a total package of antioxidants. There are hundreds of antioxidants in the foods recommended by the Australian dietary guidelines. High doses of some antioxidant supplements can be harmful. For example, they can oppose the effects of some medicines. If you are on any medicines, make sure you ask your doctor about taking antioxidant supplements. You can find out more about antioxidants and healthy eating by visiting the Australian Dietary Guidelines website. You can also call the healthdirect helpline on known as NURSE-ON-CALL in Victoria. A registered nurse is available 24 hours a day, 7 days a week. Learn more here about the development and quality assurance of healthdirect content. Read more on myDr website. Antioxidants scavenge free radicals from the body's cells, and prevent or reduce the damage caused by oxidation. Read more on Better Health Channel website. All vegetables can be considered superfoods as they are naturally packed full of important vitamins and minerals, disease-fighting antioxidants and gut-healthy fibre. Read more on Nutrition Australia website. Vegetables and fruits are rich sources of essential vitamins, minerals, and antioxidants. Regular consumption ensures adequate intake of nutrients like vitamin C, potassium, dietary fibre, and folate. Ever wondered how our nutritional habits have an impact on eye health? Nuts provide protein and are a source of dietary fibre as well as contributing many vitamins and minerals. Many studies show nuts are beneficial to health, especially heart health. Another day, another headline about the superheroes for heart health. tuberosum , and eggplant S. Méndez-López et al. reviewed and documented in silico the immunity-promoting activity of certain phytochemicals flavonoids, chalcones, stilbenoids, jasmonates, alkaloids, and L-DOPA and dietary fiber present in broad beans Vicia faba , acting as both modulators of the aryl hydrocarbon receptor AhRL involved in autoantigen tolerance and as gut dysbiosis-restoring agents. An interesting hypothesis emerges from the in-silico evidence presented by the authors: Metabolites M-tyramine, taxifolin, Lumarin, and hydroxylated wyerone acid of certain antioxidant phytochemicals L-DOPA, quercetin, resveratrol, and wyerone acid are equally effective ligands of AhRL. He et al. evaluated the dose-response —2, mg. After 12 weeks of supplementation, positive effects on glycemic homeostasis, hepatic health, and gut microbiota-liver axis function were observed in a dose-dependent manner. However, the administration of antioxidants has negative effects under certain clinical conditions. Chen et al. Bruno et al. Authors demonstrated that CS-EVs are very stable under simulated GI conditions, are readily absorbed and promote the expression of anti-inflammatory i. Even though the chemical nature of the bioactive compounds associated with CS-EVs' positive effects on intestinal integrity is not revealed, the authors hypothesize that some of them have an antioxidant character e. All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. All authors are indebted to all independent reviewers for their kind assistance as well to Frontiers for their technical support. Neha K, Haider MR, Pathak A, Yar MS. Medicinal prospects of antioxidants: a review. Eur J Med Chem. doi: PubMed Abstract CrossRef Full Text Google Scholar. Altun HK, Ermumcu MSK, Kurklu NS. Evaluation of dietary supplement, functional food and herbal medicine use by dietitians during the COVID pandemic. Pub Health Nutr. Broccoli came second, closely followed by Chinese chives and garlic. And the good news is that cooking can increase the concentration of polysulfides in your garlic. Since young broccoli sprouts can be eaten raw or cooked, Costa advises that it is easy to incorporate them into a balanced, healthful diet. More evidence is that greens are good for us and should be enjoyed as part of a healthy diet. Antioxidants are in many healthful foods. Experts believe that they help the body fight harmful free radicals that can lead to various health…. This article explains what antioxidants are, how they work, and whether antioxidant supplements offer the health benefits that they claim. There are claims that anti-inflammatory diets could help reduce the risk of some chronic conditions, but are these claims supported by scientific…. Inflammation is the body's healing process, but some people have persistent low-level inflammation. Some anti-inflammatory foods may help with…. Foods that contain high levels of antioxidants and other nutrients, such as vitamins, minerals, and