One of their Cognitive resilience building product lines Turrmeric Turmeric Supreme, which is produced using an Turmeric supplement reviews curcuminoid testing method. Also see our revieews to the Tuurmeric Do any supplements help with fatty liver disease? Statistically, there was no difference in efficacy between the low and higher doses, although those who took the higher dose reported more adverse effects, such as abdominal discomfort and diarrhea, than those who took the lower dose or placebo.

Turmeric supplement reviews -

Clinical studies indicate that Meriva curcumin may be helpful in the treatment and management of osteoarthritis. This supplement comes in capsule form which some reviewers find on the larger size for swallowing.

Super Bio-Curcumin from Life Extension is an approved pick by ConsumerLab. com and passes its test for purity, potency and labeling accuracy. This pick contains BCM Bio-Curcumin extract for better absorbability. According to the company, BCM stays in your bloodstream longer and is up to seven times more absorbable than standard curcumin.

Each capsule contains milligrams of BCM turmeric complex and includes essential oils from turmeric root. This product is Non-GMO and available in multiple strengths. Life Extension also sells multiple turmeric offerings including turmeric paired with black cumin oil for better immune health and turmeric paired with ginger to compliment turmeric's health benefits.

While there are a good deal of turmeric supplements to choose from, we evaluated dozens at the Good Housekeeping Institute's Nutrition Lab and our choices were based on the following criteria:.

We reviewed marketing claims, ingredient lists and product quality, and prioritized companies that test for heavy metals, pesticide and herbicide contamination, among other items of concern. We also highlighted companies that have strict internal quality control standards.

We kept in mind dosage and supplement form, be it a capsule, tablet or gummy. We also looked for turmeric specifically targeted for different purposes, such as inflammation response and joint and immune support.

There are many types of turmeric supplements available to choose from and in different strengths. If you have decided to take a turmeric supplement, here are a few things to keep in mind:. If you don't like swallowing capsules, there are plenty of other options to choose from. Pay attention to serving size as some supplements require multiple dosages throughout the day.

For example, they may be better absorbed when paired with black pepper or black pepper extract, which is sometimes listed as piperine or bioperine. They are also better absorbed with a fat source so you may want to take your supplement with a meal.

Lecithin is found in foods like eggs, vegetable oils, butter, yogurt and other lactose products. There are also many products that contain turmeric with enhanced bioavailability such as Mervia, Longvida and NovaSOL.

As with most things, higher prices are not necessarily a good indicator of quality. Turmeric and curcumin's reputation as a superfood is well deserved because it is associated with many health benefits, but as with any supplement more research is needed before a definitive conclusion can be reached.

Some of the purported benefits include:. Turmeric alone will likely not help decrease the symptoms associated with IBD or ulcerative colitis UC , explains Greene. However, she adds that a randomized clinical control trial showed that taking supplemental curcumin with a common medication used to treat UC was more successful in helping patients with mild to moderate UC achieve remission than the medication on its own.

According to Calderon, who suffers from IBD herself, and specializes in treating patients with IBD, "studies show that turmeric may be beneficial for cases of mild IBD when used together with medication because of the anti-inflammatory and antioxidant properties.

Turmeric may help decrease the pain and discomfort associated with both types of arthritis due to its anti-inflammatory properties.

A randomized clinical control trial showed that taking milligrams of curcumin four times per day was as effective at relieving reoccurring symptoms such as gas, bloating and nausea as the medication Omeprazole. Recent research suggests that curcumin may have effectiveness as an anti-diabetic agent including improving insulin resistance and reducing blood glucose.

A recent study indicated that supplementing with milligrams of curcumin daily reduced fasting blood glucose and weight in patients with type 2 diabetes. However, if you are diabetic and taking medication to control it, it may increase the risk of low blood sugar and therefore should be discussed with your doctor.

There is frequently confusion regarding turmeric versus curcumin. Turmeric is a plant in the ginger family, Z ingiberaceae , and its underground stem, also known as its rhizome, is the part used as a culinary spice. This is the source for the spice that is used in cooking and for juicing.

Curcumin , on the other hand, is derived from the turmeric plant and is the active ingredient in turmeric where many of the health benefits come from. Curcumin has been widely studied for its anti-inflammatory benefits as well as many other health issues, including improving glucose control.

Curcumin can be unstable, which could result in lower bioavailability, meaning less of a medicinal compound reaches the bloodstream. There are now several patented turmeric compounds that we have included in our story and that claim increased bioavailability.

Turmeric used as a spice in food is generally considered safe , although whenever you are ingesting it in a supplemental form you should first consult with your healthcare provider.

However, it may cause mild gastrointestinal distress such as reflux, nausea or upset stomach in some individuals. As discussed earlier in the article, turmeric may lower blood sugar levels, which means if you have diabetes it may cause low blood sugar and should be discussed with your doctor.

Additionally, it contains natural blood thinning properties and therefore may interact with other medications you may be taking. As always, it is important to work with your healthcare provider prior to adding supplements to your diet.

As a registered dietitian, Amy Fischer has worked with thousands of patients in several clinical settings for over 10 years, including working with gastrointestinal and heart transplant patients.

Her goal is to help people improve their health through whole foods and a nutritious diet. Amy believes that food is to be enjoyed whatever your diet goals may be and that ideally, the focus should be on improving overall health, eating and living better.

She has written about many other supplements for Good Housekeeping, including magnesium , menopause supplements and fish oil benefits. She holds a bachelor's degree in journalism from Miami University of Ohio and a master's degree in clinical nutrition from NYU.

Prior to Good Housekeeping , she worked at one of the largest teaching hospitals in New York City as a cardiac transplant dietitian.

She has authored numerous chapters in clinical nutrition textbooks and has also worked in PR and marketing for food company start-ups.

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Pros NSF Certified for Sport Sustained release formula. Cons Multiple doses recommended. Pros USP certified Budget friendly. Cons Does not contain black pepper. Pros ConsumerLab. com approved USDA certified organic. Cons Contains probiotics, which some people may not want.

Advertisement - Continue Reading Below. Pros Third-party tested Herbs can be traced from farm to shelf. Cons Multiple dosages may be needed. Pros Third-party approved Contains a high amount of turmeric relative to the others. of water immediately before sleep for two months only slightly reduced the average overall symptom scores compared to placebo an average reduction of 0.

Ulcerative colitis, Crohn's disease, and other GI conditions: Curcumin may be helpful for people with ulcerative colitis when taken in addition to standard medication e.

