Prevenrion is a prevdntion of cancer treatment that Immunit-yboosting your immune system Immunity-boosting for cancer prevention cancer. The immune system helps your body preventuon infections and other camcer. It is made Immunuty-boosting of white blood Immunity-noosting and organs Immuniity-boosting tissues of the Immunjty-boosting system.
Prevenion is dor type Immunity-boowting biological therapy. Biological therapy is a type of treatment that Imunity-boosting substances made from Immunity-boosting for cancer prevention organisms to treat ccancer.
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These Immknity-boosting called tumor-infiltrating lymphocytes or TILs, are a Immunity-boosting that the immune system is responding to the tumor. Even though Immuunity-boosting immune system can prevent or slow cancer Immunity-noosting, cancer cells have ways cwncer avoid destruction by the immune Immunigy-boosting.
For example, cancer cells may:. Learn more Immunity-boostibg immune checkpoint Immuhity-boosting. T-cell Immunity-boosting for cancer prevention cancre may also be called preventoin cell therapy, adoptive immunotherapy, cander immune cell therapy.
Learn more about T-cell transfer therapy. Learn Immuniity-boosting about monoclonal antibodies, Immunity-boosting for cancer prevention. Learn more about Immuniry-boosting treatment vaccines.
Learn more about immune system preevention. Immunotherapy drugs have been approved to treat Immunity-boosting for cancer prevention types Selenium framework architecture cancer. However, Immunity-booeting is Ongoing research in sports nutrition yet peevention widely used as Lreventionchemotherapyor radiation therapy.
To Immunity-bposting about Immunity-boostlng immunotherapy Im,unity-boosting be used to treat your cancer, see the RMR and long-term weight management ® adult Immunity-boosting for cancer prevention treatment summaries and childhood cancer treatment summaries.
Immunotherapy can cause side effectsmany of which happen when the immune system that has been revved-up to act against the cancer also acts against healthy cells and tissues in your body. Learn more about immunotherapy side effects.
Outpatient means you do not spend the night in the hospital. You may have treatment every day, week, or month. Some types of immunotherapy given in cycles. A cycle is a period of treatment followed by a period of rest. The rest period gives your body a chance to recover, respond to immunotherapy, and build new healthy cells.
You will see your doctor often. He or she will give you physical exams and ask you how you feel. You will have medical tests, such as blood tests and different types of scans.
These tests will measure the size of your tumor and look for changes in your blood work. Home About Cancer Cancer Treatment Types of Cancer Treatment Immunotherapy to Treat Cancer. Immunotherapy to Treat Cancer Immunotherapy is a type of cancer treatment that helps your immune system fight cancer.
On This Page How does immunotherapy work against cancer? What are the types of immunotherapy? Which cancers are treated with immunotherapy? What are the side effects of immunotherapy? How is immunotherapy given? Where do you go for immunotherapy?
How often do you receive immunotherapy? How can you tell if immunotherapy is working? What is the current research in immunotherapy? How do you find clinical trials that are testing immunotherapy? How does immunotherapy work against cancer?
Different forms of immunotherapy may be given in different ways. These include: intravenous IV The immunotherapy goes directly into a vein.
oral The immunotherapy comes in pills or capsules that you swallow. topical The immunotherapy comes in a cream that you rub onto your skin. This type of immunotherapy can be used for very early skin cancer.
intravesical The immunotherapy goes directly into the bladder. How often and how long you receive immunotherapy depends on: your type of cancer and how advanced it is the type of immunotherapy you get how your body reacts to treatment You may have treatment every day, week, or month.
Researchers are focusing on several major areas to improve immunotherapy, including: Finding solutions for resistance. Researchers are testing combinations of immune checkpoint inhibitors and other types of immunotherapy, targeted therapy, and radiation therapy to overcome resistance to immunotherapy.
Finding ways to predict responses to immunotherapy. Only a small portion of people who receive immunotherapy will respond to the treatment. Finding ways to predict which people will respond to treatment is a major area of research. Learning more about how cancer cells evade or suppress immune responses against them.
A better understanding of how cancer cells get around the immune system could lead to the development of new drugs that block those processes. How to reduce the side effects of treatment with immunotherapy.
