Pycnogenol and hormonal balance -
Vascular Aging across the Menopause Transition in Healthy Women. Adv Vasc Med. Cesarone MR, Belcaro G, Scipione C, Scipione V, Dugall M, Hu S, et al. Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox R. Bottari A, Belcaro G, Ledda A, Cesarone MR, Vinciguerra G, Di Renzo A, et al.
Lady Prelox R improves sexual function in post-menopausal women. Stanislavov R, Rohdewald P. PACR Pine Bark Extract, L Arginine, L Citrulline, Rose Hip Extract Improves Emotional, Physical Health and Sexual Function in Peri-Menopausal Women.
Kim YJ, Kang KS, Yokozawa T. The anti-melanogenic effect of pycnogenol by its anti-oxidative actions. Food Chem Toxicol. Ni Z, Mu Y, Gulati O. Treatment of melasma with Pycnogenol. Phytother Res. Grether-Beck S, Marini A, Jaenicke T, Krutmann J. French Maritime Pine Bark Extract Pycnogenol R Effects on Human Skin: Clinical and Molecular Evidence.
Skin Pharmacol Physiol. Saliou C, Rimbach G, Moini H, McLaughlin L, Hosseini S, Lee J, et al. Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in keratinocytes are modulated by a French maritime pine bark extract.
Free Radic Biol Med. Marini A, Grether-Beck S, Jaenicke T, Weber M, Burki C, Formann P, et al. Pycnogenol R effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women. Grimm T, Chovanova Z, Muchova J, Sumegova K, Liptakova A, Durackova Z, et al.
Inhibition of NF-kappaB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract Pycnogenol. J Inflamm Lond. Grimm T, Schafer A, Hogger P. Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract pycnogenol.
Belcaro G, Cesarone MR, Errichi BM, Ledda A, Di Renzo A, Stuard S, et al. Diabetic ulcers: microcirculatory improvement and faster healing with pycnogenol.
Clin Appl Thromb Hemost. Neogi T, Zhang Y. Epidemiology of osteoarthritis. Rheum Dis Clin North Am. Belcaro G, Cesarone MR, Errichi S, Zulli C, Errichi BM, Vinciguerra G, et al.
Variations in C-reactive protein, plasma free radicals and fibrinogen values in patients with osteoarthritis treated with Pycnogenol.
Redox Rep. Farid R, Mirfeizi Z, Mirheidari M, Rezaieyazdi Z, Mansouri H, Esmaelli H, et al. Pycnogenol supplementation reduces pain and stiffness and improves physical function in adults with knee osteoarthritis.
Nutrition Research. Cisar P, Jany R, Waczulikova I, Sumegova K, Muchova J, Vojtassak J, et al. Effect of pine bark extract Pycnogenol on symptoms of knee osteoarthritis. Treatment of osteoarthritis with Pycnogenol.
The SVOS San Valentino Osteo-arthrosis Study. Evaluation of signs, symptoms, physical performance and vascular aspects. Glyn-Jones S, Palmer AJR, Agricola R, Price AJ, Vincent TL, Weinans H, et al. The Lancet. Schafer A, Chovanova Z, Muchova J, Sumegova K, Liptakova A, Durackova Z, et al.
Inhibition of COX-1 and COX-2 activity by plasma of human volunteers after ingestion of French maritime pine bark extract Pycnogenol. Biomed Pharmacother. Canali R, Comitato R, Schonlau F, Virgili F. The anti-inflammatory pharmacology of Pycnogenol in humans involves COX-2 and 5-LOX mRNA expression in leukocytes.
Int Immunopharmacol. Vaginal dryness improved after just eight weeks of supplementation with Pycnogenol in a study of perimenopausal women who took 30 mg of the supplement in a three-month study.
A healthy immune system and immune response are critical for overall health and navigating menopause, especially the impact of inflammation on the body. Experts have found that Pycnogenol has an ability to prevent inflammation induced by immune system response, which is what occurs in individuals who have asthma, allergies, arthritis, or some autoimmune conditions.
Pycnogenol does this by inhibiting the activity of immune cells that trigger inflammation. One example of this effect of Pycnogenol was seen in a study in which healthy volunteers had blood samples taken before and after taking mg Pycnogenol daily for five days. The researchers found that the supplement showed anti-inflammatory properties by inhibiting pro-inflammatory activity.
Aunt flo has left the building, does it feel like your old self went with her? Let us help you find yourself again. your privacy is important to us. Challenges with memory, concentration, focus, attention, and brain fog are a significant concern among many women in the menopause years.
In fact, many women are afraid that the difficulties they experience during this period of life will become permanent or get worse. The good news is that in most cases, the brain fog and other cognitive function challenges seem to be temporary.
Once hormone fluctuations have settled over time and symptoms related to them have resolved, cognitive health improves. For eight weeks, 40 participants took mg per day of Pycnogenol and 39 served as controls. In a Frontiers of Pharmacology study published in that reviewed the literature on Pycnogenol and its impact on cognitive function in aging, the authors noted several findings.
Another study involved 60 healthy professionals who took either 50 mg Pycnogenol three times a day for 12 weeks while also adhering to a healthy lifestyle that included daily exercise, adequate sleep, and a nutritious diet, or who simply followed the healthy lifestyle.
