Boston, MA: American Botanical Council, Preventiion supplementation reduces pain and Organic holistic wellness and Dairy alternative products physical function in adults with Preventoon osteoarthritis. Effects of pycnogenol treatment on oxidative stress in PPycnogenol diabetic rats. A Double-Blind, Cross-Over Study to Examine the Effects of Maritime Pine Extract on Exercise Performance and Postexercise Inflammation, Oxidative Stress, Muscle Soreness, and Damage. Protective mechanisms of pycnogenol in ethanol-insulted cerebellar granule cells. Kim, et al. Screening is usually guided by age, family history and other factors, such as a past fracture or cancer treatment.

Pycnogenol and osteoporosis prevention -

Older individuals are at greater risk for deficiency because aging lowers the amount of 7-dehydrochlesterol in the skin and thus lowers the ability to produce vitamin D, as well as lower absorption.

Most of our vitamin D comes […]. Posted in Bone Loss , Menopause , Phytoestrogen on Dec 11th, This randomized, double-blind, placebo-controlled trial was conducted at three medical centers in Italy.

Bone density at the femoral neck and lumbar spine was tested after 24 months along with serum levels of bone-specific alkaline phosphatase, markers […]. Posted in Bone Health , Bone Loss , Breast Cancer Prevention , Calcium , General , Prevention , Vitamin D on Nov 25th, In a population-based study, Caucasian women older than 55, were randomized to receive a daily placebo, calcium or calcium plus IU of vitamin D cholecalciferol.

 Health status and compliance to the regimen were assessed every 6 months over 4 years and serum vitamin D was measured at baseline and annually. Posted in Bone Loss , General , Menopause , Phytoestrogen on Sep 27th, Bone densities at the femoral neck and lumbar spine were tested after 24 months along with serum levels of bone-specific alkaline phosphatase, […].

Home About Tori Hudson, N. Tori Hudson, N. Naturopathic Physician, Author, Educator and Researcher. Category Archive for 'Bone Loss' Soy Isoflavones Improve Bone Density and Menopausal Symptoms Posted in Bone Health , Bone Loss , Dietary Supplements , General , Menopause , Phytoestrogen , Soy on Apr 25th, Chinese menopausal […] Read Full Post ».

Calcium: How much do we need??? Examples of this include the following summaries: 1 Calcium from food does not appear to raise the risk of cardiovascular […] Read Full Post ». Pine Bark Extract Pycnogenol and osteoarthritis of the knee Posted in Bone Health , Bone Loss , Osteoarthtritis on Oct 23rd, Soy as a prevention strategy for Osteoporosis Posted in Bone Health , Bone Loss , Calcium , Nutrition , Prevention , Soy on Mar 30th, The lack of agreement in the literature is thought to be related to variations in study design […] Read Full Post ».

Vitamin D2 vs Vitamin D3; is one form better than the other? Most of our vitamin D comes […] Read Full Post ». Phytoestrogen Intake Prevents Bone Loss Posted in Bone Loss , Menopause , Phytoestrogen on Dec 11th, Bone density at the femoral neck and lumbar spine was tested after 24 months along with serum levels of bone-specific alkaline phosphatase, markers […] Read Full Post ».

Stop using maritime pine at least 2 weeks before a scheduled surgery. Moderate Be cautious with this combination. Medications for diabetes Antidiabetes drugs Maritime pine might lower blood sugar levels.

Taking maritime pine along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely. Medications that decrease the immune system Immunosuppressants Maritime pine can increase the activity of the immune system.

Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking maritime pine along with these medications might decrease the effects of these medications.

Taking maritime pine along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Herbs and supplements that might lower blood sugar Maritime pine might lower blood sugar.

Taking it with other supplements with similar effects might lower blood sugar too much. Examples of supplements with this effect include aloe, bitter melon, cassia cinnamon, chromium, and prickly pear cactus.

Herbs and supplements that might slow blood clotting Maritime pine might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people.

Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng. There are no known interactions with foods. Maritime pine bark extract has most often been used by adults at a dose of 50 mg, taken times daily, for up to one year. It's also used in various products, including creams and topical powders.

Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

Other names. Condensed Tannins, Écorce de Pin, Écorce de Pin Maritime, Extrait d'Écorce de Pin, French Marine Pine Bark Extract, French Maritime Pine Bark Extract, Leucoanthocyanidins, Maritime Bark Extract, Oligomères de Procyanidine, Oligomères Procyanidoliques, Oligomeric Proanthocyanidins, OPC, OPCs, PCO, PCOs, Pine Bark, Pine Bark Extract, Pinus pinaster, Pinus maritima, Proanthocyanidines Oligomériques, Procyanidin Oligomers, Procyanodolic Oligomers, Pycnogenol, Pycnogénol, Pygenol, Tannins Condensés.