In one study, 50 people with mild to moderate ulcerative colitis not responsive to mesalamine were given 1. At week four, none of the patients who received placebo achieved remission, while a startling A study among 56 men and women in Iran with mild to moderate ulcerative colitis found that 80 mg of an enhanced-bioavailability "nanoparticle" formulation of curcumin similar to Theracurmin taken three times daily mg per day in addition to mesalamine for one month modestly decreased urgency of bowel movements and improved self-reported well-being, but did not decrease blood in the stool or colitis-related skin ulcers compared to mesalamine alone Masoodi, J Cell Biochem One gram of curcumin taken twice daily in addition to mesalamine or sulfasalazine for six months helped maintain remission from ulcerative colitis compared to standard medications plus placebo Hanai, Clin Gastroenterol Hepatol , but a lower dose mg of curcumin daily did not improve remission rates or improve mucosal healing compared to placebo in men and women with active ulcerative colitis taking mesalamine Kedia, World J Gastrointest Pharmacol Ther A very small pilot study suggests a benefit with curcumin in treating ulcerative proctitis and Crohn's disease Holt, Digestive Diseases and Sciences The results of human studies using turmeric for treating gastric or duodenal ulcers conflict.

At least two studies found no benefit while a third found that turmeric improved symptoms. Additionally, while some animal research suggests that turmeric might help prevent ulcers, other animal research suggests that turmeric might increase the risk of ulcers.

A preliminary study in five people with familial adenomatous polyposis a genetic disorder causing hundreds of intestinal polyps and eventually colorectal cancer suggested that curcumin might cause regression of polyps in such people, and such is the case with other non-steroidal anti-inflammatory drugs.

However, a month clinical study in which patients were given 1, mg of pure curcumin twice daily or a placebo found no significant difference in the mean number of polyps or polyp size between the two groups.

Possibly explaining the different outcomes of the studies, the researchers noted the earlier, positive, study used a lower total dose of curcumin mg given three times daily but it included black pepper extract to increase bioavailability as well as quercetin 20 mg per dose Cruz-Correa, Gastroenterology There is clinical evidence that curcumin about 1, mg per day can be effective in treating symptoms mainly pain and inflammation of osteoarthritis and rheumatoid arthritis, although larger studies are needed to confirm these findings before a definitive recommendation can be made Daily, J Med Food More details regarding the use of curcumin in each type of arthritis are below.

Rheumatoid arthritis: Curcumin may help treat symptoms of rheumatoid arthritis -- although it is not superior to non-steroidal anti-inflammatory drugs, and it does not appear to help maintain or prolong remission.

Two small studies have shown that curcumin may reduce symptoms of rheumatoid arthritis including joint swelling and stiffness and walking time.

In one study, 1, mg of curcumin reduced symptoms, but not as well as the non-steroidal anti-inflammatory drug NSAID , phenylbutazone Deodhar, Indian J Med Res, In another study, mg twice daily of a bioavailability-enhanced curcumin product BCM, Biocurcumin was comparable to a low dose 50 mg of diclofenac an NSAID twice daily, after 8 weeks.

Combining the curcumin and diclofenac was no more effective than either one alone Chandran, Phytother Res A weakness of this study is that there was no placebo control group.

Note: The curcumin used in this study, BCM is listed as an ingredient in Terry Naturally CuraMed tested in this Review. A small, day study in India found a highly bioavailable formulation of curcumin to greatly reduce pain and inflammation in people with rheumatoid arthritis.

Although improvements were noted in biochemical markers of inflammation relative to placebo, it was not mentioned whether the improvements in symptoms were statistically significant relative to placebo: Due to small sample sizes in the study, they may not have been. This, and the fact that most of the study authors were employed by the product manufacturer, raise doubts about the importance of the findings.

This ingredient does not appear to be in any of the products tested in this review. Curcumin supplementation did not help to maintain or prolong flare-free remission of rheumatoid arthritis in a study among men and women average age 52 in India who tapered off their regular medication.

Osteoarthritis: Several short-term 6 to 12 week studies focusing mainly on osteoarthritis of the knee have shown generally modest reductions in pain, but less improvement in function, with different turmeric formulations. To reduce the risk of gastrointestinal side effects, it may be best to start with a low dose which, at least in one study, was as effective as a higher dose.

Curcumin supplementation does not appear to reduce pain during rehabilitation from knee surgery , although it may have a slight protective effect on knee cartilage after surgery. A small placebo-controlled study of people with mild to moderate osteoarthritis of the knee found treatment with curcuminoids to be helpful.

Six weeks of daily treatment with 1, mg of a curcuminoid complex resulted in significantly greater reductions in the severity of osteoarthritis symptoms than with placebo, with a particular reduction in pain and an improvement in physical function. Reports of stiffness were reduced in both the treatment and placebo groups, although not significantly more so in the treatment group Panahi, Phytother Res The curcumin used in the study was taken three times each day as a capsule containing mg of curcuminoids as C3 complex® including 5 mg of Bioperine®, a bioavailability enhancer.

The BCM version of curcumin taken as mg capsules of CuraMed , each with mg curcuminoids was also found to modestly reduce pain-related symptoms of knee osteoarthritis as compared to placebo which also showed improvement in a week study in Armenia, although it was somewhat more effective in improving physical performance when taken combined with a Boswellia extract as Curamin — mg curcuminoids and mg boswellic acid, not tested in this Review, but found in Terry Naturally Curamin.

The capsules were taken three times a day Haroyan, BMC Compl Alt Med Pain decreased by 8 points on a scale from 1 to in those who took placebo, compared to decreases of Statistically, there was no difference in efficacy between the low and higher doses, although those who took the higher dose reported more adverse effects, such as abdominal discomfort and diarrhea, than those who took the lower dose or placebo.

The extract was divided into two doses with meals Henrotin, Arthritis Res Ther A study in Australia among 98 men and women average age 59 with mild to moderate knee osteoarthritis who were not already regularly taking anti-inflammatory medications or other supplements for their condition showed that taking mg of standardized curcumin extract providing mg of curcuminoids Curcugen , from DolCas Biotech, LLC — which funded the study twice daily for eight weeks modestly reduced self-reported knee pain compared to placebo.

However, supplementation did not significantly improve knee stiffness, function in daily living or sports and recreational activities, or quality of life impacted by knee pain compared to placebo Lopresti, Nutrients Supplementation also modestly improved self-reported knee stiffness, and certain measures of knee function compared to placebo, with greater benefit shown among those who took the higher daily dose of extract.

For example, the distance participants were able to walk during a six-mile walking treadmill test increased, respectively, by 32 and 60 yards among those who took the mg and mg daily dose of extract, while there was no improvement in walking distance among those who took the placebo Jagtap, J Orthop Res Ther There is only slight additional benefit from curcumin in people already taking an anti-inflammatory drug for osteoarthritis.

Not surprisingly, at two months both groups reported major improvements in joint pain, stiffness and function, but the curcumin group showed only slightly better improvement in pain and function, e. The curcumin group had greater decreases in markers of oxidative stress, but not in levels of IL-1 beta, a marker of inflammation.

Neither group showed knee joint improvements on X-ray. Srivastava, Inflammopharmacol Interestingly, taking curcumin alone or in combination with fish oil did not reduce joint pain in a placebo-controlled study of sedentary, obese men and women with mild, chronic osteoarthritis pain in the knees, lower back or shoulders Kuszewski, Rheumatol Adv Pract Although most arthritis studies have focused on curcumin, one study suggested that other constituents in turmeric may have a role.