The authors found that those who took the supplement showed a significant improvement in mental performance, attention, memory, and mood when compared with the lifestyle-only group. The Pycnogenol group also had a marked decline in oxidative stress , a factor that plays a big role in brain health and function.
Further evidence of the ability of Pycnogenol to support cognitive function comes from a review of more than research studies involving animals and humans. Dry, fragile, red, itchy, irritated, wrinkled, sagging—all of these descriptions and more can apply to menopausal skin.
Along with dropping estrogen and progesterone levels, women experience declines in the proteins elastin and collagen, which are critical for promoting and maintaining skin health.
Years of free radical damage from sunlight, environmental toxins, and smoking takes its toll as well. Pycnogenol can play several roles in menopausal skin health. As an antioxidant, it can neutralize free radicals before they do further damage.
The supplement also may support the synthesis of collagen and hinder the breakdown of elastin. In a study of 20 postmenopausal women, use of Pycnogenol for 12 weeks was evaluated non-invasively and by taking biopsies.
Use of the supplement resulted in a significant improvement in hydration and elasticity of the skin as well as an increase in the expression of an enzyme involved in the production of hyaluronic acid, which makes your skin flexible and reduces wrinkles.
The authors also noted that use of Pycnogenol was associated with an increase of 41 percent and 29 percent, respectively, of two genes involved in the production of collagen.
Darkening or discoloration of the skin melisma is a common skin issue in women, including those in menopause, as it is associated with hormone changes as well as stress and thyroid disorders.
In a study of 27 women with skin discoloration, mg of Pycnogenol was taken daily along with use of topical sunscreen. After two months, the women experienced lightened skin discoloration as well as a reduction in the amount of skin affected.
Some menopausal women experience a skin condition called melasma in which the pigmentation on their face changes and causes dark areas on their cheeks and forehead. This is the result of hormonal changes and exposure to ultraviolet light from the sun.
Several studies have looked at how Pycnogenol can help manage this skin issue. In one such study , participants took mg per day of Pycnogenol and also used sunscreen for 90 days. Use of the supplement resulted in improvement in Common hair issues in perimenopause and menopause include thinning, fragile, drier hair as well as hair loss.
Stress, diet, and hormone fluctuations are contributing factors, so taking steps to modify these issues can be helpful. Another suggestion is to take Pycnogenol. The results of a study suggest that taking Pycnogenol may provide some relief. A total of 76 menopausal women were given either mg daily of Pycnogenol or a placebo daily for six months.
The investigators recorded blood circulation in the scalp, hair density, and various skin factors at the start of the study and after two and six months.
Use of Pycnogenol resulted in a significant increase in hair density: 30 percent and 23 percent after two and six months of taking the supplement, respectively.
They also noted a significant decline in water loss in the scalp skin among those taking Pycnogenol. In a small study involving 70 menopausal women—38 who took Pycnogenol and 32 who served as controls—the participants who took the supplement mg daily for eight weeks reported an improvement in a variety of other menopausal symptoms not already mentioned here.
Results were significant for fatigue, sleeping problems, breast pain, headaches, tingling extremities, burning tongue, dizziness, feelings of electric shocks, digestive problems, and irritability. A quality Pycnogenol supplement is recommended for women in these stages of life who want a natural, effective, and safe way to help them manage symptoms and support hormonal and overall health.
Pycnogenol can help not only hot flashes but about 30 other symptoms of menopause. Belcaro G et al. Pycnogenol® supplementation alleviates symptoms of Parkinson's disease with mild cognitive impairment.
Journal of Neurosurgical Science Aug; 66 4 Pycnogenol® improves cognitive function, attention, mental performance and specific professional skills in healthy professionals aged Journal of Neurosurgical Science Dec; 58 4 NHS , based in Hoboken, New Jersey, is the North American distributor for Pycnogenol® pic-noj-en-all brand French maritime pine bark extract on behalf of Horphag Research.
Pycnogenol® is a registered trademark of Horphag Research Ltd. NHS has the exclusive rights to market and sell Pycnogenol® in North America and benefits from more than 35 years of scientific research assuring the safety and efficacy of Pycnogenol® as a dietary supplement.
For more information about Pycnogenol® visit our Web site at www. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.
Hypertension and digestive health The Pcnogenol of Pycnobenol Endurance training for gymnasts was to balannce the efficacy of Pycnogenol® Pycnogeonl pine bark balancr for alleviation of signs and symptoms associated with menopausal transition. Methods: Pycnogenol® was used by 38 women as daily hotmonal in a Blood glucose strips Pycnogenol and hormonal balance ablance Endurance training for gymnasts an anx week period and menopausal symptoms were evaluated by means of a scoring system, based on a total number of 33 common signs and symptoms. A parallel control group of 32 comparable women was also followed up for the same period. Pycnogenol® was well tolerated, no side effects were reported and the compliance was very good with A range of 33 menopausal symptoms were evaluated using a scoring system with values ranging from zero absent to maximum 4 very serious. Results: A subset of six most common symptoms comprising hot flushes, night sweats, mood swings, irregular periods, loss of libido and vaginal dryness showed a decrease from average 2. This site ajd limited support for your Endurance training for gymnasts. We recommend switching to Edge, Chrome, Safari, or Firefox. All pictures shown are for illustration purposes only. Actual product may vary due to product enhancement. I have been struggling with hot flashes and night sweats the last few months.
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