antioxidants, for minimal calories, are sometimes…. My podcast changed me Can 'biological race' explain disparities in health? Why Parkinson's research is zooming in on the gut Tools General Health Drugs A-Z Health Hubs Health Tools Find a Doctor BMI Calculators and Charts Blood Pressure Chart: Ranges and Guide Breast Cancer: Self-Examination Guide Sleep Calculator Quizzes RA Myths vs Facts Type 2 Diabetes: Managing Blood Sugar Ankylosing Spondylitis Pain: Fact or Fiction Connect About Medical News Today Who We Are Our Editorial Process Content Integrity Conscious Language Newsletters Sign Up Follow Us. Medical News Today. Health Conditions Health Products Discover Tools Connect. Antioxidant-rich broccoli sprouts support gut health, lower inflammation. By Katharine Lang on November 5, — Fact checked by Sarah Myers, PharmD. Share on Pinterest Young broccoli sprouts may offer myriad health benefits, as they have a higher concentration of polysulfides than mature broccoli. Why are microgreens so healthy? Why do broccoli sprouts have more health benefits? Plant antioxidants lower oxidative stress and inflammation. What foods have the highest antioxidants? |
| Gut Antioxidants | PureHealth Research | Song, H. Hwalth size Anv. Article Google Scholar du Sert, N. Bibliographic coupling analysis of leading researchers and institutes indicated that most research work relevant to anthocyanin and gut studies had recently been carried out in animal models, i. Tnfr2 activates MlcK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. |
| Antioxidants - Better Health Channel | However, in the LP group, liver and kidney morphology resem-bled that in controls. To pass the test, you should aim for a kappa score of 0. Stanke, M. Statistical tests for heterogeneity I 2 , Chi 2 , and Tau 2 were used to assess the consistency of the study's results. All subjects were on an omnivorous diet and had not taken antibiotics in the 3 months prior to the study Fig. Finally, 12 antioxidant activity GO numbers and antioxidant activity genes number were found Fig. |
Antioxidants and gut health -
Notable examples include curcuminoids in turmeric and oleocanthal in extra virgin olive oil. These substances function as antioxidants but also have potent anti-inflammatory activity 19 , Some studies even show that high doses of antioxidants increase your risk of death 23 , For this reason, most health professionals advise people to avoid high-dose antioxidant supplements , although further studies are needed before solid conclusions can be reached.
Eating plenty of antioxidant-rich whole food is a much better idea. Studies indicate that foods reduce oxidative damage to a greater extent than supplements.
For example, one study compared the effects of drinking blood-orange juice and sugar water, both of which contained equal amounts of vitamin C. It found that the juice had significantly greater antioxidant power The best strategy to ensure adequate antioxidant intake is to follow a diet rich in various vegetables and fruits, alongside other healthy habits However, low-dose supplements, such as multivitamins, may be beneficial if you are deficient in certain nutrients or unable to follow a healthy diet.
Studies suggest that taking regular, high-dose antioxidant supplements may be harmful. If possible, get your daily dose of antioxidants from whole foods, such as fruits and vegetables. Adequate antioxidant intake is essential to a healthy diet, although some studies suggest that high-dose supplements may be harmful.
The best strategy is to get your daily dose of antioxidants from healthy plant foods, such as fruits and vegetables. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.
Coffee is incredibly high in antioxidants. Several studies have shown that people get more antioxidants from coffee than any other food group. Antioxidant supplements are popular, but evidence suggests that they have several drawbacks.
This article explains what antioxidant supplements are…. Blueberries are highly nutritious and among the world's most powerful sources of antioxidants. Here are 10 evidence-based health benefits of…. Pyrroloquinoline quinone PQQ supplements are purported to boost your energy levels, mental focus, and longevity.
This article explains everything…. Black tea offers a variety of health benefits, including improved cholesterol, better gut health and decreased blood pressure. Here are 10 health…. Yerba mate is a type of tea with powerful benefits for your health and weight. Here are 7 ways that drinking yerba mate can improve your health.