Belcaro G, Cornelli U, Cesarone MR, et al. Preventive effects of Pycnogenol® on cardiovascular risk factors including endothelial function and microcirculation in subjects recovering from coronavirus disease COVID Minerva Med ; View abstract.

Cesarone MR, Hu S, Belcaro G, et al. Pycnogenol®-Centellicum® supplementation improves lung fibrosis and post-COVID lung healing. Malekahmadi M, Shadnoush M, Islam SMS, et al. The effect of French maritime pine bark extract supplementation on inflammation, nutritional and clinical status in critically ill patients with traumatic brain injury: A randomized controlled trial.

Phytother Res ; Cotellese R, Hu S, Cesarone MR, et al. Pycnogenol® supplementation prevents inflammation and symptoms in recurrent, non-severe urinary infections. Panminerva Med ; Ledda A, Hu S, Cesarone MR, et al.

Evid Based Complement Alternat Med ; Zhao H, Wu J, Wang N, Grether-Beck S, Krutmann J, Wei L. Oral pycnogenol intake benefits the skin in urban Chinese outdoor workers: a randomized, placebo-controlled, double-blind, and crossover intervention study. Skin Pharmacol Physiol ; Majidi Z, Ansari M, Maghbooli Z, et al.

Oligopin supplementation mitigates oxidative stress in postmenopausal women with osteopenia: a randomized, double-blind, placebo-controlled trial. Phytomedicine ; Lima PB, Dias JAF, Esposito ACC, Miot LDB, Miot HA.

French maritime pine bark extract pycnogenol in association with triple combination cream for the treatment of facial melasma in women: a double-blind, randomized, placebo-controlled trial. J Eur Acad Dermatol Venereol ; Navval-Esfahlan E, Rafraf M, Asghari S, Imani H, Asghari-Jafarabadi M, Karimi-Avval S.

Effect of French maritime pine bark extract supplementation on metabolic status and serum vascular cell adhesion molecule-1 levels in patients with type 2 diabetes and microalbuminuria. Complement Ther Med ; Manabe K, Kaidzu S, Tsutsui A, et al.

J Clin Biochem Nutr ; Aldret RL, Bellar D. A Double-Blind, Cross-Over Study to Examine the Effects of Maritime Pine Extract on Exercise Performance and Postexercise Inflammation, Oxidative Stress, Muscle Soreness, and Damage.

J Diet Suppl. Cesarone MR, Belcaro G, Agus GB, et al. Chronic venous insufficiency and venous microangiopathy: management with compression and Pycnogenol®. Minerva Cardioangiol. Hu S, Hosoi M, Belcaro G, et al.

Management of mild, primary Raynaud Syndrome: supplementation with Pycnogenol®. Cesarone MR, Belcaro G, Hosoi M, et al. Supplementary management with Pycnogenol® in Parkinson's disease to prevent cognitive impairment.

J Neurosurg Sci. Vinciguerra G, Belcaro G, Feragalli B, et al. PycnoRacer®, a fitness drink including Pycnogenol®, improves recovery and training in the Cooper test. Belcaro G, Cesarone MR, Cornelli U, et al. Xerostomia: prevention with Pycnogenol® supplementation: a pilot study. Minerva Stomatol.

Cesarone MR, Belcaro G, Scipione C, et al. Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox®. Minerva Ginecol. Pourmasoumi M, Hadi A, Mohammadi H, Rouhani MH. Effect of pycnogenol supplementation on blood pressure: A systematic review and meta-analysis of clinical trials.

Phytother Res. Fogacci F, Tocci G, Sahebkar A, Presta V, Banach M, Cicero AFG. Effect of Pycnogenol on Blood Pressure: Findings from a PRISMA Compliant Systematic Review and Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled, Clinical Studies.

Smetanka A, Stara V, Farsky I, Tonhajzerova I, Ondrejka I. Pycnogenol supplementation as an adjunct treatment for antidepressant-induced sexual dysfunction. Physiol Int. Luzzi R, Belcaro G, Hu S, et al. Efficacy of Pycnogenol supplementation in remission phases of Sjögren syndrome.

doi: Ledda A, Belcaro G, Feragalli B, et al. Benign prostatic hypertrophy: Pycnogenol supplementation improves prostate symptoms and residual bladder volume.