This study used a turmeric extract NR-INF Turmacin ®, Natural Remedies, India, mg twice daily that contained turmeric polysaccharides but no curcumin. The extract was found to perform better than placebo and better than chondroitin sulfate among people with knee osteoarthritis Madhu, Inflammopharm Turmacin is included as a branded ingredient in combination products such as TurmaBoost by Wild Nature and TurmaFLEX by Stop Aging Now.

Turmacin has also been evaluated in people with knee pain after exercise see below. Another study that evaluated turmeric polysaccharides with curcuminoids found modest improvement in pain but no reduction in swelling.

The study was partially funded by the company that manufactured the extract Turmacin Plus , Natural Remedies.

Some, although not all, people in this study also used pain relievers, including anti-inflammatory drugs, or supplements for arthritis, and this may have impacted the results Wang, Ann Intern Med A study in Japan found that curcumin after knee surgery did not reduce self-reported pain compared to placebo.

While there was no reduction in pain, curcumin supplementation modestly reduced cartilage stiffness and roughness based on images and measurements taken during a follow-up arthroscopic procedure one year after surgery compared to placebo. The researchers speculated, based on animal studies, that this may be due to curcumin's ability to suppress inflammation in cartilage cells, but more research is needed to confirm this Nakagawa, Arthroscopy Several studies have evaluated formulations of curcumin on muscle function, recovery, and soreness after exercise.

Although some studies report a benefit, others have not and the usefulness of curcumin in muscle recovery and soreness remains questionable.

At best, if taken for a few days before intense exercise, curcumin may slightly reduce resulting inflammation and, if taken after exercise, it may reduce muscle damage and soreness.

Taking a turmeric supplement containing turmeric polysaccharides without curcumin does not appear to significantly reduce knee pain following exercise.

A small, placebo-controlled study in young healthy men found that 90 mg of a bioavailability-enhanced curcumin formula Theracurmin , from Theravalues Corp.

However, when the same dose of curcumin was taken for seven days after the exercise session, a significant reduction in muscle soreness as well as improved muscle strength and range of motion were observed starting about 3 to 6 days after the exercise session. Taken after exercise, curcumin also reduced blood levels of creatine kinase a marker of muscle damage , but did not reduce markers of inflammation Tanabe, Scand J Med Sci Sports Other studies that have suggested a benefit include two that used a bioavailability-enhanced curcumin, Meriva : One gave 20 healthy young men mg of curcumin from 1 gram of Meriva at breakfast and dinner for four days; they experienced significantly less soreness in their front thighs 48 hours after intense treadmill exercise on the third day of treatment than men given placebo Drobnic, JISSN Both groups reported similar decreases in self-reported pain and improvements in physical function.

However, it is not possible to draw conclusions from this study because there was no placebo-control and those taking curcumin were permitted to take anti-inflammatory drugs as needed Di Pierro, Eur Rev Med Pharmacol Sci Another small, placebo-controlled study in young healthy men found that 2, mg of curcumin taken twice daily a total daily dose of 5, mg providing roughly an equivalent amount of curcuminoids 2 days prior to, and 3 days after, intense leg exercise moderately reduced leg pain during subsequent exercise 24 and 48 hours later , indicating a reduction in delayed onset muscle soreness DOMS.

Effects on biochemical markers of inflammation, however, were inconclusive Nicol, Eur J Appl Physiol A small study among healthy young men and women given mg of curcuminoids from 1 gram of CurcuWIN daily for two months showed significantly reduced thigh muscle soreness 24 hours after muscle damaging exercise compared to placebo; however, there was no significant reduction in soreness one hour after exercise, nor 2 and 3 days after exercise, compared to placebo.

The curcuminoids reduced a marker of muscle damage creatine kinase two days after the exercise, but did not reduce other markers of inflammation, compared to placebo. A lower dose 50 mg of curcuminoids from mg CurcuWIN reduced muscle damage, but did not significantly decrease soreness Jager, FASB J In addition, while the placebo group lost muscle power 7 days after exercise, the curcumin group maintained it.

However, curcumin did not reduce blood markers of muscle damage or inflammation compared to placebo. The study was partially funded by the McCormick Science Institute Hillman, J Diet Suppl Studies that failed to show a benefit include one in which a daily dose of mg of a curcumin formula containing 80 mg curcumin plus fats to enhance absorption Longvida® Optimized Curcumin was given to healthy young men and women for two days before and four days after leg press exercises designed to induce muscle damage.

The curcumin did not reduce muscle soreness compared to placebo, but it did result in somewhat smaller increases in biological markers of inflammation McFarlin, BBA Clinical Another placebo-controlled study in France gave athletes 6, mg of curcumin plus 60 mg of the bioavailability enhancer piperine daily divided into 3 doses for two days before and after exercise-induced muscle damage.

The curcumin did not limit muscle damage or soreness and only limited loss of power in one of several exercises sprinting Delecroix, J Sports Sci Med A study in India among 15 healthy adults found that taking 2, mg of a turmeric extract that does not include curcumin Turmacin ® by Natural Remedies in the morning with food for 7 days slightly increased the time until discomfort during a stair climbing exercise by 32 seconds compared to baseline.

Although supplementation also slightly decreased self-reported knee pain intensity after exercise by 0. Furthermore, there was no placebo control, making it impossible to prove any benefit.

One person reported mild indigestion while taking Turmacin , although this side effect resolved on its own Raj, J Diet Suppl Curcumin has shown some short-term beneficial effects on cognition thinking and memory but longer-term studies have shown mixed results.

A small, but well-controlled study found that daily supplementation after breakfast with mg of a patented curcumin formula containing 80 mg curcumin plus fats to enhance absorption Longvida® Optimized Curcumin — Longvida funded the study significantly improved some aspects of cognitive function and fatigue in healthy men and women ages 60 to While these results are intriguing, it must be noted that no benefits were found on tests of word and picture recall Cox, J Psychopharm However , a longer study funded by the U.

NIH using a much higher dose of the same curcumin formula did not find benefit. It should be noted that, unlike the earlier study, Longvida was taken without food, which may have reduced its absorption — although Longvida is made with fats claimed to improve its absorption Santos-Parker, Nutr Healthy Aging Another study with Longvida providing 80 mg of curcumin taken with breakfast and, again, with dinner , showed that, after 16 weeks, it did not improve blood flow to the brain in older individuals ages 50 to 80 in Australia who were sedentary and obese.

The placebo-controlled trial also failed to show benefits with regard to blood pressure and cholesterol levels and there was no benefit from adding Longvida to fish oil supplementation 1, mg of DHA and mg EPA taken with breakfast and dinner.

