Prescription weight loss pills -
If you've lost enough weight to improve your health and you haven't had serious side effects, your health care provider may suggest that you take the drug long term.
They may switch you to a different weight-loss drug. Six weight-loss drugs have been approved by the U. Food and Drug Administration FDA for long-term use:.
Most prescription weight-loss drugs work by making you feel less hungry or fuller. Some do both. The exception is orlistat. It affects the way your body absorbs fat. Bupropion-naltrexone is a combination drug.
Naltrexone is used to treat alcohol and opioid addiction. Bupropion is a drug to treat depression, called an antidepressant, and a drug to help people stop smoking, called a quit-smoking aid.
Like all antidepressants, bupropion carries a warning about suicide risk. Bupropion-naltrexone can raise blood pressure.
So your provider will need to check your blood pressure regularly at the start of treatment. Common side effects include nausea, headache and constipation. Liraglutide also is used to manage diabetes.
It's given as a daily shot. Nausea is a common complaint. Vomiting may limit its use. You also can get orlistat in a reduced-strength form without a prescription Alli.
Orlistat can cause side effects such as passing gas and having loose stools. You need to follow a low-fat diet when taking this medicine.
In rare cases, people have had serious liver injury with orlistat. But researchers haven't found that the drug causes liver injuries. Phentermine-topiramate is a combination of a weight-loss drug called phentermine and an anticonvulsant called topiramate.
Phentermine has the potential to be misused because it acts like a stimulant drug called an amphetamine. Other possible side effects include an increase in heart rate and blood pressure, insomnia, constipation, and nervousness. Topiramate increases the risk of birth defects.
Phentermine by itself Adipex-P, Lomaira also is used for weight loss. It's one of four similar weight-loss drugs approved for use for less than 12 weeks, called short-term use. The other drugs in this group aren't often prescribed. Semaglutide also is used to help control type 2 diabetes.
You take it as a weekly shot to manage obesity. The FDA has approved setmelanotide only for people age 6 and older who have obesity due to one of these rare inherited conditions:.
To take the drug, you'll need to have test results that show you have one of these conditions. Setmelanotide doesn't treat any of the gene problems that cause these conditions. But it can help you lose weight. It can lessen your appetite and make you feel fuller. And it may help you burn calories while your body is at rest.
Never give setmelanotide to a child under 6 years old. It can cause newborns and babies to have dangerous reactions.
Weight-loss drugs aren't an easy answer to weight loss. But they may help you make the lifestyle changes that you need to practice to lose weight and improve your health.
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You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Side effects: Orlistat often causes digestive issues like loose or oily stools, gas, and frequent bowel movements, making the medication difficult for some people to tolerate.
It could also contribute to nutrient deficiencies, including in fat-soluble vitamins A, D, E, or K. Following a low fat diet is typically recommended while taking this medication to help minimize adverse side effects.
Contraindications: chronic malabsorption, cholestasis a type of liver disease , pregnancy, renal impairment, and current use of certain prescription medications.
It requires a prescription from a doctor and is sold under the brand Qsymia. How it works: This medication includes phentermine , a central nervous system stimulant and appetite suppressant with similar mechanisms to amphetamine. It also includes topiramate , an anticonvulsant that helps reduce appetite and enhance satiety feeling full to promote weight loss.
It could also cause increased body temperature, an inability to sweat, and psychiatric or cognitive disturbances. Contraindications: This medication is not recommended for people with glaucoma eye conditions that can lead to blindness , a history of hyperthyroidism, pregnancy, recent use of monoamine oxidase inhibitors, and current use of certain prescription medications.
This medication, sold under the name Contrave, is an oral medication that combines bupropion, an antidepressant, and naltrexone, which is used to manage opioid or alcohol use disorder.
A doctor can determine whether Contrave may be a good option for you and then provide a prescription. Some online services may also prescribe Contrave following a virtual consultation with a healthcare professional.
Over 1 year, participants lost an average of 11—22 lb 5—9 kg. It might also increase heart rate and blood pressure. Contraindications: This medication is not recommended for people with a history of seizures, end-stage renal disease, pregnancy, and current use of monoamine oxidase inhibitors, opioids, or certain other prescription medications.
