However, more research is needed to confirm this potential benefit. People with allergies should not supplement with quercetin unless directed to do so by their healthcare professional.

Quercetin has antibacterial and antiviral properties. Lab tests show that quercetin can inhibit the growth of many bacteria, including. Quercetin, along with other flavonoids, may help inhibit the growth of many viruses.

Diet plays an essential role in reducing the risk of cardiovascular diseases , such as heart disease and strokes. Because fruit and vegetables contain flavonoids, eating more may help reduce the risk of these diseases.

Research suggests that quercetin may help protect heart health by mitigating blood vessel dysfunction mitigating endothelial dysfunction, and reducing heart disease risk factors like high blood pressure and atherosclerosis.

According to a analysis , taking quercetin supplements could be an effective way to reduce blood pressure. Further research shows that people who were overweight and took a quercetin supplement of milligrams mg per day had lower levels of harmful cholesterol in their blood and reduced systolic blood pressure.

Systolic blood pressure measures the pressure in the blood vessels during a heartbeat. People can get quercetin through their diet by eating a range of fruit and vegetables daily.

Onions are amongst the richest sources of dietary flavonoids you can eat, providing Quercetin is available as a nutritional supplement, typically in doses of to mg daily. Supplements may also include other substances, such as bromelain or vitamin C, which may help the body absorb quercetin more effectively.

The natural antioxidants found in fruits and vegetables can be beneficial when consumed as part of a balanced and nutritious diet.

However, quercetin may interact with some medications, so people should ask their doctor before taking a supplement.

Quercetin is a flavonoid found in fruit and vegetables. It has a wide range of benefits, which people can get by including a variety of fruit and vegetables in their diet. Although many studies have found several potential benefits of quercetin, many have been animal or in vitro studies.

If people want to supplement their diet with quercetin, they should seek advice from a healthcare professional first. Free radicals are unstable atoms that can cause damage to cells and lead to illnesses and the aging process.

Exactly what impact do they have on the…. Dementia describes symptoms affecting memory and cognitive function.

Learn about both…. Eucalyptus leaves contain antioxidants and may help to reduce inflammation. For thousands of years, and throughout the world, preparations of…. What are micronutrients? Quercetin may enhance the effect of these drugs, increasing your risk for bleeding.

Anticoagulants include:. Test tube and animal studies suggest that quercetin may enhance the effects of doxorubicin and cisplatin, which are two chemotherapy medications used to treat cancer. In addition, some doctors believe taking antioxidants at the same time as chemotherapy can be harmful, while others believe it can be helpful.

In one study, combining quercetin with the anti-tumor drug doxorubicin, increased the drug's beneficial effects on breast cancer cells. In another, taking quercetin alongside cisplatin reduced the medicines' therapeutic effects in ovarian cancer cells. Talk to your oncologist before taking any supplements if you are undergoing chemotherapy.

Quercetin may interfere with the body's absorption of this drug, which is used to suppress the immune system. Since quercetin affects the liver, concomitant use with medications that are changed by the liver may alter how the body metabolizes these medications.

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Gaussian Gaussian, Inc. Cossi, M. New developments in the polarizable continuum model for quantum mechanical and classical calculations on molecules in solution. J Chem Phys. Download references. This work was supported by the foundation of Fujian China Educational Committee JZ and earmarked fund for China Agriculture Research System CARSKXJ7.

College of Bee Science, Fujian Agriculture and Forestry University, Fuzhou, , P. Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology Ministry of Education , Department of Chemistry, Tsinghua University, Beijing, , P.

You can also search for this author in PubMed Google Scholar. and R. designed the study; Y. conducted the experiments; Y. analyzed the data; Y. interpreted the results and wrote the manuscript. Correspondence to Da-Fu Chen.

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Zheng, YZ. Antioxidant Activity of Quercetin and Its Glucosides from Propolis: A Theoretical Study. Sci Rep 7 , Download citation. Received : 27 April Accepted : 05 July Published : 08 August Anyone you share the following link with will be able to read this content:.

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Download PDF. Subjects Computational chemistry Density functional theory. Abstract Among the multiple components of propolis, flavonoids contribute greatly to the antioxidant activities of propolis. Introduction From the medical aspect, protecting cell against the damage caused by oxidation is of great importance.

Results and Discussion Molecular descriptors The structure of quercetin and its different glucosides are present in Fig. Figure 1. The chemical structure and atom numbering for quercetin and its glucosides.

Full size image. Full size table. Figure 2. Figure 3. The energy and distribution of HOMO and LUMO for quercetin and its glucosides in the gas phase. Conclusions In this work, the antioxidative properties of quercetin and its glucosides in the gas, ethanol and water phases were studied from theoretical aspect.

Methods Computational details Molecular descriptive parameters The molecular descriptive parameters including the electronegativity χ , IP, electron affinity EA , chemical hardness η , softness S , and electrophilicity index ω 39 are very vital to characterize the antioxidant property of flavonoids.

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Author information Authors and Affiliations College of Bee Science, Fujian Agriculture and Forestry University, Fuzhou, , P. China Geng Deng Authors Yan-Zhen Zheng View author publications. View author publications. Ethics declarations Competing Interests The authors declare that they have no competing interests.

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