The fish oil alone, however, showed some cardiovascular benefits, such as reductions in heart rate and triglycerides and an increase in HDL cholesterol, as well as reduced stiffness of the cerebral arteries but no significant effect on blood flow to the brain Kuszewski, Nutr, Met Cardio Dis Another small, but placebo-controlled study found that taking a capsule with 1, mg of turmeric powder with a nutritionally-bland breakfast resulted in improvements in short-term memory in people aged 60 years or older who were newly diagnosed with pre-diabetes.

When tested six hours after taking the turmeric, scores were 2. Scores did not improve among those who received placebo. Interestingly, turmeric had no effect on blood sugar or insulin levels.

The study also evaluated the effects of taking 2 grams of cinnamon, which had no effect on any of the parameters measured Lee, Asia Pac J Nutr A long-term study in Australia among older adults mainly in their 60s with normal cognitive function found that taking high-dose curcumin daily had no beneficial effect on cognitive function, nor on mood or general quality of life, compared to treatment with placebo over a month period.

According to the researchers, the rate of side effects would likely have been lower had the dose been gradually ramped-up rather than given at the full amount at the beginning of the study Rainey-Smith, Br J Nutr which funded the study twice daily for 18 months modestly improved measures of short-term memory, verbal memory and attention compared to placebo.

Those in the placebo group showed slight increases on PET scans in amyloid beta plaque and tau tangles in the hypothalamus and these increases were not found in the curcumin group, but no other significant differences between the groups were found in other parts of the brain. Although such changes are associated with Alzheimer's disease, the value of these findings is unclear Small, Am J Geriatr Psychiatry Several authors of the study have a financial interest in a tracer agent used in the PET scan and have been warned by the FDA for claiming it can be used to diagnose neurological conditions.

Laboratory and animal studies have shown curcumin inhibits several biological and chemical processes in brain cells associated with the development of Alzheimer's disease , including inflammation, oxidative stress and the formation and accumulation of amyloid-beta proteins which form brain plaques associated with Alzheimer's.

Animal studies also suggest curcumin may work similarly to acetylcholinesterase inhibitors, a class of drugs such as donepezil Aricept and galantamine Razadyne that may slow the progression of Alzheimer's symptoms. In mouse models of the disease, curcumin given orally appears to reach the brain and reduce oxidative damage and memory impairment Frautschy, Neurobiol Aging However, results have been less promising in clinical trials of curcumin in people with Alzheimer's.

For example, a preliminary study found that curcumin given to Alzheimer's disease patients did not significantly improve mental functioning compared to placebo Baum, J Clin Psychopharm Another study in people with mild to moderate Alzheimer's found that curcumin did not improve cognitive function or decrease amyloid-beta as measured in cerebrospinal fluid compared to placebo Ringman, Alzheimers Res Ther Curcumin mg of curcumin from turmeric powder capsules taken daily for three months has been reported to reduce agitation, anxiety and irritability in three people with severe Alzheimer's disease who were also taking an acetylcholinesterase inhibitor Nozomi, Ayu In a review of the evidence for curcumin and Alzheimer's disease, the researchers concluded that, to date, studies in people "have not been able to generate the anticipated benefits of curcumin," noting that this may be due, in part, to the low bioavailability and absorption of curcumin and the severity of disease progression in the people who participated Goozee, Br J Nutr Interestingly, in adults with insulin resistance, a bioavailability-enhanced form of curcumin appeared to cause a decrease in blood levels of amyloid-beta proteins see Insulin Resistance and Diabetes below.

Curcumin may help treat depression, although effects may take two to three months. A small but controlled, 8-week study among people with major depression found partial support for antidepressant and anti-anxiety effects of curcumin.

Patients received either placebo or curcumin mg of BCM twice daily and remained on pharmaceutical antidepressants during the study. At four weeks into treatment, depressive symptoms had improved equally for both groups, but from weeks 4 to 8 curcumin was significantly more effective than placebo in improving depressive symptoms.

Greater efficacy was noted among individuals with atypical depression. One of the ways curcumin may affect depression, according to the researchers, is through an immune-inflammatory pathway Lopresti, J Affect Disorders A larger, more recent study among people with major depression about half of whom were taking a prescription antidepressant found that a lower dose mg twice daily of BCM taken for three months significantly reduced symptoms of depression, as well as anxiety, compared to placebo, and was as effective as the higher dose of mg twice daily Lopresti, J Affect Disorders As in the previous study, curcumin's effects became significant compared to placebo after the first 4 weeks, and greater efficacy was found in those with atypical depression.

In addition, a study in Thailand showed that curcumin supplementation was more effective than placebo in improving symptoms of depression in adults who were already taking an antidepressant fluoxetine Prozac , sertraline Zoloft , trazodone Desyrel or mianserin Tolvon.

The curcumin was given as a capsule containing mg curcuminoids The dose was increased by mg per week for three weeks, and then maintained at a dose of 1, mg per day for eight more weeks. Compared to placebo, significant improvements in symptoms of depression occurred 12 weeks after beginning supplementation with curcumin Kanchanatawan, Neurotox Res In healthy people, curcumin may lessen increases in blood sugar and insulin after eating.

It may also decrease the risk of developing prediabetes in people who are overweight, and have modest benefits in people with insulin resistance or prediabetes. However, there is mixed evidence as to whether curcumin supplementation is beneficial in people with type 2 diabetes, and the effects may be very modest, at best.

Taking curcumin with a meal can minimize the increase in blood sugar and insulin levels that occurs after eating. Interestingly, taking the same amount of curcumin with fish oil 1. The same researchers subsequently conducted a 3-month study among 29 men and women average age 52 with insulin resistance.

They found that taking 1, mg of bioavailability-enhanced curcumin Meriva providing mg of curcumin daily, significantly reduced insulin resistance compared to placebo - 0.

a slight increase of 0. The curcumin also reduced blood serum levels of two compounds glycogen synthase kinase-3, known as GSK-3, and islet amyloid polypeptide, known as IAPP , which are associated with the development of both diabetes and Alzheimer's disease Thota, Nutrients However, in people with type 2 diabetes , curcumin supplementation appears to have only a slight benefit, at best.

A study in Japan among 33 men and women with impaired glucose tolerance or non-insulin dependent type 2 diabetes found that 90 mg of a bioavailability-enhanced curcumin formulation Theracurmin , Theravalues Inc.

taken twice daily after breakfast and dinner — a total of mg Theracurmin , providing 54 mg of curcumin per day for six months did not lower HbA1c a measure of blood sugar over time compared to placebo. Theravalues supplied the Theracurmin but did not fund the study Funamoto, J Diabetes Res Preliminary research shows that, taken over a longer period of time, curcumin may lower the chances of prediabetes blood sugar levels somewhat higher than normal advancing to actual diabetes.

A study of middle-aged, slightly overweight individuals in Thailand Chuengsamarn, Diabetes Care found that over nine months, none of the 97 subjects randomized to daily treatment with curcumin 1. Curcumin appeared to boost activity of the insulin-secreting cells in the pancreas. However, not all studies have found a benefit.