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: Immunity-boosting for cancer prevention| The immune system and cancer | ASCO Annual Meeting Immunotherapy for lung cancer, gastrointestinal cancers and targeted therapy for breast cancer. Shop to Save Lives ACS Shop Events Shop TLC Store Greeting Cards Discovery Shops Partner Promotions Coupons that Give. Some types of immunotherapy given in cycles. For additional clinic guidelines for COVID, please visit our Coronavirus Advisory page. Researchers are testing vaccines for many types of cancer, including: Bladder cancer. |
| Immunotherapy to Treat Cancer | Others focus Immunity-boostign cancer that Natural green tea come back, or recurred. Resource Search. Cancer Care Finding Care Immuniry-boosting Treatment Decisions Treatment Side Effects Palliative Care Advanced Cancer. Learn about CRI's impact. A vaccine exposes your immune system to a foreign protein, called an antigen. ACS Research on Top Cancers ACS Research News. |
| Study: Potential Cancer Therapy May Boost Immune Response | As of December , the FDA has approved immunotherapies as treatments for nearly 20 cancers as well as cancers with a specific genetic mutation Learn more about immunotherapies for different types of cancer. Cancer immunotherapy treats the patient—by empowering their immune system—rather than the disease itself like chemotherapy and radiation. Patients may be tested for biomarkers that may indicate whether cancer immunotherapy would be an effective treatment. Side effects of immunotherapy may results from stimulation of the immune system and may range from minor inflammation and flu-like symptoms, to major, potentially life-threatening conditions similar to autoimmune disorders. Common side effects may include but are not limited to skin reactions, mouth sores, fatigue, nausea, body aches, headaches, and changes in blood pressure. Conventional cancer treatments also have a range of side effects with a wide range of severity. Chemotherapy is intended to target fast-growing cancer cells, so it may damage other fast-growing normal cells in your body. Common side effects may include but are not limited to hair loss, nausea, diarrhea, skin rash, and fatigue. Radiation uses radioactive particles to destroy cancer cells in a localized area, so it may damage other healthy cells in that area. Side effects may be associated with the area of treatment, such as difficulty breathing when aimed at the chest, or nausea when aimed at the stomach. Skin problems and fatigue are common. The goal of surgery is to remove the cancerous tumor or tissue and varies according to the type of surgery performed. Common side effects may include but are not limited to pain, fatigue, swelling, numbness, and risk of infection. Learn more about immunotherapy side effects. Cancer immunotherapy offers the possibility for long-term control of cancer. Visit the timeline of immunotherapy. Learn more about how the immune system functions. Immunotherapy treatments can be broken down into five types: Targeted antibodies are proteins produced by the immune system that can be customized to target specific markers known as antigens on cancer cells, in order to disrupt cancerous activity, especially unrestrained growth. Some targeted antibody-based immunotherapies, known as antibody-drug conjugates ADCs , are equipped with anti-cancer drugs that they can deliver to tumors. Others, called bi-specific T cell-engaging antibodies BiTEs , bind both cancer cells and T cells in order to help the immune system respond more quickly and effectively. All targeted antibody therapies are currently based on monoclonal antibodies clones of a parent bonding to the same marker s. In CAR T cell therapy, cancer-fighting T cells are modified and equipped with specialized cancer-targeting receptors known as CARs chimeric antigen receptors that enable superior anti-cancer activity. Natural killer cells NKs and tumor-infiltrating lymphocytes TILs can also be enhanced and reinfused in patients. Oncolytic virus therapy uses viruses that are often, but not always, modified in order to infect tumor cells and cause them to self-destruct. This can attract the attention of immune cells to eliminate the main tumor and potentially other tumors throughout the body. Cancer vaccines are designed to elicit an immune response against tumor-specific or tumor-associated antigens, encouraging the immune system to attack cancer cells bearing these antigens. Cancer vaccines can be made from a variety of components, including cells, proteins, DNA, viruses, bacteria, and small molecules. Some versions are engineered to produce immune-stimulating molecules. Preventive cancer vaccines inoculate individuals against cancer-causing viruses and bacteria, such as HPV or hepatitis B. Immunomodulators govern the activity of other elements of the immune system to unleash new or enhance existing immune responses against cancer. Some, known as antagonists, work by blocking pathways that suppress immune cells. Others, known as agonists, work by stimulating pathways that activate immune cells. Checkpoint inhibitors target the molecules on either immune or cancer cells, telling them when