Minerva Med. Hu S, Belcaro G, Ledda A, et al. Behçet syndrome: effects of Pycnogenol supplementation during regression phases. Hadi A, Pourmasoumi M, Mohammadi H, Javaheri A, Rouhani MH.

The impact of pycnogenol supplementation on plasma lipids in humans: A systematic review and meta-analysis of clinical trials. Feragalli B, Dugall M, Luzzi R, et al. Pycnogenol: supplementary management of symptomatic osteoarthritis with a patch. An observational registry study. Minerva Endocrinol.

Belcaro G, Dugall M, Hu S, et al. Prevention of recurrent venous thrombosis and post-thrombotic syndrome. Belcaro G, Cornelli U, Dugall, M, Hosoi M, Cotllese R, Feragalli B.

Long-haul flights, edema, and thrombotic events: prevention with stockings and Pycnogenol supplementation LONFLIT Registry Study.

Minverva Cardioangiologica. Ezzikouri S, Nishimura T, Kohara M, et al. Inhibitor effects of Pycnogenol on hepatitis C virus replication. Antiviral Res. Belcaro G, Luzzi R, Hu S, et al. Improvement in signs and symptoms in psoriasis patients with Pycnogenol supplementation. Panminerva Med. Belcaro G, Gizzi G, Pellegrini L, et al.

Pycnogenol in postpartum symptomatic hemorrhoids. Belcaro G, Dugall M, Hosol M, et al. Pycnogenol and centella asiatica for asymptomatic atherosclerosis progression.

Int Angiol. Ikuyama S, Fan B, Gu J, Mukae K, Watanabe H. Molecular mechanism of intracellular lipid accumulation: suppressive effect of Pycnogenol in liver cells. Improvement in symptoms and cochlear flow with Pycnogenol in patients with Meniere's disease and tinnitus.

Belcaro G, Cesarone R, Steigerwalt J, et al. Jet-lag: prevention with Pycnogenol. Preliminary report: evaluation in healthy individuals and in hypertensive patients. Matsumori A, Higuchi H, Shimada M.

French maritime pine bark extract inhibits viral replication and prevents development of viral myocarditis. J Card Fail.

Belcaro G, Luzzi R, Dugall M, Ippolito E, Saggino A. Pycnogenol improves cognitive function, attention, mental performance and specific professional skills in healthy professionals aged Sarikaki V, Rallis M, Tanojo H, et al. In vitro percutaneous absorption of pine bark extract Pycnogenol in human skin.

J Toxicol ; Luzzi R, Belcaro G, Hosoi M, et al. Normalization of cardiovascular risk factors in pre-menopausal women with Pycnogenol. Valls RM, Llaurado E, Fernandez-Castillo S, et al.

Effects of low molecular weight procyanidin rich extract from French maritime bark on cardiovascular disease risk factors in stage-1 hypertensive subjects: randomized, double-blind, crossover, placebo-controlled intervention trial. Hosoi M, Belcaro G, Saggino A, Luzzi R, Dugall M, Feragalli B.

Pycnogenol supplementation in minimal cognitive dysfunction. J Nuerosurg Sci. Belcaro G, Dugall M, Ippolito E, Hus S, Saggino A, Feragalli B. The COFU3 Study. Improvement in cognitive function, attention, mental performance with Pycnogenol in healthy subjects with high oxidative stress.

J Neurosurg Sci Dec; Belcaro G, Dugall M. Preservation of muscular mass and strength in aged subjects with Pycnogenol supplementation. Minerva Ortopedica e Traumatologica Sept; Belcaro G, Dugall M, Luzzi R, Ippolito E, Cesarone MR. Postpartum varicose veins: supplementation with pycnogenol or elastic compression-A month follow-up.

Int J Angiol. Pycnogenol supplementation improves the control of irritable bowel syndrome symptoms. Belcaro G. A clinical comparison of pycnogenol, antistax, and stocking in chronic venous insufficiency.

Epub Jul Luzzi R, Belcaro G, Ippolito E. Carotid plaque stabilization induced by the supplement association Pycnogenol and centella asiatica Centellicum. Belcaro G, Dugall M, Ippolito E, et al.

Pycnogenol and centella asiatica to prevent asymptomatic atherosclerosis progression in clinical events. Taxon: Pinus pinaster Aiton. National Plant Germplasm System.

