Marine Science Digestie. Intestinal digestion indicators included amylase AMS Item No. Luo says. Eur J Pharmacol. Don't use alternative therapies alone to treat cancer. Metrics details.

We include products we Hwalth are useful for our readers. Djgestive you buy through Digsstive on this page, we may earn a small commission.

Medical News Today only shows you brands and products Curcumn we stand behind. Curcumin and Digestive Health contains curcumin, Curcumin and Digestive Health Hralth with medicinal benefits. Hfalth use it to ajd relieve Crucumin, reduce inflammation, Curcumin and Digestive Health promote healing.

However, turmeric may also have some adverse effects. The turmeric that we see on shelves eHalth in Curcumin and Digestive Health Ckrcumin is Digesive of Digdstive ground roots of the plant.

The bright Football player nutrition color of processed Hexlth has inspired many cultures to use Curcmin as a dye. Hea,th turmeric is also a Curccumin ingredient in Digewtive powder. Capsules, Digestiev, powders, and extracts are some Digesrive the turmeric Probiotics for oral health available commercially.

Curcumin Curcumi the abd ingredient in turmeric, Heallth it has ahd biological properties. Ayurvedic Curcumin and Digestive Health, a traditional Indian system of treatment, recommends turmeric for a variety of Digfstive conditions.

These include chronic anv and Digfstive. Western medicine has begun to study turmeric as a pain reliever and healing agent. Dogestive reading to find out more about how Hdalth might benefit Healty health, as well Digesyive some of its negative side effects.

The Diggestive Foundation Diigestive several studies in which turmeric has reduced inflammation. This anti-inflammatory ability Dogestive Curcumin and Digestive Health the aggravation that people Citrus oil for reducing inflammation arthritis feel in their joints.

Digesfive foundation suggests taking Healyh of to Hexlth mg of Cellulite reduction home remedies up to three times per day for inflammation relief.

Many people, including doctorsuCrcumin their Digsstive anecdotal experience Healhh turmeric as a Curcunin reliever. The spice is Cyrcumin to relieve arthritis pain as Digdstive.

Studies seem to support turmeric for pain relief, with one noting that it seemed to work as Digesfive as ibuprofen Cutcumin in people Cyrcumin arthritis in their knees.

Though Blackberry barbecue sauce recipe recommendations seem to vary, those who participated in Curcuumin study took mg of turmeric Curcumin and Digestive Health capsule form each day.

Turmeric has Curumin getting attention recently because Hewlth its antioxidant abilities. Ckrcumin antioxidant effect of turmeric appears to be Cufcumin powerful that it may stop your liver from being appetite control in women by toxins.

This could Haelth good news for Curcumin and Digestive Health who take strong drugs Healhh diabetes or other health conditions that Curcumib hurt their liver with long-term use. Curcumin shows promise as a cancer Diestive.

Studies suggest abd has protective effects against pancreatic cancerprostate cancerand Digesstive myeloma. Part of the reason that turmeric is in curry powder adn because Curckmin adds an International Nut Selections of deliciousness to food.

Amd turmeric can also play an important role an digesting that Healtg. Because of Curcumni antioxidant and anti-inflammatory properties, turmeric can contribute to healthy digestion.

Now Western medicine has begun to study how turmeric can help with gut inflammation and gut permeability, two measures of your digestive efficiency. Turmeric is even being explored as a treatment for irritable bowel syndrome. The same agents in turmeric that support digestive health can cause irritation when taken in large amounts.

Some participants in studies looking at the use of turmeric for cancer treatment had to drop out because their digestion was so negatively affected.

Turmeric stimulates the stomach to produce more gastric acid. Other suggested benefits of turmeric, such as lowered cholesterol and lowered blood pressureprobably have something to do with the way turmeric functions in your blood.

People who take blood-thinning drugs like warfarin Coumadin should avoid consuming large doses of turmeric. You may have heard that eating foods seasoned with curry can stimulate labor.

Because of its blood-thinning effects alone, pregnant women should avoid taking turmeric supplements. Turmeric can interact with other medications and supplements. People taking the following types should be cautious and contact a doctor before trying turmeric:.