Studies showing a benefit were all conducted in Iran. These include a study using an "amorphous dispersion preparation" of curcumin Rahmani, Phytother Res and a study using a phytosomal formulation a complex of curcumin and soy phosphatidylcholine Meriva Panahi, Drug Res Stuttg More recent studies in Iran have used mg of curcumin with 5 mg of Bioperine C3 Complex , Sami Labs taken once daily by men and women with mild to moderate NAFLD.

In one such study, this was taken for three months, resulting in significantly decreased ALT, AST and ALP liver enzymes levels and disease severity scores, but no decrease in total or LDL cholesterol and no improvements in measures of blood sugar or insulin control compared to placebo Panahi, J Cell Biochem In another study, this was taken once daily for 12 weeks and significantly decreased ALT and AST liver enzymes, compared to placebo.

However, supplementation did not decrease liver fibrosis scarring Sharifi, Phytother Res In addition, supplementation did not improve most blood markers of liver inflammation, although there was a slight decrease in gamma glutamyltransferase GGT — elevated levels of which can indicate liver disfunction compared to placebo.

The researchers noted that participants were not required to fast before liver imaging using magnetic resonance spectroscopy, or MRS , which may have affected imaging results Hellmann, Diabetes Obes Metab Be aware that there are no long-term safety studies on the effects of curcumin supplementation on liver health.

A review of 11 randomized, placebo-controlled studies among adults with conditions such as pre-diabetes, obesity, metabolic syndrome, or non-alcoholic fatty acid liver disease concluded that curcumin had a modest but significant effect in reducing body weight and BMI body mass index.

On average, study participants lost 2. of bodyweight, based on studies tending to be 3 to 12 weeks in duration. Curcumin was also found to reduce waist circumference by about 1 to 1. Curcumin has been shown to suppress proliferation of a wide variety of cancer cell types in the laboratory, but research showing clear benefit in people is limited.

Test results indicated that this activity was achieved via absorption and circulation of curcumin through the blood stream, rather than direct effects of curcumin in the colon Carroll, Cancer Prev Res Phila However, it is unclear if this benefit reduces the percentage of patients who progress to myeloma compared to what occurs using the standard "watch and wait" strategy.

The curcumin used in this study was a "C3" curcuminoid mixture supplied by Sabinsa Corp. Each 4-gram dose provided 3, mg of curcumin, mg of desmethoxycurcumin, and 80 mg of bisdesmethoxycurcumin Golombick, Am J Hematol In another small study in people with myeloma, taking 4 and 8 grams of curcumin daily for up to one year significantly reduced levels of certain inflammatory markers such as COX-2 and a protein that promotes myeloma tumor growth NF-kB , although it did not result in clinical improvements Vadhan-Raj, Blood However, it has been reported that a year-old woman with stage 3 myeloma who was no longer responding to traditional treatment began taking a daily dose of 8 grams of curcumin with Bioperine dose not given and once-weekly hyperbaric oxygen therapy and, during the next five years up until the publication of the report , her myeloma remained stable with blood cell counts returning to normal range and maintaining a good quality of life Zaidi, BMJ Case Reports In a study of 21 patients with pancreatic cancer treated with 8 grams of curcumin daily, only two patients appeared to show a positive biological response i.

The curcumin used in this study provided the same ratio of curcumin, desmethoxycurcumin, and bisdesmethoxycurcumin as the Golombick study above Dhillon, Clin Cancer Res A study in France among 44 men with metastatic castration-resistant prostate cancer who were receiving chemotherapy docetaxel and glucocorticoids prednisone or prednisolone found that taking 6, mg of curcumin daily in divided doses taken in the morning, at lunchtime and in the evening for seven days starting four days before each three-day chemotherapy treatment for six months did not improve progression-free or overall survival, PSA response rate or quality of life compared to the same medical therapy plus a placebo Passildas-Jahanmohan, Cancer Med There is mixed evidence on whether turmeric and curcumin can lower cholesterol.

Curcumin formulations with enhanced bioavailability have generally shown better results than regular turmeric powder or curcumin. A review of studies failed to find a beneficial effect on cholesterol levels from turmeric or curcumin, although that review did not include studies of products with enhanced bioavailability Sahebkar, Clin Nutr In contrast, a later review, in , indicated that turmeric and curcumin can lead to modest improvements by lowering elevated LDL "bad" cholesterol and triglycerides — although they do not help raise HDL "good" cholesterol or lower total cholesterol levels.

Curcumin formulations with enhanced bioavailability seemed to be more effective than turmeric powder, particularly with regard to lowering triglycerides the review did not identify ideal dosage or formulations Qin, Nutr J Those who took only the curcumin had slight but non-significant decreases in total or LDL cholesterol Ferguson, Metabolism Adding turmeric to food has been shown to reduce the amount of salt needed to add a salty flavor.

Parsley also increased perceived saltiness, but not as much as turmeric. The effect of these spices on perceived saltiness was attributed to eugenol, an odorous compound found in all four spices Segura-Borrego, J Sci Food Agric A small study in Brazil among children and adolescents with persistent asthma of generally moderate severity who were taking traditional asthma medications found that daily supplementation with curcumin for six months decreased nighttime awakenings and use of short-acting inhalers, and improved disease control compared to traditional treatment plus a placebo.

The curcumin was given twice daily in capsules; each capsule contained mg of root powder including 11 mg of curcumin and 2 mg of demethoxycurcumin and the daily dose for each child varied by weight about 30 mg per kg of bodyweight per day. Approximate daily dosages by age were: mg powder 20 mg curcuminoids 7 - 10 yrs ; mg powder 30 mg curcuminoids 11 - 14 yrs , and 1, mg powder 40 mg curcuminoids 15 - 18 yrs Manarin, J Ethnopharmacol A pilot study suggests that curcumin can reduce nasal symptoms associated with seasonal allergy allergic rhinitis.

In this study, more than people in China with a history of seasonal allergy took capsules containing mg of curcumin ORGANIKA Health Products, Canada or a placebo colored starch daily for two months.

Over this period there were significant improvements in sneezing, runny nose, and nasal congestion among those given curcumin, with the average total symptom score falling from 8 out of a possible 12 down to 2.

Curcumin was also found to affect levels of certain inflammatory mediators, including decreases in interleukin-4 and TNF-alpha Wu, Ann Allergy Asthma Immunol Although preliminary studies suggest that curcumin may help people with chronic anterior uveitis an autoimmune disease of the eye that causes symptoms such as redness, pain, light sensitivity and blurred vision , this has not been proven in a well-controlled study.

The average number of relapses decreased from per year prior to supplementation to 36 during supplementation. However, there was no placebo group, so conclusions cannot be drawn from this study. The researchers noted that the results suggest curcumin might be beneficial for other inflammatory eye conditions such as dry eye Pia, Clin Ophthalmol Laboratory and animal studies also suggest a potential benefit for dry eye but, there are no published efficacy studies in people.

