Alternate-day fasting and anti-aging effects -
View in Article Scopus 10 PubMed Crossref Google Scholar. Protein Homeostasis and Aging: Taking Care of Proteins From the Cradle to the Grave. View in Article Scopus Crossref Google Scholar.
Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization. View in Article Scopus 37 Crossref Google Scholar. New Insights into the Role of Mitochondrial Dynamics and Autophagy during Oxidative Stress and Aging in the Heart.
Cardioprotection and lifespan extension by the natural polyamine spermidine. View in Article Scopus 92 PubMed Abstract Full Text Full Text PDF Google Scholar. Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury.
AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control. Fine-tuning of AMPK—ULK1—mTORC1 regulatory triangle is crucial for autophagy oscillation. View in Article Scopus 30 PubMed Crossref Google Scholar.
View in Article Scopus 16 Crossref Google Scholar. View in Article Scopus 86 Crossref Google Scholar. View in Article Scopus 13 PubMed Abstract Full Text Full Text PDF Google Scholar. The influence of fasting and energy restricting diets on IGF-1 levels in humans: A systematic review and meta-analysis.
View in Article Scopus 51 PubMed Crossref Google Scholar. Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
View in Article Scopus 23 PubMed Crossref Google Scholar. Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia.
Lysosomes Mediate Benefits of Intermittent Fasting in Cardiometabolic Disease: The Janitor Is the Undercover Boss. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.
Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential. View in Article Scopus 95 PubMed Crossref Google Scholar.
Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism. AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction.
Chronic akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy. The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis.
Akt2 ablation prolongs life span and improves myocardial contractile function with adaptive cardiac remodeling: role of Sirt1-mediated autophagy regulation. View in Article Scopus 88 PubMed Crossref Google Scholar.
Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways. Alternate-day fasting protects the rat heart against age-induced inflammation and fibrosis by inhibiting oxidative damage and NF-kB activation. View in Article Scopus 80 PubMed Crossref Google Scholar.
A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice. View in Article Scopus 43 PubMed Crossref Google Scholar. Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart.
Long-Term Caloric Restriction Ameliorates the Decline in Diastolic Function in Humans. Opposing effects on cardiac function by calorie restriction in different-aged mice. View in Article Scopus 39 PubMed Crossref Google Scholar.
Effects of calorie restriction on cardioprotection and cardiovascular health. View in Article Scopus 69 PubMed Abstract Full Text Full Text PDF Google Scholar. Impact of long-term caloric restriction on cardiac senescence: Caloric restriction ameliorates cardiac diastolic dysfunction associated with aging.
View in Article Scopus 19 Crossref Google Scholar. Intermittent Fasting Results in Tissue-Specific Changes in Bioenergetics and Redox State. View in Article Scopus 55 PubMed Crossref Google Scholar. Late-onset dietary restriction compensates for age-related increase in oxidative stress and alterations of HSP 70 and synapsin1 protein levels in male Wistar rats.
View in Article Scopus 27 PubMed Crossref Google Scholar. Impact of Dietary Restriction Regimens on Mitochondria, Heart, and Endothelial Function: A Brief Overview. View in Article Scopus 13 PubMed Crossref Google Scholar.
View in Article Scopus 74 PubMed Abstract Full Text Full Text PDF Google Scholar. Time-restricted feeding attenuates age-related cardiac decline in Drosophila. Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease.
Effects of Ramadan fasting on cardiovascular risk factors: a prospective observational study. Comparison of effects of diet versus exercise weight loss regimens on LDL and HDL particle size in obese adults. View in Article Scopus 81 PubMed Crossref Google Scholar.
Intermittent Fasting Inhibits High-Fat Diet-Induced Atherosclerosis by Ameliorating Hypercholesterolemia and Reducing Monocyte Chemoattraction. Time-Restricted Feeding Enhances Early Atherosclerosis in Hypercholesterolemic Mice. View in Article Scopus 5 PubMed Crossref Google Scholar.
Effect of hypoxia-inducible factor-1α gene therapy on walking performance in patients with intermittent claudication. Use of a Constitutively Active Hypoxia-Inducible Factor-1α Transgene as a Therapeutic Strategy in No-Option Critical Limb Ischemia Patients.
View in Article Scopus 31 PubMed Crossref Google Scholar. Long-term intermittent fasting improves neurological function by promoting angiogenesis after cerebral ischemia via growth differentiation factor 11 signaling activation.
Dietary Intake Regulates White Adipose Tissues Angiogenesis via Liver Fibroblast Growth Factor 21 in Male Mice. View in Article Scopus 12 PubMed Crossref Google Scholar.
Prolonged Fasting Improves Endothelial Progenitor Cell-Mediated Ischemic Angiogenesis in Mice. View in Article Scopus 19 PubMed Crossref Google Scholar. Intermittent Food Deprivation Improves Cardiovascular and Neuroendocrine Responses to Stress in Rats. Assessment of enhanced endothelium-dependent vasodilation by intermittent fasting in Wistar albino rats.
Effects and possible mechanisms of intermittent fasting on health and disease: a narrative review. View in Article Scopus 3 PubMed Crossref Google Scholar. Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability.
A rapid switch in sympathetic neurotransmitter release properties mediated by the p75 receptor. Chronic Alternate Day Fasting Results in Reduced Diastolic Compliance and Diminished Systolic Reserve in Rats.
Doxorubicin Exposure Causes Subacute Cardiac Atrophy Dependent on the Striated Muscle—Specific Ubiquitin Ligase MuRF1. View in Article Scopus 74 PubMed Crossref Google Scholar. Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway.