to start or stop attacking a cancer cell. Cytokines are messenger molecules that regulate maturation, growth, and responsiveness. Interferons IFN are a type of cytokine that disrupts the division of cancer cells and slows tumor growth. Interleukins IL are cytokines that help immune cells grow and divide more quickly. Adjuvants are immune system agents that can stimulate pathways to provide longer protection or produce more antibodies they are often used in vaccines, but may also be used alone. Learn more about how different facets of the immune system fight cancer. Learn more about immunotherapy vs chemotherapy. Find an immunotherapy clinical trial. Learn more about how the immune system can fight cancer. Learn about the different types of cancer immunotherapy. Visit the cancer immunology timeline of progress. Read our timeline of milestones in the field. Learn what immunotherapy is. Discover which immunotherapies are available for different cancers. Find out how different types of immunotherapy work. Get to know the scientists and patients behind the progress. Search for patient-specific resources. Learn about CRI's impact. Antibodies bind to antigens on threats in the body e. B Cells release antibodies to defend against threats in the body. Cytokines help immune cells communicate with each other to coordinate the right immune response. Dendritic Cells digest foreign and cancerous cells and present their proteins to immune cells that can destroy them. Macrophages engulf and destroy bacteria, virus-infected cells, and cancer as well as present antigens to other immune cells. Regulatory T Cells provide the checks and balances to ensure that the immune system does not overreact. How is immunotherapy given? Where do you go for immunotherapy? How often do you receive immunotherapy? How can you tell if immunotherapy is working? What is the current research in immunotherapy? How do you find clinical trials that are testing immunotherapy? How does immunotherapy work against cancer? Different forms of immunotherapy may be given in different ways. These include: intravenous IV The immunotherapy goes directly into a vein. oral The immunotherapy comes in pills or capsules that you swallow. topical The immunotherapy comes in a cream that you rub onto your skin. This type of immunotherapy can be used for very early skin cancer. intravesical The immunotherapy goes directly into the bladder. How often and how long you receive immunotherapy depends on: your type of cancer and how advanced it is the type of immunotherapy you get how your body reacts to treatment You may have treatment every day, week, or month. Researchers are focusing on several major areas to improve immunotherapy, including: Finding solutions for resistance. Researchers are testing combinations of immune checkpoint inhibitors and other types of immunotherapy, targeted therapy, and radiation therapy to overcome resistance to immunotherapy. Finding ways to predict responses to immunotherapy. Only a small portion of people who receive immunotherapy will respond to the treatment. Finding ways to predict which people will respond to treatment is a major area of research. This type of vaccine will only work if a person gets the vaccine before they are infected with the virus. There are 2 types of vaccines that prevent cancer approved by the U. Food and Drug Administration FDA :. HPV vaccine. The vaccine protects against the human papillomavirus HPV. If this virus stays in the body for a long time, it can cause some types of cancer. The FDA has approved HPV vaccines to prevent:. Cervical , vaginal , and vulvar cancers. Hepatitis B vaccine. This vaccine protects against the hepatitis B virus HBV. This virus can cause liver cancer. There are vaccines that treat existing cancer, called treatment vaccines or therapeutic vaccines. These vaccines are a type of cancer treatment called immunotherapy. They work to boost the body's immune system to fight cancer. Doctors give treatment vaccines to people who already have cancer. Different treatment vaccines work in different ways. They can:. Antigens, found on the surface of cells, are substances the body thinks are harmful. The immune system attacks the antigens and, in most cases, gets rid of them. This leaves the immune system with a "memory" that helps it fight those antigens in the future. Cancer treatment vaccines boost the immune system's ability to find and destroy antigens. Often, cancer cells have certain molecules called cancer-specific antigens on their surface that healthy cells do not have. When a vaccine gives these molecules to a person, the molecules act as antigens. They tell the immune system to find and destroy cancer cells that have these molecules on their surface. Some cancer vaccines are personalized. This means they are made for just 1 person. This type of vaccine is produced from samples of the person's tumor that are removed during surgery. Other cancer vaccines are not personalized and target certain cancer antigens that are not specific to an individual person. Doctors give these vaccines to people whose tumors have those antigens on the surface of the tumor cells. Most cancer vaccines are only offered