There are anecdotal reports of curcumin being given to treat psoriasis , an autoimmune disease. However, a clinical trial with a curcuminoid complex showed a low response rate Kurd, J Am Acad Dermatol, There has been interest in curcumin as a neuroprotective agent for Parkinson's disease based on its anti-inflammatory and antioxidant effects, which laboratory and animal studies have suggested might prevent the loss of dopamine-producing nerve cells that can eventually lead to Parkinson's disease symptoms such as tremor, stiffness, balance problems, and slowness of movement.

One small clinical study in healthy, sedentary postmenopausal women found that a daily dose of mg from six 25 mg pills of a branded curcumin ingredient Theracurmin , Theravalues Corporation , taken for 2 months significantly lowered systolic blood pressure , but not diastolic blood pressure, compared to placebo.

Akazawa, Nutr Res The decrease in systolic blood pressure about 5 points was similar to that measured in women who did not take curcumin but participated in an aerobic exercise program at least 3 days per week for the duration of the study. The study does not note whether the six pills were taken together or divided throughout the day, or if they were taken with food.

A dose of mg of turmeric containing There has been interest in curcumin to help prevent attacks of gout due to research suggesting that curcumin and its metabolites bind to and may inhibit xanthine oxidase, an enzyme involved in producing urate uric acid , which can form painful crystals in tissues Shen, Bioorg Med Chem Lett Other laboratory research has suggested that curcumin can inhibit a transporter involved in re-absorbing urate from the kidneys, which leads to urate being returned to the blood Ao, Bioorg Med Chem However, a study in Thailand among 39 people average age 55 with persistent hyperuricemia elevated urate in the blood found that taking mg of curcumin twice daily for 8 weeks did not reduce blood levels of urate or increase urinary excretion of urate compared to placebo, although both the curcumin and placebo groups showed a reduction in blood levels of urate compared to baseline Laboratory studies suggest curcumin may inhibit viruses such as influenza, hepatitis C and Zika by interfering with a virus's ability to bind to cells and replicate Mounce Antiviral Res ; Mathew, J Funct Foods In animal studies, injections of curcumin have been shown to protect the lungs from injury and infection, including viral-induced acute respiratory distress syndrome, possibly by reducing inflammatory cytokines and other mechanisms Almatroodi, Molecules ; Punithavathi, Br J Pharmacol ; Avasarala, PLoS One A small study among 10 children in Italy with recurrent respiratory infections found that a combination of curcumin mg and lactoferrin mg taken three times daily for four weeks had a beneficial effect on certain immune system cells Zuccotti, J Biol Regul Homeost Agents Among specific symptoms, Theracurmin Super reduced the number of days of sneezing Theracurmin did not reduce the number of days of any specific symptom.

No between group differences in immunity tests or inflammatory markers were observed, and blood levels of curcumin were not measured in this study.

Theracurmin is a crystalline form of curcumin with enhanced bioavailability due to its small particle size, and Theracurcumin Super is a non-crystalline form of curcumin mixed with a "dispersing agent" that is reportedly twice as bioavailable as Theracurmin Kuwabara, J Diet Suppl Preliminary evidence from a laboratory study suggested that curcumin may inhibit the virus that causes COVID Khaerunnisa, Preprints However, a small study in people conducted in Iran from November to April found little benefit.

There were no significant differences between groups in red and white blood cell counts, inflammation as measured by blood levels of CRP , or liver enzymes Askari, Trials Curcumin as BCM has been shown to reduce certain markers of chronic low-grade inflammation in obese cats Leray, Br J Nutr , but there are no studies of its effects in cats with osteoarthritis.

Recommended dosing of curcumin for dogs ranges from 50 mg to mg three times daily depending on the size of the animal or ½ teaspoon daily of whole turmeric twice daily, and, for cats, 50 mg to mg daily or ¼ teaspoon daily of whole turmeric Wynn, Veterinary Herbal Medicine Be aware that polysorbate 80, which may be included in some curcumin formulations for people can cause severe allergic reactions in some dogs Comblain, J Vet Pharmacol Ther However, no adverse effects were reported in dogs when black pepper extract, a bioavailability enhancer, was added to a food formulation containing curcumin and other ingredients Head, J Alzheimers Dis ; there do not appear to be such safety studies cats.

Unpleasant body odor in dogs taking curcumin has been reported Dejonckheere, British Association of Veterinary Herbalists Additional clinical studies of turmeric and curcumin in a variety of diseases are ongoing. Like other supplements, neither the FDA nor any other federal or state agency routinely tests turmeric supplements for quality prior to sale.

However, quality issues for turmeric supplements can include the following:. Heavy metal contamination above 0. Although traces of solvents which are used to make extracts were found in most products, none exceeded USP limits Skiba, Mol Nutr Food Res These findings support ConsumerLab's allocation of testing of herbal supplements: All products are tested for key compounds; all herb powders are tested for heavy metals; and solvent testing is generally not performed.

Radiocarbon testing indicated that four products Vitpro , Me First Living , Eagle , and Primal Harvest contained "fossil fuel derived organic carbon," possibly indicating synthetic curcumin. Two products B'Leaf Nature and Eagle were above California's Prop 65 limits for lead.

NOW also found animal gelatin in two products Bioganix and Nutriflair labeled as vegetarian capsules. NOW tested two of its own products, with which it reported finding no problems but noted that most of the other products were labeled as "Turmeric Curcumin mg," which could be deceiving, because they were formulas of mostly turmeric powder promising only 50 mg of curcuminoids from turmeric extract.

com's tests showed that the selected supplements contained the amounts of curcuminoids expected from their labels, but these amounts ranged from just Lead contamination was discovered in one product, Jamieson Curcumin Turmeric , and this was confirmed in a second independent laboratory.

The amount of lead per capsule was 1. The product is Canadian, but, if sold in California, this amount would require a statement on the label warning of possible reproductive harm the California limit is 0.

There is no limit in the rest of the U. The lead likely came from the mg of turmeric powder per capsule. ConsumerLab has found lead in other turmeric powders in the past. Lead contamination is not an issue in turmeric extracts , as the extraction process reduces impurities. All tablets broke apart properly to release their ingredients.

A total of 15 supplements and 3 spices were Approved for quality, including four supplements tested through ConsumerLab. com's voluntary Quality Certification Program. As shown above, three turmeric spice products were also tested -- all of which were Approved for quality — and each provided approximately 35 mg of curcuminoids per ½ level teaspoon.

Although none exceeded ConsumerLab's limits for heavy metal contamination, McCormick had slightly more lead than Frontier Co-Op organic , while Great Value Wal-Mart organic had the least lead.

It is interesting to note that, per gram of turmeric powder, all of these products contained less than one-quarter the concentration of lead found in the Jamieson supplement described above.