Accessed May 29, Vinciguerra G, Belcaro G, Bonanni E, et al. Evaluation of the effects of supplementation with Pycnogenol on fitness in normal subjects with the Army Physical Fitness Test and in performances of athletes in the minute triathlon.

J Sports Med Phys Fitness ; Sahebkar A. A systematic review and meta-analysis of the effects of pycnogenol on plasma lipids. J Cardiovasc Pharmacol Ther ; Khurana H, Pandey RK, Saksena AK, Kumar A. An evaluation of vitamin E and pycnogenol in children suffering from oral mucositis during cancer chemotherapy.

Oral Dis ; Bottari A, Belcaro G, Ledda A, et al. Lady Prelox improves sexual function in generally healthy women of reproductive age. Minerva Ginecol ; Belcaro G, Shu H, Luzzi R, et al. Improvement of common cold with Pycnogenol: a winter registry study.

Belcaro G, Dugall M, Luzzi R, Hosoi M, Corsi M. Improvements of venous tone with pycnogenol in chronic venous insufficiency: an ex vivo study on venous segments.

Int J Angiol ; Belcaro G, Cornelli U, Luzzi R, et al. Pycnogenol supplementation improves health risk factors in subjects with metabolic syndrome. Asmat U, Abad K, Ismail K. Diabetes mellitus and oxidative stress-a concise review. Saudi Pharma J Maritim AC, Sanders RA, Watkins JB 3rd.

Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol ; Farid R, Mirfeizi Z Mirheidari M Z Rezaieyazdi Mansouri H Esmaelli H. Pycnogenol® supplementation reduces pain and stiffness and improves physical function in adults with knee osteoarthritis.

Nutrition Research ; Roseff SJ, Gulati R. Improvement of sperm quality by pycnogenol. Eur Bull Drug Res ; Durackova, B. Trebatický V. Novotný I. Žit®anová J. Lipid metabolism and erectile function improvement by Pycnogenol®, extract from the bark of Pinus pinaster in patients suffering from erectile dysfunction - a pilot study.

Hosseini S, Pishnamazi S Sadrzadeh SMH Farid F Farid R Watson RR. Pycnogenol in the management of asthma. J Medicinal Food ; Durackova, Z. Lipid metabolism and erectile dysfunction improvement by Pycnogenol R , extract from the bark of Pinus pinaster in patients suffering from erectile dysfunction -- a pilot study.

Kohama T, Negami M. Effect of Low-dose French Maritime Pine Bark Extract on Climacteric Syndrome in Perimenopausal Women: A Randomized, Double-blind, Placebo-controlled Trial. J Reproductive Med ; Schmidtke I, Schoop W. Pycnogenol: stasis oedema and its medical treatment.

Schweizerische Zeitschrift fur GanzheitsMedizin ; Hosseini, S. A randomized, double blind, placebo controlled, prospective 16 week crossover study to determine the role of Pycnogenol R in modifying blood pressure in mildly hypertensive patients. Wang S, Tan D Zhao Y et al. The effect of pycnogenol on the microcirculation, platelet function and ischemic myocardium in patients with coronary artery diseases.

Wei, Z. Pycnogenol enhances endothelial cell antioxidant defenses. Redox Report ; Virgili, F. Procyanidins extracted from Pinus maritima Pycnogenol : scavengers of free radical species and modulators of nitrogen monoxide metabolism in activated murine RAW Free Radic. Biol Med ;24 Macrides, T.

A comparison of the hydroxyl radical scavenging properties of the shark bile steroid 5 beta-scymnol and plant pycnogenols. Biochem Mol Biol Int ; Noda, Y. Hydroxyl and superoxide anion radical scavenging activities of natural source antioxidants using the computerized JES-FR30 ESR spectrometer system.

Furumura, M. Oral administration of French maritime pine bark extract Flavangenol R improves clinical symptoms in photoaged facial skin. Aging ; Perera, N. Phlebotonics for haemorrhoids. Schoonees, A. Pycnogenol R extract of French maritime pine bark for the treatment of chronic disorders.

Pycnogenol R for the treatment of chronic disorders. Marini, A. Pycnogenol R effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women.

Skin Pharmacol. Physiol ; Mach, J. Enseleit, F. Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study. Heart J. Luzzi, R. Pycnogenol R supplementation improves cognitive function, attention and mental performance in students.

Errichi, S. Supplementation with Pycnogenol R improves signs and symptoms of menopausal transition. Belcaro, G. Pycnogenol R improvements in asthma management. Errichi, B. Prevention of post thrombotic syndrome with Pycnogenol R in a twelve month study. Aoki, H. Clinical assessment of a supplement of Pycnogenol R and L-arginine in Japanese patients with mild to moderate erectile dysfunction.