Setmelanotide, sold as Imcivree, is in a class of medications known as melanocortin 4 MC4 receptor agonists. How it works: People with specific genetic mutations may experience insufficient activation of the MC4 receptor in the brain, which could contribute to obesity. Setmelanotide works by increasing the activation of this receptor, leading to reduced hunger, decreased calorie intake, and increased metabolism , all of which could promote weight loss.
Participants also experienced a significant reduction in hunger with no serious treatment-related adverse events reported.
Another small study in children, adolescents, and adults found that setmelanotide significantly improved quality of life as early as 5 weeks after starting treatment, which could be related to reduced hunger and body weight. Side effects: Some of the most common side effects of setmelanotide include injection site reactions, hyperpigmentation , nausea, headache, diarrhea, and stomach or back pain.
Fatigue, vomiting, and depression have also been reported. Contraindications: This medication is not recommended for people with renal impairment, and those who are pregnant or breastfeeding.
There are several anorectics, or appetite suppressants , available. However, phentermine Adipex-P or Lomaira is the most commonly prescribed. Phentermine is taken orally and requires a prescription from a doctor or other healthcare professional.
How it works: These medications reduce appetite by altering levels of certain neurotransmitters in the brain, which can lead to weight loss. Effectiveness: One study in 3, people compared the effectiveness of several medications for obesity and found that people taking phentermine lost the highest percentage of body weight over 12 weeks.
Those taking phentermine lost an average of 8. However, keep in mind that these medications are only recommended for short-term use, as you can build up a tolerance after several weeks, resulting in decreased effectiveness. Side effects: Potential side effects may include nausea, vomiting, diarrhea, and stomach cramps.
Other severe side effects have been reported and require immediate medical attention, including shortness of breath, chest pain, and swelling of the lower extremities.
Contraindications: This medication is not recommended for people with a history of heart disease, hypertension, hyperthyroidism, glaucoma, diabetes, pregnancy, and certain prescription medications.
Most weight loss medications are approved for adults with obesity or overweight and at least one weight-related condition, such as:.
Similarly, setmelanotide Imcivree , is intended to treat obesity caused by certain genetic disorders. Keep in mind that weight loss medications are not suitable for everyone, including people who are pregnant, those with certain health conditions, or individuals taking specific medications.
A healthcare professional can provide guidance on whether you might be a candidate for a prescription, depending on your personal goals, medical history, and health status. Contact a trusted healthcare professional, like your OB-GYN, before taking any weight loss medications or supplements.
Some digital weight loss platforms, including Ro and Calibrate, include GLP-1 medications in their treatment plans for people who meet certain eligibility criteria. You can read our comprehensive reviews of Calibrate and Ro Health to learn more. Studies also suggest that people with higher body weights are disproportionately more likely to experience disordered eating and eating disorder symptoms.
These behaviors may indicate a disordered relationship with food or an ED. Disordered eating and EDs can affect anyone, regardless of gender identity, race, age, body size, socioeconomic status, or other identities.
They can be caused by any combination of biological, social, cultural, and environmental factors — not just by exposure to diet culture. GLP-1 agonists are currently the most effective anti-obesity medications and are considered safe for long-term use.
Currently, only liraglutide Saxenda , semaglutide Wegovy , and tirzepatide Zepbound are approved for weight loss, though some other GLP-1 drugs may be prescribed off-label.
Still, keep in mind that individual results can vary based on many factors, including your diet, health status, and activity level. In addition to maximizing your potential results, it can increase the likelihood of maintaining weight loss in the long term.
If considered medically necessary, insurance companies may cover certain prescription weight loss medications. Some manufacturers also offer savings cards, which can help lower your copay. Ozempic and Wegovy are two different brands of the same drug, semaglutide. If you are a Mayo Clinic patient, this could include protected health information.
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Show references Perreault L. Obesity in adults: Drug therapy. Accessed Oct. Won Son J, et al. Comprehensive review of current and upcoming anti-obesity drugs. Burguera B, et al. Mayo Clinic Proceedings. IBM Micromedex. Tak YJ, et al. Long-term efficacy and safety of anti-obesity treatment: Where do we stand?
Current Obesity Reports.
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If you have lost enough weight to improve your health and are not experiencing serious side effects, your health care professional may advise you to stay on the medication indefinitely.