It is worth paying so much more? Usually not. Many of the higher cost supplements are special formulations that increase the absorption and bioavailablity of cucuminoids, but this benefit generally exists only if you take turmeric with only water.

If taken with a meal with fats or oils, these may offer no significant benefit over regular turmeric products. Other formulations that are more expensive are gummies, but the gummies from Spring Valley are not bioavailability-enhanced and don't seem to be worth the extra cost or the extra calories from the sugar they contain.

Interestingly, it is actually less expensive to get curcuminoids from ground turmeric spices than from some of the turmeric supplements. For example, a ½ teaspoon of Great Value Ground Turmeric costs about 9 cents and provides On the other hand, several of the turmeric extracts are much less expensive sources of curcuminoids than turmeric spice.

Examples are the supplements from Kirkland , Puritan's Pride , Root2 , GNC , and Life Extension. Among the supplements Approved in testing, our Top Pick Turmeric Supplement is Kirkland Costco Signature Turmeric mg , which provides the second highest amount of curcuminoids per daily suggested serving of any product mg per day from 2 vegetarian capsules at the lowest cost for curcuminoids.

A 2-capsule serving is only 28 cents. Root2 Turmeric Extract Curcumin C3 is similar to Kirkland with slightly more curcuminoids but with about half the amount of black pepper extract and at higher cost 50 cents per 2 capsules — it was a previous Top Pick in If you are not able to take a turmeric supplement with a fat-containing meal, it would be best to use one of the products with enhanced absorption and bioavailability.

Compared to taking an unformulated curcumin extract with water from which very little of the curcuminoids will be absorbed , some of these special formulations can increase bioavailability by more than times for details see " Absorption and Bioavailability ".

The formulation that has shown the greatest improvement in bioavailability over straight curcumin if taken without food is NovaSol , which is found in A1 Vitality Turmeric Curcumin , making it our Top Pick Turmeric Supplement If Taken Without Food.

It is expensive in comparison to other products based on the amount of curcuminoids it contains, but it should enable you to take a lot less extract than other products. For example, a two-softgel serving 83 cents of A1 Vitality contains only 60 mg of curcuminoids versus around 1, mg in Kirkland and Root2.

However, NovaSol was shown in one study to increase the bioavailability of curcumin 9-fold compared to the C3 formulation in Root2 , and by as much as fold compared to plain curcumin when these were taken with only water. For pets For pets, we tested one product, Zesty Paws Turmeric Curcumin Bites Multifunctional.

It contained the expected amount of curcuminoids, with each chew providing mg of curcuminoids — which is in line with recommended dosage for dogs , making it our Top Pick for dogs.

It includes black pepper extract to increase bioavailability. Black pepper is not listed as toxic to dogs by the ASPCA or American Veterinary Association, although the long-term safety of black pepper extract has not been evaluated in dogs.

com purchased three popular ground turmeric spices. Among these, Great Value Wal-Mart Ground Turmeric — Organic is our Top Pick Ground Turmeric Spice. Interestingly, the Great Value is somewhat denser than the other others, with a ½ level teaspoon weighing 1.

Note: In , we tested the same McCormick product against The Spice Hunter and Simply Organic and we found notably higher concentrations of curcuminoids in McCormick than in the others.

Below are two tables. The first displays test results for 16 turmeric or curcumin supplements. Twelve were selected for testing by ConsumerLab. com and four others each indicated with a CL flask are included for having passed the same testing through ConsumerLab.

Products listed as "Approved" met their label claim and ConsumerLab. com's standards for turmeric supplements. Shown in the 2 nd column are the amounts of curcuminoids claimed and found, while the amounts of heavy metals found in root powders is in the 3 rd column, along with pill size and serving suggestions.

The 4 th column shows the cost of the product and the cost to obtain mg of curcuminoids based on amount found. Notable features are in the 5 th column, and the full list of ingredients is in the last column.

The second table displays test results for three ground turmeric spices that were selected by ConsumerLab. com for testing. The ingredient description for each spice appears in the 2 nd column of the table.

Amounts of curcuminoids and heavy metals found are in the 3 rd column. Notable features are in the 4 th column, and cost comparisons are in the last column. Click arrows or swipe left or right to see all columns.

Unless otherwise noted, information about the products listed above is based on the samples purchased by ConsumerLab. com CL for this Product Review.

The samples are from a single lot of the respective product. Be aware that there may lot-to-lot variation in products, particularly natural products.

Manufacturers may change ingredients and label information at any time, so be sure to check labels carefully when evaluating the product you use or buy as it may be different from the product we tested.

Manufacturers may also change ingredient suppliers, which can affect product quality. The information contained in this report is based on the compilation and review of information from product labeling and analytic testing.

CL applies what it believes to be the most appropriate testing methods and standards. The information in this report does not reflect the opinion or recommendation of CL, its officers or employees. CL cannot assure the accuracy of information. Copyright ConsumerLab.

com, LLC, All rights reserved. Not to be reproduced, excerpted, or cited in any fashion without the express written permission of ConsumerLab. com LLC. Consumers should look for the following information on turmeric supplement labels:.

The FDA requires all of the above information to appear on labels. While it is preferable that the concentration of curcumin also be indicated, optimal doses of curcumin have not yet been established.

You may notice slight variation in the orange-yellow color of curcumin or turmeric from product-to-product and even from lot-to-lot for a specific product.

This is not necessarily a problem. What is most important is whether or not the product provides the correct amount of curcuminoid compounds as discussed above in "What CL Found".

Reasons for color variation include how the root powder or extract is prepared even roots used to make root powders are typically briefly boiled to help "set" the turmeric , seasonal and climatic variations in the regions from which the root is sourced, and a change in the ingredient supplier used by a manufacturer.

Clinical studies with turmeric root powder have generally used 3 to 12 grams 3, mg to 12, mg daily. However, the bulky volume of more than 8 grams per day may be unacceptable to some people. Appropriate doses depend on the form and concentration of turmeric used in the supplement.

The best way to take a curcumin or turmeric supplement is to take it twice a day because it has a half-life of just a couple of hours and, each time, to take it with a meal that contains some fat or oil.

The reason to take it with a fat-containing meal is that as discussed in the Absorption and Bioavailability section below standard curcumin has low bioavailability and only a small percentage of the curcumin if not bioavailability enhanced will be absorbed.

Most clinical studies of curcumin and turmeric use twice-daily dosing. Even products that contain bioavailability-enhanced formulations of curcumin are probably best taken twice daily and with a fatty meal to further boost absorption.

Be aware that you'll absorb little curcumin if adding turmeric or curcumin to tea or to a fruit or vegetable smoothie containing little fat. Diets high in the spice turmeric will contain about 60 to mg of curcumin per day, although doses used therapeutically are typically several times higher than this.

If you are cooking with turmeric spice , be aware that some curcumin may be lost due to heat or chemical changes during cooking. Note: Adding black pepper to turmeric-containing foods can increase the bioavailability of the curcumin and, as noted earlier, consuming such foods with as part of a fat-containing meal will help to increase curcumin absorption.