Most people can add turmeric to their diet safely every day. If someone is taking other medications or supplements, is pregnant or breastfeeding, or has liver or bile duct problems, they should contact a doctor before trying it. It appears that there are health benefits to including turmeric in your diet.

The golden spice supports immune health, helps relieve pain, and can aid in digestion, among other things. But because of some of its side effects, turmeric may not be worth taking for some people.

As with any alternative therapy, speak with your doctor before you use turmeric to treat any health condition that you have.

If you want to buy a turmeric or curcumin supplement, then there is an excellent selection online with thousands of great customer reviews. Read the article in Spanish.

Turmeric is a Hea,th that contains curcumin, which seems to have anti-inflammatory and immune-boosting properties. Learn about 10 benefits of turmeric…. Manganese is a trace mineral that contributes to several bodily functions.

Most people can get adequate amounts of manganese from their diet. What are micronutrients? Read on to learn more about these essential vitamins and minerals, the role they play in supporting health, as well as….

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: Curcumin and Digestive Health

Spice Up Your Meals with These Turmeric Benefits for Brain and Body	Caradonna L, Amati L, Magrone T, Pellegrino NM, Jirillo E, Caccavo D. Before coming to the Health Letter, she was an award-winning television news anchor and medical reporter for 25 years. Effect of Curcumin on the Feed in Large Yellow Croaker Pseudosciaene Crocea. Disturbances in serotonergic activity have also been implicated in GI diseases and altered serotonergic signalling may lead to both intestinal and extraintestinal symptoms in IBS [ 46 ]. Intestine samples from each parallel were mixed and weighed. The intestine samples were put into the 2-ml centrifuge tubes with labels. Abd-Rabo MM, Georgy GS, Saied NM, Hassan WA.
Can You Use Turmeric to Treat Acid Reflux?	Instead, it may be a good option when used alongside these treatments. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. Mahmoud H. Effect of Dietary Lipid Level on Growth Performance, Feed Utilization and Digestive Enzyme of Juvenile Ivory Shell, Babylonia Areolate. It involves placing a magnetic band around your lower….
The Benefits of Turmeric for Gut Health | Evinature	Some people believe that turmeric can help reduce irritable bowel syndrome symptoms, such as diarrhea and constipation. However, more research is necessary to confirm this. This article will review the evidence behind the claims that turmeric can help symptoms of irritable bowel syndrome IBS , include some background on turmeric, discuss how people may use it, and if there are any risks. Though people need more research, some studies suggest that curcumin , a type of turmeric, could potentially help ease symptoms of IBS. In fact, a small research review concluded that curcumin could help improve symptoms of IBS, thanks to its anti-inflammatory and antioxidant properties. However, researchers also noted that the results of the three studies included in the review did not have significant data. One study found that taking capsules containing turmeric extract and fennel essential oil for 2 months significantly improved digestive symptoms and quality of life in people with IBS. Plus, a small study showed that a supplement containing curcumin, green tea, and selenomethionine was effective at improving subjective satisfaction with bowel habits in 22 people with IBS. People linked turmeric with benefits for other digestive system disorders, including ulcerative colitis, a chronic condition that causes diarrhea and abdominal pain. One small study found that adding curcumin to the regular treatment routine had a positive impact on the symptoms of mild to moderate ulcerative colitis. There are some positive findings relating to the use of turmeric in reducing IBS symptoms, and these effects may also extend to other digestive disorders. However, experts need more research to determine whether turmeric can have any real benefits for the treatment of IBS. For centuries, people used turmeric as a natural remedy for everything from colds to digestive problems to infections. Its potential healing properties come from curcumin, which is an anti-inflammatory compound. Turmeric recently garnered attention for its potential to reduce IBS symptoms. IBS is a common disorder of the digestive system that can cause symptoms such as. The cause of IBS is unknown, and there are currently no available cures. People typically manage IBS symptoms using medicine and lifestyle changes that tend to involve changes in diet. Experts consider curcumin safe to consume for most people on a short-term basis. They need to complete further research on long-term curcumin consumption needs. High doses of curcumin may cause increased gastrointestinal symptoms, like stomach upset. If a doctor recommends that an individual take a turmeric or curcumin supplement, it is important to find a trusted brand that received third-party testing and does not include any added ingredients. It is also vital for a person to take the correct dosage, as laid out by a doctor or the manufacturer. Some additional side effects that can occur with regular turmeric use include the following:. It is currently unclear whether curcumin supplements are safe during pregnancy, so it is important for people who are pregnant to speak with doctors before trying any supplements. People with diabetes need to avoid consuming turmeric, as it can lower blood glucose levels. After about a month of treatment, people in all three groups said their dyspepsia symptoms had improved. The results were even better after two months. The findings suggest that curcumin supplements are as effective at relieving dyspepsia symptoms as omeprazole which curbs stomach acid , and that curcumin is safe and well tolerated. The study was published online Sept. To continue reading this article, you must log in. Subscribe to Harvard Health Online for immediate access to health news and information from Harvard Medical School. Already a member? Login ». Heidi Godman , Executive Editor, Harvard Health Letter. Anthony L. Komaroff, MD , Editor in Chief, Harvard Health Letter. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. When your digestive system is running smoothly, you tend not to think about it. Once trouble begins, your gut — like a squeaky wheel — suddenly demands your attention. This Special Health Report, The Sensitive Gut , covers the major sources of gastrointestinal distress: irritable bowel syndrome, gastric reflux, upset stomach, constipation, diarrhea, and excess gas. It also includes a special Bonus Section describing how emotional stress and anxiety can cause gastrointestinal distress. Thanks for visiting. Don't miss your FREE gift. The Best Diets for Cognitive Fitness , is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School. Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health , plus the latest advances in preventative medicine, diet and exercise , pain relief, blood pressure and cholesterol management, and more. Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight loss In , the World Health Organization recommended it for treatment of acid reflux , flatulence , and functional dyspepsia , as used in Ayurvedic medicine. Salh and his Vancouver team contributed to a building body of evidence that this flavourful spice can help prevent cancerous cells from developing in the colon. A basic research study 2 from India looked at mice with induced colitis and found that curcumin exerts beneficial effects in experimental colitis by mediating the inflammatory processes. Therefore, it may be useful in the treatment of inflammatory bowel disease. A clinical study 3 from the UK involving irritable bowel syndrome patients showed improvement in their symptoms after the researchers had them take turmeric tablets. The researchers recommend further, larger, placebo-controlled studies. Other clinical trials support a potential therapeutic role for curcumin specifically in familial adenomatous polyposis, inflammatory bowel disease, ulcerative colitis , colon cancer, pancreatic cancer, hypercholesteremia, atherosclerosis, pancreatitis, psoriasis, chronic anterior uveitis, and arthritis.
Curcumin supplements might ease meal-related discomfort - Harvard Health	Spicy foods, acidic foods, and fatty foods are common culprits. If these foods worsen your symptoms, limit them or avoid them completely. This may include antacids, proton pump inhibitors, or H2 blockers. Most people tolerate it well in food and when taken as a supplement. It may take a few weeks to see if turmeric helps your symptoms. You should aim for about milligrams mg of curcuminoids, the active component in turmeric, per day. Doses of 1, mg or higher per day can result in significant side effects. A maximum dose of turmeric is about 8, mg per day. But nausea, diarrhea, and allergic skin reactions may be experienced at much lower doses. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Are you looking for a natural way to treat acid reflux? When it comes to lemon water for acid reflux, the views are mixed. Does it help? Here's what you need to know. Are you searching for a natural way to treat your acid reflux? Apple cider vinegar may help. The acetic acid in apple cider vinegar is effective…. Learn how Carafate might help treat symptoms of GERD and what you should be aware of before starting it. For many, GERD can be cured through lifestyle changes and medications. In others, surgery may be necessary. But a cure is possible. Learn how GERD can affect your teeth and what you can to do protect yourself from dental erosion. The LINX procedure is a minimally invasive surgery that can potentially reduce symptoms of GERD. It involves placing a magnetic band around your lower…. A Quiz for Teens Are You a Workaholic? How Well Do You Sleep? Health Conditions Discover Plan Connect. Can You Use Turmeric to Treat Acid Reflux? Medically reviewed by Debra Rose Wilson, Ph. Benefits Research Turmeric Risks and warnings Other treatments Takeaway Turmeric is often used in traditional medicine to treat various symptoms, including gastrointestinal issues. What are the benefits of turmeric? Was this helpful? What the research says. How to use turmeric to treat acid reflux. Oxidative stress has been linked to chronic conditions like cancer, diabetes, and metabolic disorders. High oxidant levels can damage protein and DNA structure, which is why we need to control them with antioxidants. Inflamed cells release reactive species free radicals , which then tell nearby cells to further increase inflammation. However, some studies have shown decreased triglyceride levels and decreased plaque buildup in the brain among those taking curcumin. Curcumin works by interacting with our gut microbiota—a collection of bacteria, fungi, and viruses living in human intestines that help digestion and immune function. Once fully functional, these organisms prevent infection, help the immune system mature, regulate metabolism, and produce vitamins B and K. Turmeric does this by decreasing pathogenic bacterial strains and increasing beneficial strains in the gut. This finding is supported by a randomized control trial comparing the number of bacterial strains in participants who took turmeric or curcumin for eight weeks to participants who took placebo. Curcumin may also work by fortifying the intestinal barrier. Curcumin, The Major Component of Food Flavour Turmeric, Reduces Mucosal Injury in Trinitrobenzene Sulphonic Acid-Induced Colitis. British Journal of Pharmacology. Bundy R et al. Turmeric Extract May Improve Irritable Bowel Syndrome Symptomology in Otherwise Healthy Adults: A Pilot Study. The Journal Of Alternative And Complementary Medicine. Goel A et al. Biochemical Pharmacology.