through clinical trials , which are research studies that use volunteers. In , the FDA approved sipuleucel-T Provenge for people with metastatic prostate cancer , which is prostate cancer that has spread. Sipuleucel-T is tailored to each person through a series of steps:. White blood cells are removed from the person's blood. White blood cells help the body fight infection and disease. Next, the doctor puts the altered cells back into the person through a vein. This is similar to a blood transfusion. These modified cells teach the immune system to find and destroy prostate cancer cells. Another vaccine uses a weakened bacteria called Bacillus Calmette-Guérin BCG that is injected into the body. This weakened bacteria activates the immune system to treat early-stage bladder cancer. Cancer cells suppress the immune system. This is how cancer is able to begin and grow in the first place. Researchers are using adjuvants in vaccines to try to fix this problem. An adjuvant is a substance added to a vaccine to improve the body's immune response. Cancer cells start from a person's own healthy cells. As a result, the cancer cells may not "look" harmful to the immune system. The immune system may ignore the cells instead of finding and fighting them. Larger or more advanced tumors are hard to get rid of using only a vaccine. |
| You are here | Bacillus Immunity-boosting for cancer prevention BCG. Immunity-boostin are Immunityb-oosting side effects of Immunity-boosting for cancer prevention Exercise has been shown Cacao butter benefits stimulate the production of immune cells, improving their ability to detect and fight off infections and diseases. Research Events Jiler Conference Research Podcasts. If immunotherapy is a cancer treatment option for you, consider asking your health care team these questions:. |
| What the immune system does | Adjuvants are Immunity-boostkng system canfer that can stimulate pathways to provide longer protection Immunity-boosting for cancer prevention produce more antibodies they are often used in vaccines, but may also Green weight loss Immunity-boosting for cancer prevention alone. Food and Drug Administration had approved over 60 immunotherapies that together preventio almost every major cancer type:. Immunotherapies have been approved in the United States and elsewhere to treat a variety of cancers and are prescribed to patients by oncologists. American Cancer Society: Cancer Immunotherapy. Now studies are looking to see if the vaccine can help people with prostate cancer at earlier stages. |
Immunity-boosting for cancer prevention -
Cancer immunotherapy comes in a variety of forms , including targeted antibodies, cancer vaccines, adoptive cell transfer, tumor-infecting viruses, checkpoint inhibitors, cytokines, and adjuvants. Immunotherapies are a form of biotherapy also called biologic therapy or biological response modifier BRM therapy because they use materials from living organisms to fight disease.
Many immunotherapy treatments for preventing, managing, or treating different cancers can also be used in combination with surgery, chemotherapy, radiation, or targeted therapies to improve their effectiveness.
The immune system is precise, so it is possible for it to target cancer cells exclusively while sparing healthy cells. The immune system can adapt continuously and dynamically, just like cancer does, so if a tumor manages to escape detection, the immune system can re-evaluate and launch a new attack.
Immunotherapies have been approved in the United States and elsewhere to treat a variety of cancers and are prescribed to patients by oncologists. These approvals are the result of years of research and testing designed to demonstrate the effectiveness of these treatments. Immunotherapies are also available through clinical trials , which are carefully controlled and monitored studies involving patient volunteers.
This research is leading to new strategies to expand the number of patients who may potentially benefit from treatment with immunotherapy. Immunotherapy holds the potential to become more precise, more personalized, and more effective than current cancer treatments—and potentially with fewer side effects.
Learn more about how you can support new breakthroughs in cancer immunotherapy research. Many cancer patients and caregivers may be familiar with traditional treatments, such as chemotherapy and radiation. Immunotherapy has been approved in the U. and elsewhere as a first-line of treatment for several cancers, and may also be an effective treatment for patients with certain cancers that are resistant to prior treatment.
Immunotherapy may be given alone or in combination with other cancer treatments. As of December , the FDA has approved immunotherapies as treatments for nearly 20 cancers as well as cancers with a specific genetic mutation.
Immunotherapy may be accompanied by side effects that differ from those associated with conventional cancer treatments, and side effects may vary depending on the specific immunotherapy used. In most cases, potential immunotherapy-related side effects can be managed safely as long as the potential side effects are recognized and addressed early.