A small study found that, when mixed into a high-fat meal mashed potatoes with cream providing 40 grams of fat , the curcuminoids in turmeric powder 12 grams were about twice as bioavailable as those from freshly grated turmeric 83 grams.

The researchers speculated that compounds naturally in turmeric but not in curcumin powder, such as oils or starches, naturally enhance the absorption of curcuminoids Nasef, Food Funct In this Review, it is used in Root2 Turmeric Extract Curcumin C3 Complex.

Based on ConsumerLab. In addition, unformulated curcumin has a short half-life the amount of time it takes for blood levels to fall by half of two hours or less Suresh, CrystEngComm As curcumin is lipophilic it binds to fats , taking curcumin with foods containing fats or oils will enhance absorption as they stimulate the product of bile, which, in turn, aids the absorption of fats and lipophilic compounds like curcumin.

Bioavailability-Enhanced Formulations Due to its poor natural bioavailability, a variety of special formulations have been developed to improve the absorption, half-life, and bioavailability of curcumin when taken with only water. Any product labeled as containing one of these formulations is specially marked in the second column of the Results table above.

Many small studies have compared the bioavailability of these special formulations to determine how much curcumin, or it and its metabolites total curcuminoids , make it into the blood over time. Due to differences in how the studies were conducted, it is difficult to compare results across studies.

A subsequent clinical study in which a small number of men and women were given each of several formulations over time taken with only water and on an empty stomach found that the formulations that most increased curcumin bioavailability were those that increased the water solubility of curcumin as well as its incorporation into micelles tiny fat droplets absorbed through the intestine.

Two formulations that were shown to do this were micellar curcumin NovaSOL and gamma-cyclodextrin curcumin Cavacurmin , which respectively, had fold and fold greater bioavailability of curcumin compared to unformulated curcumin. Both of these formulations also improved curcumin stability during simulated gastric and intestinal digestion.

On the other hand, formulations that prevented the metabolism of curcumin i. Another comparison study of special formulations — all taken only with 8 oz. of water on an empty stomach — also found that NovaSOL had the highest bioavailability for total curcuminoids, followed by Turmipure GOLD from Naturex , Naturex standard extract, C3 Complex , and finally, Meriva.

However, when looking specifically at the bioavailability of only curcumin , the main curcuminoid compound, there were no significant differences between formulations. The study was funded by Naturex Fanca-Berthon, J Nutr It is not an ingredient in any of the products tested in this review, but is marketed in the U.

by Wellness Resources. Keep in mind that none of the comparison studies above involved taking supplements along with a high-fat meal — had they, it's possible that absorption rates across formulations would be more similar to one another as well as to unformulated curcumin.

More information about some of these formulations follows listed alphabetically follows. See the What It Does section for information about how these have been used for specific therapeutic uses :.

BCM reconstitutes curcuminoids with other components of turmeric such as turmeric oils. A small study showed the bioavailability of BCM to be about 7 times that of normal curcumin, and about 6 times that of a curcumin-lecithin-piperine complex Antony, Indian J Pharma Sciences BCM is found in products such as Terry Naturally CuraMed tested in this Review and others such as Curcumin Extreme and Life Extension Super Bio-Curcumin.

BCM is manufactured by Arjurna Natural Extracts, Inc. and distributed by DolCas Biotech in the U. Bioperine® Sabinsa Corporation is a patented black pepper extract containing the compound piperine, which inhibits the metabolism of curcumin in the gut and liver Shoba, Planta Med In contrast, only about 2.

Be aware that piperine may also significantly increase the absorption of other compounds, including certain medications See Cautions and Concerns. Black pepper extract and piperine are reported to have diuretic properties increasing urine output and stimulate the production of stomach acid Meghwal, Scientific Reports One animal study found lower doses of both black pepper extract and piperine to have a laxative effect, while higher doses were found to slow intestinal motility and have an antidiarrheal effect — although in these studies both doses were significantly higher than amounts found in curcumin supplements Mehmood, J Med Food In people, there do not appear to be any reported adverse effects when taken at typical doses; Bioperine® is self-affirmed GRAS generally recognized as safe FDA In this review, Bioperine is part of the C3 complex in the Root2 Turmeric Extract Curcumin C3 Complex and is included in Zesty Paws Turmeric Curcumin Bites.

Curcugen Olene Life Sciences Pvt. is a standardized curcumin formulation described as " Curcugen is sold as an ingredient in Wellness 26 CurcuOne with Curcugen. CurcuWin OmniActive Health Technologies combines curcumin with a hydrophilic carrier , making it more dispersible in water.

In the study, the supplements were taken with water on an empty stomach, putting standard curcumin at a great disadvantage since its absorption is enhanced when taken with a fatty oily meal.

One product in this review contains CurcuWin: Allergy Research Group CurcuWin However, as discussed above, it's not clear how this formula would compare with standard curcumin if both were taken with a fatty meal. CurQfen Akay Group combines curcumin with dietary fiber rich in galactomannans from fenugreek seed.

In a study funded by Akay Group among 50 healthy adults average age 33 who fasted overnight, 1, mg of CurQfen providing mg of curcuminoids had Curcuminoids from CurQfen also were found in the blood for a longer period 3.

Meriva Indena S. is a proprietary phytosomal combination of phosphatidylcholine-enriched soy lecithin and curcumin. Phytosome enhancers combine supplement ingredients with phosphatidylcholine, a natural surfactant that dissolves in both water and oil.

A study in rats showed a 5-fold increase in bioavailability with Meriva compared to curcumin and even greater increases in other curcuminoids Marczylo, Cancer Chemother Pharmacol A study in humans Cuomo, J Nat Prod also suggested increased absorption from Meriva. The small study showed a significant increase in plasma levels of curcumin metabolites -- although not of curcumin itself - from capsules of Meriva compared to capsules containing unformulated curcuminoids.

Trmeric respect your revlews. Turmeric supplement reviews email addresses you provide will reviewss used just for sending this ssupplement. To reviess understand what's inside botanical supplements, Turmeric supplement reviews Reports decided Turmeric supplement reviews put samples of two Turmeric supplement reviews used ones to the reviewa to determine their potency Maximize your athletic potential purity: turmeric sometimes referred reviewe or sold as supplemennt, which is one of its active compounds and echinacea. Inechinacea and turmeric were listed as the second and third most popular botanical supplements after horehound, an ingredient in Ricola cough drops in the annual market report from the American Botanical Council, a nonprofit group that supports herbal medicine. Echinacea is sold on its own, and it's also an ingredient in Airborne, an herbal blend that is claimed to fight colds. Between andsales of turmeric grew Of the 16 echinacea and 13 turmeric products we tested, we identified concerns with more than a third of them, including elevated levels of lead and bacteria, as well as low levels of key active compounds.