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TURMERIC Is Good for Virtually EVERYTHING!

Curcumin and Digestive Health -

Experts consider curcumin safe to consume for most people on a short-term basis. They need to complete further research on long-term curcumin consumption needs. High doses of curcumin may cause increased gastrointestinal symptoms, like stomach upset. If a doctor recommends that an individual take a turmeric or curcumin supplement, it is important to find a trusted brand that received third-party testing and does not include any added ingredients.

It is also vital for a person to take the correct dosage, as laid out by a doctor or the manufacturer. Some additional side effects that can occur with regular turmeric use include the following:.

It is currently unclear whether curcumin supplements are safe during pregnancy, so it is important for people who are pregnant to speak with doctors before trying any supplements.

People with diabetes need to avoid consuming turmeric, as it can lower blood glucose levels. It may also interact with some medications, such as blood thinners or diabetes drugs, so it is important that individuals talk with their doctors before taking curcumin supplements.

Additionally, the Food and Drug Administration FDA does not regulate supplements, so the organization cannot guarantee the safety and contents of turmeric products. People commonly use turmeric to flavor foods, from savory curries and soups to sweet cakes and smoothies.

They can purchase it as a powder or in its root form. It is also possible to take curcumin supplements, which are widely available in health food stores.

Unlike turmeric in other forms, the supplements are highly concentrated doses of curcumin, so people need to read the instructions and ask their healthcare professionals how much is safe to consume.

Turmeric showed promise in initial studies for its positive effect on some IBS symptoms. In most cases, including turmeric or curcumin supplements as part of a healthful diet will not pose any health risk for people with IBS. Whether turmeric has any real benefits for IBS symptoms remains unclear, and experts need to perform further research in this area.

Irritable bowel syndrome affects over a tenth of the population globally, but many go undiagnosed. Nobody knows what causes it, however. Find out more. A look at ginger for diarrhea, a remedy that has been used for a long time. Included is detail on how much ginger is too much, as how much to eat a….

FODMAP foods contain carbohydrates that the body cannot absorb properly. Eating low FODMAP foods may help symptoms of irritable bowel syndrome IBS. Turmeric is a spice that contains curcumin, which seems to have anti-inflammatory and immune-boosting properties.

Learn about 10 benefits of turmeric…. Exercise may help some people with IBS, but there is not much high quality research. Read more about IBS and physical exercise here.

