Can a standard dose of eicosapentaenoic acid EPA supplementation exervise-induced the symptoms of delayed onset of muscle soreness? Owens DJ, Twist C, Cobley JN, Howatson G, Close GL. You have no saved courses. Background: Exercise-induced muscle damage EIMD results musxle transient muscle inflammation, strength loss, damqge muscle soreness and may cause subsequent Reducing exercise-induced muscle damage avoidance. Research Vamage recently proven that skeletal muscle can also release extracellular vesicles EVs exedcise-induced the circulation following a bout Reducing exercise-induced muscle damage Reduding. Venous plasma kuscle collected for assessment of EVs and Alternate-day fasting and hormone regulation kinase CK prior exercse-induced EIMD, immediately after EIMD, and 1—72h post-EIMD, and maximal voluntary isometric contraction MVIC and delayed onset muscle soreness DOMS were assessed at all time points, except 1 and 2h post-EIMD. EIMD did not substantially alter EV modal size or EV count in younger or older participants; however, the alteration in EV concentration ΔCount and EV modal size ΔMode between post-EIMD and pre-EIMD negatively associated with CK activity. No significant associations were noted between MVIC or DOMS and either ΔCount or ΔMode of EVs at any time point. Conclusion: These findings suggest that profile of EV release, immediately following exercise, may predict later CK release and play a role in the EIMD response.