Your health care professional may also. Because obesity is a chronic disease, you may need to continue your new eating and physical activity habits and other behaviors for years—or even a lifetime—to improve your health and maintain a healthier weight.
You probably will regain some weight after you stop taking weight management medication. Developing and maintaining healthy eating habits and increasing physical activity may help you regain less weight or keep it off. Federal physical activity guidelines PDF, You may need to do more than minutes of moderate-intensity activity a week to reach or maintain your weight-loss goal.
Some, but not all, insurance plans cover medications that treat overweight and obesity. Contact your insurance provider to find out if your plan covers these medications. The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat Xenical, Alliphentermine-topiramate Qsymianaltrexone-bupropion Contraveliraglutide Saxendaand semaglutide Wegovy —for long-term use.
A sixth approved drug, setmelanotide IMCIVREEis limited to people who have been diagnosed with one of three specific rare genetic disorders, which must be confirmed by genetic testing. You can keep taking these medications as long as you are benefiting from treatment and not experiencing serious side effects.
Some weight management medications that curb appetite are approved by the FDA for short-term use only, for up to 12 weeks. Although some health care professionals prescribe them for longer periods, not many research studies have looked at how safe and effective they are for long-term use.
Never take weight management medications if you are pregnant. If you are planning to get pregnant, you should also avoid these medications, as some of them may harm the fetus. By choosing an off-label medication to treat overweight and obesity, your health care professional may prescribe.
You should feel comfortable asking whether your health care professional is prescribing a medication that is not approved for treating overweight and obesity.
Before using a medication, learn all you need to know about it. Researchers are currently studying several new medications and combinations of medications in animals and people. Researchers are working to identify safer and more effective medications to help people who are overweight or have obesity lose weight and maintain a healthy weight for a long time.
NIDDK conducts and supports clinical trials in many diseases and conditions, including overweight and obesity. The trials look to find new ways to prevent, detect, or treat disease and improve quality of life.
Clinical trials—and other types of clinical studies —are part of medical research and involve people like you. When you volunteer to take part in a clinical study, you help doctors and researchers learn more about disease and improve health care for people in the future.
Researchers are studying many aspects of prescription medications to treat overweight or obesity, such a. Find out if clinical studies are right for you. Watch a video of NIDDK Director Dr. Griffin P. Rodgers explaining the importance of participating in clinical trials.
You can view a filtered list of clinical studies on prescription medications to treat overweight and obesity that are federally funded, open, and recruiting at www. You can expand or narrow the list to include clinical studies from industry, universities, and individuals; however, the National Institutes of Health does not review these studies and cannot ensure they are safe.
Always talk with your health care provider before you participate in a clinical study. This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases NIDDKpart of the National Institutes of Health. NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public.
Content produced by NIDDK is carefully reviewed by NIDDK scientists and other experts. NIDDK would like to thank: Kishore Gadde, M. English English Español. Weight Management Binge Eating Disorder Show child pages.
Tips to Help You Get Active Show child pages. Weight-loss Metabolic and Bariatric Surgery Show child pages. On this page: What are overweight and obesity? How common are overweight and obesity? How do weight management medications work? Who might benefit from weight management medications? Can children or teenagers take weight management medications?
Can medications replace physical activity and healthy eating habits as a way to lose weight? What are the benefits of using prescription medications to lose weight?
What are the concerns about using prescription medications to lose weight? Which weight management medication might work for me? How long will I need to take weight management medication?
Will I regain some weight after I stop taking weight management medication? Will insurance cover the cost of weight management medication? What medications are available to treat overweight and obesity?
What other medications for weight loss may be available in the future? Clinical Trials for Prescription Medications to Treat Overweight and Obesity What are overweight and obesity?
Buy your medication from a pharmacy or online distributor approved by your health care professional. Only take weight management medication to support your healthy eating and physical activity program. Know the side effects and warnings before taking any medication.
If you are not losing weight after 12 weeks on the full dose of your medication, ask your health care professional whether you should stop taking it. Talk with your health care professional about any other medications you are taking, including supplements and vitamins, when considering weight management medications.