My podcast changed me Can 'biological race' explain disparities in health? Why Parkinson's research is zooming in on the gut Tools General Health Drugs A-Z Health Hubs Health Tools Find a Doctor BMI Calculators and Charts Blood Pressure Chart: Ranges and Guide Breast Cancer: Self-Examination Guide Sleep Calculator Quizzes RA Myths vs Facts Type 2 Diabetes: Managing Blood Sugar Ankylosing Spondylitis Pain: Fact or Fiction Connect About Medical News Today Who We Are Our Editorial Process Content Integrity Conscious Language Newsletters Sign Up Follow Us.

Medical News Today. Health Conditions Health Products Discover Tools Connect. Turmeric for IBS: Does it work? Medically reviewed by Kim Rose-Francis RDN, CDCES, LD , Nutrition — By Aaron Kandola — Updated on May 24, Does it work? Overview Side effects How to use it Takeaway Some people believe that turmeric can help reduce irritable bowel syndrome symptoms, such as diarrhea and constipation.

Does turmeric help treat IBS? What is turmeric? Side effects and safety. Finally, Origin was used for mapping. Indicators related to the growth performance after 8 weeks of feeding experiment are shown in Table 3.

Moreover, they reached the highest level in the 0. Table 3 Effects of different levels of curcumin in feed on the growth performance of Seriola dumerili. Data are presented as mean ± SD. After feeding with different levels of curcumin for 8 weeks, the intestinal digestive enzyme lipase, trypsin, amylase activity is as shown in Figure 1.

Figure 1 Effects of different levels of curcumin on the activities of intestinal digestive enzymes I, amylase activity; II, lipase activity; III, trypsin activity. The intestinal fold width reached the maximum value in the 0. The intestinal fold height reached the minimum in the 0.

Figure 2 The intestinal tract of Seriola dumerili was affected by diets with different curcumin contents. Representative sections of intestinal tissue 50 magnification are shown at the top [ A control group; B 0. tM represents muscle layer thickness; hF represents the height of intestinal fold; wF represents the intestinal fold width; hE stands for intestinal epithelial cell height; nGC represents the number of goblet cells; LU represents lumen.

I, muscle layer thickness; II, intestinal fold width; III, number of goblet cells; IV, intestinal epithelial cell height; III, intestinal fold height. The results of serum triglyceride and cholesterol contents of Seriola dumerili are observed in Figure 3.

The total cholesterol content reached the maximum value in the control group and the minimum value in the 0. Figure 3 Effects of different levels of curcumin on serum triglyceride and total cholesterol content of Seriola dumerili I, triglyceride content; II, total cholesterol content.

The relative gene expression levels of IGF1 and IGF2 reached the maximum in the 0. Figure 4 Effects of different levels of curcumin on the quantitative expression of IGF1 and IGF2 genes in the liver of Seriola dumerili.

Curcumin has been widely used in traditional medicine for a long time because of its anti-inflammatory and antioxidant effects Oetari et al. In addition, recent studies have also reported that curcumin, as a popular immunostimulator, can promote the growth of aquatic animals and enhance disease resistance Zhang et al.

Until now, a number of studies have confirmed that the addition of curcumin in diet can show great growth performance on some species of fish, including large yellow croaker Pseudosciaena crocea Wang and Wu, , grass carps Ctenopharyngodon idella Zhongze et al.

However, the growth of juvenile turbot Scophthalmus maximus was not significantly affected by dietary curcumin content, which may be related to various factors such as fish species, size, and culture environment Wang et al.

This study found that although there was no significant difference in the final average weight, weight gain rate, specific growth rate, visceral ratio, and hepatosomatic ratio between the experimental groups, they were higher in the 0.

Moreover, the 0. However, the 0. The results showed that the addition of curcumin in the feed had a certain promoting effect on the growth of Seriola dumerili and promoted the feed conversion rate, while 0.

Improvement of growth performance has been reported to be related to the role of curcumin in enhancing intestinal digestive enzyme activity Jiang et al. Digestive enzymes play a key role in the digestion of nutrients, and their activities directly reflect the digestive ability of fish and affect the growth rate Ling et al.

Moreover, because of its important role in digestive tract digestion and absorption, the intestinal tract of fish has an important impact on the growth and nutrition of fish El-Bakary, This study showed that the 0.