Ohkita, M. Pharmacology in health foods: improvement of vascular endothelial function by French maritime pine bark extract Flavangenol.

Dvorakova, M. How does pycnogenol R influence oxidative damage to DNA and its repair ability in elderly people? Henrotin, Y. Nutraceuticals: do they represent a new era in the management of osteoarthritis? Pavone, C. Safety and efficacy in the treatment of lower urinary tract symptoms.

Prospective study on patients]. Drieling, R. No beneficial effects of pine bark extract on cardiovascular disease risk factors. Reuter, J. Which plant for which skin disease?

Part 2: Dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. Grossi, M. Improvement in cochlear flow with Pycnogenol R in patients with tinnitus: a pilot evaluation.

Stuard, S. Kidney function in metabolic syndrome may be improved with Pycnogenol R. Cesarone, M. Improvement of signs and symptoms of chronic venous insufficiency and microangiopathy with Pycnogenol: a prospective, controlled study. Kidney flow and function in hypertension: protective effects of pycnogenol in hypertensive participants--a controlled study.

Pycnogenol treatment of acute hemorrhoidal episodes. Steigerwalt, R. Pycnogenol improves microcirculation, retinal edema, and visual acuity in early diabetic retinopathy.

Daily consumption of Reliv Glucaffect for 8 weeks significantly lowered blood glucose and body weight in 50 subjects. Rucklidge, J. Nutrient supplementation approaches in the treatment of ADHD.

Zibadi, S. Reduction of cardiovascular risk factors in subjects with type 2 diabetes by Pycnogenol supplementation. Variations in C-reactive protein, plasma free radicals and fibrinogen values in patients with osteoarthritis treated with Pycnogenol.

Ryan, J. An examination of the effects of the antioxidant Pycnogenol on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population. J Psychopharmacol.

Cisar, P. Effect of pine bark extract Pycnogenol on symptoms of knee osteoarthritis. Suzuki, N. French maritime pine bark extract significantly lowers the requirement for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study.

J Reprod. Treatment of osteoarthritis with Pycnogenol. The SVOS San Valentino Osteo-arthrosis Study. Evaluation of signs, symptoms, physical performance and vascular aspects. Urinary catecholamines in children with attention deficit hyperactivity disorder ADHD : modulation by a polyphenolic extract from pine bark pycnogenol.

Nikolova, V. Sofiia ; Angiology ; Chovanova, Z. Res ; The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder ADHD.

Voss, P. Ferritin oxidation and proteasomal degradation: protection by antioxidants. Diabetic ulcers: microcirculatory improvement and faster healing with pycnogenol. Ahn, J. Effects of plant extracts on microbial growth, color change, and lipid oxidation in cooked beef.

Food Microbiol. Grimm, T. Single and multiple dose pharmacokinetics of maritime pine bark extract pycnogenol after oral administration to healthy volunteers. Clin Pharmacol ; Comparison of Pycnogenol and Daflon in treating chronic venous insufficiency: a prospective, controlled study.

Clin Appl Thromb. Trebaticka, J. Treatment of ADHD with French maritime pine bark extract, Pycnogenol. Child Adolesc.

DEAR Muscular strength and balance CLINIC: My Organic holistic wellness had osteoporosis ostekporosis suffered a devastating fall in prevenrion early 60s that Green tea extract benefits never recovered from. I am 42, and Preventiin want to be proactive about my bone health. What screening do I need, and what if any supplements are necessary to optimize my bone health? What factors can help me maintain strong bones as I age? ANSWER: Osteoporosis is a condition that causes the bones to thin and lose their strength. When bones become weaker, sudden fractures soteoporosis occur, even with minimal trauma. And although this merely reflects the Pycnogenol and osteoporosis prevention course of life, we still want to Pycnkgenol Muscular strength and balance to Pycnogenoll fullest. We prevenhion a fresh new Nutritional benefits of organic foods of the Osteoporksis and embrace ageing as happily as prevenfion. The Pycnogfnol Health Organization has declared the years between and to be the United Nations Decade of Healthy Ageing. There are more than one billion people worldwide who are older than 60 and, with life expectancies rising, more and more efforts are needed to ensure that the ageing process is a happy and healthy one. Evidence of the beneficial impact of Pycnogenol ® French maritime pine bark extract in the elderly is supported by a significant number of scientific publications.