Never take weight management medications during pregnancy or if you are planning a pregnancy. Your health care professional may also change your treatment plan or consider using a different weight management medication have you try different lifestyle, physical activity, or eating programs change your other medications that might be causing weight gain refer you to a bariatric surgeon to see if weight-loss bariatric surgery might be an option for you Because obesity is a chronic disease, you may need to continue your new eating and physical activity habits and other behaviors for years—or even a lifetime—to improve your health and maintain a healthier weight.
By choosing an off-label medication to treat overweight and obesity, your health care professional may prescribe a drug approved for treating a different medical problem two or more drugs at the same time a drug for a longer time period than approved by the FDA You should feel comfortable asking whether your health care professional is prescribing a medication that is not approved for treating overweight and obesity.
Future drugs may use new strategies, such as regulating several gut hormones at the same time targeting specific genes that cause obesity allowing people to lose body fat without losing muscle during weight loss changing bacteria in the gut to control weight Clinical Trials for Prescription Medications to Treat Overweight and Obesity NIDDK conducts and supports clinical trials in many diseases and conditions, including overweight and obesity.
: Prescription weight loss pills| Important Safety Information | A BMI of 27 or more and you have a disease or condition that may be related to your weight this could include diabetes or high blood pressure. How it works: These medications reduce appetite by altering levels of certain neurotransmitters in the brain, which can lead to weight loss. However, experts recommend that people avoid using Ozempic for weight loss since it's meant for people with type 2 diabetes. To continue reading this article, you must log in. Possible side effects vary by medication and how it acts on your body. Won Son J, et al. Admissions Requirements. |
| U.S. Food and Drug Administration | Other possible side effects include an increase in heart rate and blood pressure, insomnia, constipation, and nervousness. Topiramate increases the risk of birth defects. Phentermine by itself Adipex-P, Lomaira also is used for weight loss. It's one of four similar weight-loss drugs approved for use for less than 12 weeks, called short-term use. The other drugs in this group aren't often prescribed. Semaglutide also is used to help control type 2 diabetes. You take it as a weekly shot to manage obesity. The FDA has approved setmelanotide only for people age 6 and older who have obesity due to one of these rare inherited conditions:. To take the drug, you'll need to have test results that show you have one of these conditions. Setmelanotide doesn't treat any of the gene problems that cause these conditions. But it can help you lose weight. It can lessen your appetite and make you feel fuller. And it may help you burn calories while your body is at rest. Never give setmelanotide to a child under 6 years old. It can cause newborns and babies to have dangerous reactions. Weight-loss drugs aren't an easy answer to weight loss. But they may help you make the lifestyle changes that you need to practice to lose weight and improve your health. There is a problem with information submitted for this request. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview. Error Email field is required. Error Include a valid email address. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. This content does not have an English version. This content does not have an Arabic version. Appointments at Mayo Clinic Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Request Appointment. Healthy Lifestyle Weight loss. Sections Basics Weight-loss basics Diet plans The Mayo Clinic Diet Diet and exercise Diet pills, supplements and surgery In-Depth Expert Answers Multimedia Resources News From Mayo Clinic What's New. Products and services. Prescription weight-loss drugs Study the pros and cons of medicines to treat obesity. By Mayo Clinic Staff. Thank you for subscribing! Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. Show references AskMayoExpert. Weight management adult. Mayo Clinic; Obesity adult. Pilitsi E, et al. Pharmacotherapy of obesity: Available medications and drugs under investigation. Perreault L. Obesity in adults: Drug therapy. Accessed Oct. Prescription medications to treat overweight and obesity. National Institute of Diabetes and Digestive and Kidney Diseases. Accessed Aug. Melmed S, et al. In: Williams Textbook of Endocrinology. Elsevier; Patel K. Obesity treatment: A focus on pharmacotherapy of weight management. Papadakis MA, et al. McGraw Hill; Shah M expert opinion. Mayo Clinic. Apovian CM, et al. Pharmacological management of obesity: An Endocrine Society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism. Food and Drug Administration. Wegovy prescribing information. Novo Nordisk; Imcivree prescribing information. Rhythm Pharmaceuticals; Products and Services The Mayo Clinic Diet Online A Book: The Mayo Clinic Diet Bundle. Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Mayo Clinic on Incontinence - Mayo Clinic Press Mayo Clinic on Incontinence The Essential Diabetes Book - Mayo Clinic Press The Essential Diabetes Book Mayo Clinic on Hearing and Balance - Mayo Clinic Press Mayo Clinic on Hearing and Balance FREE Mayo Clinic Diet Assessment - Mayo Clinic Press FREE Mayo Clinic Diet Assessment Mayo Clinic Health Letter - FREE book - Mayo Clinic Press Mayo Clinic Health Letter - FREE book. ART Healthy Lifestyle Weight loss In-Depth Prescription weight-loss drugs. Show the heart some love! Give Today. Help us advance cardiovascular medicine. Find a doctor. Explore careers. A BMI of is considered overweight. A BMI of more than 30 is categorized as obesity. Use this calculator to learn your BMI. Like any medical condition, there are different ways to manage obesity. This can include many different weight-loss medications, like Wegovy. If you're trying to lose weight, our experts offer advice on when it's the right time to start a medication. There are many types of prescription weight-loss medicines that work differently to help with weight loss. Some are for short-term use less than 12 weeks. Some can be used for longer periods of time. Many weight loss medications have side effects. Learn about the causes of obesity, including physical activity, eating habits and sleep. FDA guidelines recommend that weight-loss medicines may be considered for people who have tried lifestyle changes and meet one or more of the following conditions:. It's important for you to talk to your doctor about the risks and benefits of all weight-loss treatments. Weight-loss medications may not be the right treatment for everyone. Make sure your doctor knows your full medical history. Always talk to your doctor before starting or stopping any medicine. Any weight-loss medicine should be taken along with lifestyle changes, such as exercise and a healthy diet — not in place of them. Read more: What is primary care? Learn why you should partner with a provider for your health from UC Davis Health. Wegovy is a popular weight-loss medication made by the same company as Ozempic , which has been in the news a lot recently. Wegovy is a weekly injection approved by the U. Food and Drug Administration FDA in for long-term weight management. It's the first drug approved for this purpose since Both Wegovy and Ozempic include the same active ingredient semaglutide. However, Ozempic has lower doses of semaglutide and was developed for people with type 2 diabetes. Wegovy contains higher doses of semaglutide and was formatted to help with weight loss. It's become a popular trend: taking Ozempic for weight loss. It's a once-weekly injection that was approved by the FDA for use in adults with type 2 diabetes. Ozempic is not approved for weight loss. However, semaglutide is approved for weight loss under the brand name Wegovy. Ozempic can help people lose weight. However, experts recommend that people avoid using Ozempic for weight loss since it's meant for people with type 2 diabetes. |
| Understanding new weight-loss drugs | What should I know about storage and disposal of this medication? This medicine could cause birth defects. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Phentermine and topiramate must be used along with a reduced calorie diet and exercise plan. You will still be protected from pregnancy if you are spotting, but you can talk to your doctor about other forms of birth control if the spotting is bothersome. When used in addition to lifestyle interventions, 2. Weight loss medications, sometimes also called weight loss drugs or anti-obesity medications, are prescription drugs that reduce your appetite and food cravings. |
| Phentermine and Topiramate: MedlinePlus Drug Information | Your health care professional may also change your treatment plan or consider using a different weight management medication have you try different lifestyle, physical activity, or eating programs change your other medications that might be causing weight gain refer you to a bariatric surgeon to see if weight-loss bariatric surgery might be an option for you Because obesity is a chronic disease, you may need to continue your new eating and physical activity habits and other behaviors for years—or even a lifetime—to improve your health and maintain a healthier weight. Your health care professional can assess your individual risk caused by your weight. In case of overdose, call the poison control helpline at Sherman MM, Ungureanu S, Rey JA. This progression can help to alleviate side effects, which include gastrointestinal symptoms, headache, dizziness, and fatigue. |
Prescrription Clinic Prescription weight loss pills Green tea weight loss in Arizona, Florida and Minnesota and at Mayo Clinic Meal frequency System locations. Are you Prescriptkon adult who has serious health problems because of your weight? Have RPescription tried diet and exercise but haven't been able to lose enough weight? If you answered yes to these questions, a prescription weight-loss drug may be a choice for you. Prescription drugs are medicines that a health care provider prescribes for you. You can't buy them off the shelf in a drug store like you can buy nonprescription medicines. Just know that you need to use prescription weight-loss drugs in addition to — not instead of — a healthy diet and exercise.
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