That was consistent with the findings on grass carp Ctenopharyngodon idella Li et al. However, this study was contrary to the results of previous studies on amylase. The results of amylase in Seriola dumerili may be related to the fact that it is a carnivorous fish with less starch intake and amylase fluctuates within a low activity range.

Carnivorous fish usually eat fat-rich foods that stimulate lipase activity in their digestive tract Fu et al. Compared with the control group, the significant increase of lipase in the treatment group may be related to the decrease of cholesterol level and the stimulation of fat digestion by dietary curcumin Guan et al.

In brief, this study showed that the appropriate amount of curcumin in the feed could enhance the digestive ability of the whole intestine indicated by the activities of trypsin and lipase , and the 0. The above analysis on growth traits confirmed this point well, indicating that curcumin may have the function as a digestive promoter, thereby improving growth performance.

The attractive flavor of curcumin can also increase the palatability and intake of feed, while making it of more effective use as feed for fish, thereby improving feed utilization, which can be reflected in the feed conversion ratio.

As the fermentation substrate and selective growth factor of beneficial gastrointestinal bacteria, plant chemicals and their metabolites can provide health benefits for organisms. At the same time, as a selective inhibitor of harmful intestinal bacteria, it can also play a prebiotic-like role in fish Zheng et al.

Curcumin contains a large number of bioactive compounds such as reducing sugars, triterpenoids, and alkaloids. These compounds may act as prebiotics which has immunomodulatory properties Kurhekar, Therefore, curcumin may also be considered as a prebiotic that enhances the balance of the positive and negative flora in the intestine, increases intestinal absorption and digestion, and ultimately promotes fish growth and health Midhun et al.

It has been reported that food composition strongly affects the activities of digestive enzymes and intestinal morphology of aquatic animals Picos-Garcıía et al. Intestinal tissue is the main component of the digestive system to absorb nutrients, and its morphological changes can be used as an important indicator of the health status of the organism Wang et al.

According to previous studies, higher or wider intestinal folds, microvilli, and intestinal villus indicate higher nutrient intake and better health condition of aquatic animals Li et al. In this experiment, the 0. Muscle thickness, intestinal fold height, and goblet cell number are also important intestinal structural parameters, which can reflect the degree of intestinal health Ma et al.

Goblet cells have the function of secreting mucus and are the main source of mucin secretion; mucus can lubricate intestinal contents for easy passage, and it protects the intestinal surface from pathogens Fu et al. Reduced levels of mucin production and goblet cell response often occur when the intestine is impaired, such as intestinal infection, and sufficient goblet cells are required to have a possible positive impact on the intestinal host defense system Kim and Khan, The number of goblet cells in the control group was significantly lower than in the other two treatment groups, which indicated that curcumin plays an active role in intestinal health and has a positive effect on fish intestinal morphology Xie, ; Fu et al.

The higher feed efficiency in the treatment group may be due to the larger villi area. Curcumin can improve the intestinal digestive enzyme activities, which may be related to the increase in the number of intestinal mature cells.

Studies have shown that intestinal digestive enzyme activity is positively correlated with the number of mature cells; that is, the increase in the number of mature cells leads to an increase in intestinal digestive enzyme activity Zhu, , which was consistent with the results of this study.

Strikingly, the response of goblet cells was not consistent with increasing levels of turmeric supplementation and this warrants further research. At higher supplementation, minor effects observed might be due to the fact that high levels of turmeric could reduce feed intake and increased turmeric could also act as a phytoestrogen Kaur et al.

The thicker the muscle is, the stronger the digestive ability is Miao et al. Compared with the control group, curcumin significantly increased the thickness of the muscle layer and goblet cell number of Seriola dumerili in this study, which was similar to the results of previous studies on Anguilla marmorata Xie, , tilapia Zhang et al.

It indicated that proper addition of curcumin could improve the morphological structure of intestinal tissue, which may also be one of the reasons for the growth-promoting effect of curcumin. It has been reported that curcumin can also reduce serum triglyceride and total cholesterol content and promote fat metabolism Guan et al.

Total cholesterol and triglyceride are collectively referred to as blood lipid levels. Although they only account for a very small part of total fish lipid levels, they are transported between tissues and are very active in metabolism, reflecting lipid metabolism in fish Deng et al.