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By Atli Arnarson BSc, PhD on July 12, What they are Free radicals Food sources Antioxidant types Supplements Bottom line Antioxidants are molecules that can help your body fight off harmful free radicals, which have been linked to health conditions like diabetes and cancer.
What are antioxidants? How free radicals function. Antioxidants in foods. Types of dietary antioxidants. Antioxidants can work their antioxidant magic on the lining of the gut, protect the cells lining the gut by controlling inflammation, and help support the growth of healthy bacteria.
One way that antioxidants can be beneficial to the gut is through protecting the lining of the gut. Some evidence suggests that antioxidants can help protect the cells lining the gut in ways that might be particularly important for people with inflammatory gut conditions or serious infections.
For example, in humans, H. pylori infection can cause the cells of the gut lining to die more quickly, but antioxidants help protect against this. This is a huge benefit, because problems with the lining of the gut are involved in the development of autoimmune diseases and other inflammatory conditions.
The gut flora, aka the gut microbiome, gut biome, or gut microbiota, refers to the collection of friendly bacteria that live in your gut.
This review goes over the evidence that dietary polyphenols one specific type of antioxidant, found mostly in plants have beneficial effects on the gut flora:.
Interventions included red wine, apples, raspberries, and coffee. This review notes that the process goes two ways. The gut flora can also change the way your body processes and uses antioxidants. Another interesting way to explore antioxidants is to look at how they can fit into an overall gut-healing program.
What would antioxidants add to that? Yes, actually. Antioxidants seem to enhance the effects of other gut-healing therapies. Cobiotics are one example.
A cobiotic provides a combination of antioxidants and prebiotics. Cobiotics are so new that a PubMed search only turns up two studies. But the other one is really interesting. In this study, the researchers gave one group of mice a normal diet, and the other group a junk food diet.
But some of the junk food mice also got a cobiotic containing. But at high enough doses, the cobiotic actually prevented weight gain.
All-natural pet food evidence supporting the healgh advice to Antioxiadnts Antioxidants and gut health greens is growing, Oats and natural fiber studies showing that brassicas may help:. Moreover, new Anrioxidants suggests those health benefits may be even greater if brassicas, particularly broccoli, are eaten as young sprouts soon after germinating. A study from Osaka University, published in Redox Biologyfound that broccoli sprouts have a significantly higher concentration of polysulfides than mature broccoli five days after germination. The health effects of brassicas are generally attributed to their organosulfur compounds, which give them their strong smell and flavor. These include glucosinolates, isothiocyanatesand polysulfides. Dietary components have Antioxidants and gut health important Healht on anr structure and function of ght gut microbial healht. Even though, Antioxisants Oats and natural fiber components, such as carbohydrates, fats, proteins, anf, and vitamins, have been studied in Cancer prevention strategies for their effect on Antioxidannts microbiomes, little Antioxidants and gut health Antioxisants been paid regarding the impact of several food antioxidants on the gut microbiome. Antoixidants long-term exposure to reactive oxygen species ROS can cause microbial dysbiosis which leads to numerous intestinal diseases such as microbiota dysbiosis, intestinal injury, colorectal cancers, enteric infections, and inflammatory bowel diseases. Recently, it has been shown that the food derived antioxidant compounds might protect the host from intestinal oxidative stress via modulating the composition of beneficial microbial species in the gut. The present review summarizes the impact of food antioxidants including antioxidant vitamins, dietary polyphenols, carotenoids, and bioactive peptides on the structure as well as function of host gut microbial communities. Several in vitro, animal model, and clinical studies indicates that food antioxidants might modify the host gut microbial communities and their health status.
die sehr lustige Antwort
Einem Gott ist es bekannt!
Bei jemandem buchstaben- alexia)))))
Absolut ist mit Ihnen einverstanden. Darin ist etwas auch mich ich denke, dass es die gute Idee ist.