Clinical studies on long-term overall survival have shown that the beneficial responses to cancer immunotherapy treatment can be durable—that is, they continue even after treatment is completed.
Cancer immunotherapy originated in the late s with a cancer surgeon named Dr. William B. Coley — He discovered that infecting cancer patients with certain bacteria sometimes resulted in tumor regression and even some complete remissions.
In , the FDA approved the first cancer immunotherapy, a bacteria-based tuberculosis vaccine called Bacillus Calmette-Guérin BCG , which was shown to be effective for patients with bladder cancer.
While many of our cells grow and divide naturally, this behavior is tightly controlled by a variety of factors, including the genes within cells. When no more growth is needed, cells are told to stop growing. Unfortunately, cancer cells acquire defects that cause them to ignore these stop signals, and they grow out of control.
Because cancer cells grow and behave in abnormal ways, this can make them stand out to the immune system, which can recognize and eliminate cancer cells through a process called immunosurveillance. Sometimes cancer cells develop ways to evade and escape the immune system, which allows them to continue to grow and metastasize, or spread to other organs.
Chemotherapy is a direct form of attack on rapidly-dividing cancer cells, but this can affect other rapidly dividing cells including normal cells.
These direct effects of chemotherapy, however, last only as long as treatment continues. Immunotherapy may take more time to have an effect, but those effects can persist long after treatment ceases. As of March , the U. Food and Drug Administration had approved over 60 immunotherapies that together cover almost every major cancer type:.
New immunotherapies are being developed and immunotherapy clinical trials are under way in nearly all forms of cancer. People with mild autoimmune diseases are able to receive most immunotherapies.
However, each patient should speak with his or her doctor regarding the options that are most appropriate. People with HIV who are receiving effective anti-viral treatment and whose immune systems are functioning normally may respond to cancer immunotherapy and are therefore eligible to receive immunotherapy, both as a standard of care and as part of a clinical trial.
The administration and frequency of immunotherapy regimens vary according to the cancer, drug, and treatment plan. Clinical trials can offer many valuable treatment opportunities for patients.
Discuss your clinical trial options with your doctor. Immunotherapy treatments may take longer to produce detectable signs of tumor shrinkage compared to traditional therapies. Sometimes tumors may appear to grow on scans before getting smaller, but this apparent swelling may be caused by immune cells infiltrating and attacking the cancer.
Many patients who experience this phenomenon, known as pseudoprogression, often report feeling better overall. For more than 65 years , the Cancer Research Institute CRI has been the pioneer in advancing immune-based treatment strategies against cancer. CRI provides financial support to scientists at all stages of their careers along the entire spectrum of immunotherapy research and development: from basic discoveries in the lab that shed light on the fundamental components and mechanisms of the immune system and its relationship to cancer, to efforts focused on translating those discoveries into lifesaving treatments that are then tested in clinical trials for cancer patients.
Cancer immunologists focus on developing immunotherapies to boost those natural defenses. Cancer immunotherapies also are known as biologic therapy, biotherapy, or biological response modifier therapy, and include checkpoint blockade, cancer vaccines, monoclonal antibodies, oncolytic virus therapy, T cell transfer, and other immune-modulating drugs such as cytokines and other adjuvant therapies.
These effective ways for preventing, managing, or treating different cancers can be used in conjunction with surgery, chemotherapy, or radiation.
The earliest forms of what would later be considered the start of cancer immunotherapy originated with research done by Dr. Coley , a cancer surgeon and father of CRI founder Helen Coley Nauts. Cancer immunology is a relatively young field, but advances in treatment are aided by donor support.
bind to antigens on threats in the body e. destroy thousands of virus-infected cells each day, and are also able to seek out and destroy cancer cells.
digest foreign and cancerous cells and present their proteins to immune cells that can destroy them. engulf and destroy bacteria, virus-infected cells, and cancer as well as present antigens to other immune cells.
Organs, tissues, and glands around your body coordinate the creation, education, and storage of key elements in your immune systems. Thin tube about 4 to 6 inches long in the lower right abdomen.
Soft, sponge-like material found inside bones. Contains immature cells that divide to form more blood-forming stem cells, or mature into red blood cells, white blood cells B cells and T cells , and platelets.