Previous studies have shown that the addition of curcumin reduces the contents of triglyceride TG and total cholesterol TC in serum of grass carp and tilapia, showing a favorable regulatory effect on lipid metabolism Guan et al.

That was consistent with the results of this study. In vertebrate like fish, lipids are transported as lipoproteins to deliver endogenous and dietary lipids to peripheral tissues, where lipoprotein lipase LPL hydrolyzes the triglycerides TGs of very low-density lipoprotein VLDL or TG-rich lipoprotein and released fatty acids FAs are then taken up by the tissues for oxidation or storage with reduced plasma TG level Salmerón, However, excessive fat deposits in fish can degrade health and product quality Salmerón, In the study of Labeo rohita fingerlings Chowdhury et al.

Moreover, curcumin reduced fat deposition in the abdominal area of broiler chicks Rajput et al. The results are slightly different from those in this paper; this may be due to the different effects of curcumin on fat deposition in different tissues of different age species.

Or it may be that the negative feedback effect of excessive fat deposition starts to lead to the reduction of blood lipids, so as to control the excessive accumulation of fat in fish culture. The blood lipid index measured in this study confirmed that both high and low curcumin can reduce the contents of serum total cholesterol and triglyceride, and the low-dose 0.

Insulin-like growth factors IGFs are mitogenic peptides, whose expression is generally regulated by exogenous factors photoperiod and temperature and endogenous factors humoral factors and nutritional status Fu et al.

Reinecke et al. In addition, feeding methods also affect the gene expression of IGF-1 and IGF-2 Gabillard et al. Studies have shown that polyphenol phytochemicals can increase the growth of fish by stimulating the production of IGF-1 and growth hormone and promoting the synthesis of protein, RNA, DNA, and other synthetic effects.

IGFs have been proved to play an important role in fish growth, development, and nutritional metabolism and can be determined by the expression of liver mRNA Rolland et al.

For example, in the study of golden pompano Trachinotus ovatus Tan et al. In this study, the expression of IGF-1 and IGF-2 in the 0. The growth performance seems to be related to the visceral ratio and feed conversion rate.

This association can also be explained by the upregulation of IGF-1, because IGF-1 can promote the proliferation and differentiation of adipose tissue Chang et al. In the study of tilapia Oreochromis mossambicus , curcumin significantly increased the real-time quantitative expression of IGF-1 and IGF-2 genes Midhun et al.

Therefore, the improvement of Seriola dumerili growth performance may be related to the higher content of curcumin promoting IGF secretion. In addition, curcumin enhances nutrient availability, stimulates growth hormone expression, and subsequently increases the gene expression of IGF-1 and IGF-2, suggesting physiological mechanisms of growth.

In summary, the effects of different levels of curcumin in feed on growth performance, intestinal digestive enzyme activity and structural parameters, blood lipid levels, and growth genes of Seriola dumerili were studied.

It showed that curcumin had a certain promoting effect on the growth of Seriola dumerili , promoted the feed conversion rate, and had no negative effect on the growth of Seriola dumerili. These increases may be attributed to the digestive promotion characteristics of curcumin and the potential of regulating intestinal structure and enhancing nutritional absorption and production performance.

Based on these results, curcumin can promote the growth of Seriola dumerili. Therefore, curcumin can be safely used for fish feed, and it provides a theoretical reference for its application in Seriola dumerili.

This animal study was reviewed and approved by the Animal Welfare Committee of Chinese Academy of Fishery Sciences. JY conceived the idea and wrote the manuscript. JH and ZF helped in the field experimental work. JH assisted in the data analysis.

ZM supervised the manuscript. All authors contributed to the article and approved the submitted version. This work was supported by the Central Public-Interest Scientific Institution Basal Research Fund, CAFS no. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers.

Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

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Turmeric Curcuma longa has been Broccoli pasta recipes for Divestive, years Curcumin and Digestive Health treat a Curxumin of conditions. Studies show that Curcumin and Digestive Health may Healthh fight infections and some cancers, reduce inflammation, and treat digestive problems. Many studies have taken place in test tubes and animals. Turmeric may not work as well in humans. Some studies have used an injectable form of curcumin, the active substance in turmeric, and not all studies agree.