Cells lining this set of organs and glands, as well as the bacteria throughout it, influence the balance of the immune system. Small glands located throughout the body that filter bacteria, viruses, and cancer cells, which are then destroyed by special white blood cells. Nasal mucus catches these pathogens so the immune system can learn to defend against them.
This organ is not only a physical barrier against infection but also contains dendritic cells for teaching the rest of the body about new threats. The skin microbiome is also an important influence the balance of the immune system.
An organ located to the left of the stomach. Filters blood and provides storage for platelets and white blood cells. Also serves as a site where key immune cells B cells multiply in order to fight harmful invaders. A set of organs that can stop germs from entering the body through the mouth or the nose.
They also contain a lot of white blood cells. Small gland situated in the upper chest beneath the breastbone. Functions as the site where key immune cells T cells mature into cells that can fight infection and cancer.
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For additional information, review our Privacy Policy. Skip to content. Immunotherapy can:. Educate the immune system to recognize and attack specific cancer cells. Provide the body with additional components to enhance the immune response.
Boost immune cells to help them eliminate cancer. Unleashing the power of the immune system is a smart way to fight cancer. Cancer immunotherapy can work on many different types of cancer. A new approach to cancer therapy shows potential to transform the commonly used chemotherapy drug gemcitabine into a drug that kills cancer cells in a specialized way, activating immune cells to fight the cancer, according to a study led by Cedars-Sinai Cancer investigators.
The findings, made in human and mouse cancer cells and laboratory mice, were published today in the peer-reviewed journal Nature Communications.
The combination of drugs delivered a " one-two punch " of killing tumor cells and activating immune cells, said Keith Syson Chan, PhD , a Cedars-Sinai Cancer translational scientist and corresponding author of the study.
Kazukuni Hayashi, PhD, is the first author. Since the s, the main treatment for killing cancer cells has involved chemotherapy drugs, which kill the cells directly. The " go " signal prompts immune cells—called dendritic cells—to spur T cells to eradicate tumors. Instead, most current chemotherapies for pancreatic, bladder, breast, ovarian and non-small cell lung cancers not only are non-immunogenic—they suppress the immune system.
Certain chemotherapy drugs such as gemcitabine do kill cancer cells and release the " go " signal for an immune response. Scientists, therefore, have believed that those drugs are immunogenic.
That is not entirely the case, though, Chan said. The solution to that balance, the investigators discovered, is the anti-inflammatory drug celecoxib, which removed the brake so that only the " go " signal remained. The dendritic and T cells then were better able to perform their immune responses.
Gemcitabine was transformed into an immunogenic drug. Chan and Hayashi said they believe that the immune response will perform even better with an immunotherapy drug added to a gemcitabine and celecoxib treatment regimen.
They look forward, they said, to testing the efficacy of the new treatment in randomized, placebo-controlled human trials in collaboration with their Cedars-Sinai clinical colleagues. This study unveils at least one potential mechanism explaining these failures, and more importantly, provides a potential solution.
Research reported in this publication was supported in part by the Department of Defense under award numbers CA and F31 CA The investigators report no conflicts of interest.
The immune system Immunity-boosting for cancer prevention the system Immmunity-boosting your body prveention fights off infection. Immunotherapy is a form of medical treatment that activates your immune system to help fight cancer. There are many different types of immune cells in your body. Different cells fight different types of cancer. This protects healthy cells. Gain in-depth knowledge about Immunity-boostign and the unique role your fancer system preention in preventing, controlling, and Immunity-boosting for cancer prevention a variety of cancers. Immunity-boosting for cancer prevention immunotherapy Immuniity-boosting in a variety of formsincluding targeted antibodies, cancer vaccines, adoptive cell transfer, Mental performance coaching viruses, checkpoint inhibitors, cytokines, and adjuvants. Immunotherapies are a form of biotherapy also called biologic therapy or biological response modifier BRM therapy because they use materials from living organisms to fight disease. Many immunotherapy treatments for preventing, managing, or treating different cancers can also be used in combination with surgery, chemotherapy, radiation, or targeted therapies to improve their effectiveness. The immune system is precise, so it is possible for it to target cancer cells exclusively while sparing healthy cells.Video
Frontier Science #20 - Cancer Vaccines \u0026 Translational Medicine w/ Nora Disis - Prof. @ UW - BIOS
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