View in Article Scopus 21 PubMed Crossref Google Scholar. The interplay between autophagy and mitochondrial dysfunction in oxidative stress-induced cardiac aging and pathology. View in Article Scopus 77 PubMed Abstract Full Text Full Text PDF Google Scholar.
Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo.
View in Article Scopus 76 PubMed Crossref Google Scholar. Influence of long-term caloric restriction on myocardial and cardiomyocyte contractile function and autophagy in mice. Autophagy Is Pro-Senescence When Seen in Close-Up, but Anti-Senescence in Long-Shot.
View in Article Scopus 85 PubMed Crossref Google Scholar. Type 2 Diabetes Inhibited Human Mesenchymal Stem Cells Angiogenic Response by Over-Activity of the Autophagic Pathway. View in Article Scopus 46 PubMed Crossref Google Scholar. The Beneficial and Adverse Effects of Autophagic Response to Caloric Restriction and Fasting.
Time-Restricted Eating in Metabolic Syndrome—Focus on Blood Pressure Outcomes. View in Article Scopus 1 PubMed Crossref Google Scholar. Relation between nocturnal decline in blood pressure and mortality. The Ohasama Study. Heterogeneity of prognostic studies of hour blood pressure variability: systematic review and meta-analysis.
View in Article Scopus 41 Crossref Google Scholar. Night—day blood pressure ratio and dipping pattern as predictors of death and cardiovascular events in hypertension.
View in Article Scopus 18 PubMed Crossref Google Scholar. Impact of Blood Pressure Variability on Cardiovascular Events in Elderly Patients with Hypertension. The effect of ramadan fasting and physical activity on body composition, serum osmolarity levels and some parameters of electrolytes in females.
View in Article Scopus 36 PubMed Crossref Google Scholar. Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome. Meal timing during alternate day fasting: Impact on body weight and cardiovascular disease risk in obese adults.
Effect of intensive dietetic interventions on weight and glycaemic control in overweight men with Type II diabetes: a randomised trial. Effect of a Six-Week Intermittent Fasting Intervention Program on the Composition of the Human Body in Women over 60 Years of Age. View in Article Scopus 40 PubMed Crossref Google Scholar.
Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism1,2.
Comparison of various surrogate obesity indicators as predictors of cardiovascular mortality in four European populations. Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality: sixteen years of follow-up in US women.
Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity. Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes.
The effects of modified alternate-day fasting diet on weight loss and CAD risk factors in overweight and obese women.
Intermittent fasting modulation of the diabetic syndrome in streptozotocin-injected rats. View in Article Scopus 37 PubMed Crossref Google Scholar. Effects of modified alternate-day fasting regimens on adipocyte size, triglyceride metabolism, and plasma adiponectin levels in mice.
View in Article Scopus 67 PubMed Abstract Full Text Full Text PDF Google Scholar. Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats. View in Article Scopus 77 PubMed Crossref Google Scholar.
A randomized pilot study comparing zero-calorie alternate-day fasting to daily caloric restriction in adults with obesity.
Intermittent fasting combined with calorie restriction is effective for weight loss and cardio-protection in obese women. Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trial. Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects.
View in Article Scopus 3 PubMed Abstract Full Text Full Text PDF Google Scholar. Time-Restricted Eating to Reduce Cardiovascular Risk Among Older Breast Cancer Survivors: A Single-Arm Feasibility Study.
Metabolic therapy for managing heart failure with preserved ejection fraction. Association of periodic fasting lifestyles with survival and incident major adverse cardiovascular events in patients undergoing cardiac catheterization.
Acute heart failure presentations and outcomes during the fasting month of Ramadan: an observational report from seven Middle Eastern countries. Clinical outcomes of fasting in patients with chronic heart failure with preserved ejection fraction: A prospective analysis.
Time of Eating and Mortality in U. Adults with Heart Failure: Analyses of the National Health and Nutrition Examination Survey Fasting supercharges metabolism, making the body more efficient at breaking down nutrients and burning calories.
It also slows down the degradation of DNA, which is what occurs when we age, and accelerates DNA repair, thus slowing down the aging process. Additionally, fasting can reduce the chronic inflammation that occurs as people age. Fasting has been shown to improve cholesterol levels by increasing high-density lipoprotein HDL , or good cholesterol, and decreasing low-density lipoprotein LDL , or bad cholesterol.
It can also lower blood pressure, improve glucose control, and reduce fat deposits in the liver. It can also help with sleep quality, cognition and memory. This starts with protein. Ideally, some form of protein should be consumed during every meal or snack.
These protein sources could include eggs, Greek yogurt, protein shakes, chicken, fish, beef or plant-based proteins, such as beans and lentils. The body also needs a good balance of other nutrients, including fruits and vegetables and healthy carbohydrate sources, such as brown rice, whole wheat bread and quinoa.
Intermittent fasting works best for people in two main groups, including those who:. Conversely, these four groups of people would not benefit from intermittent fasting:. An exercise regimen will increase the benefits of intermittent fasting.
It can be a beneficial program for a lot of people. Mayo Clinic Sports Medicine in Minneapolis and Rochester offer a premier continuum of care that ranges from prevention and treatment to rehabilitation and performance enhancement whether you are a top athlete or an active individual.
Mayo Clinic is a nonprofit organization committed to clinical practice, education and research, providing expert, comprehensive care to everyone who needs healing. The Business Journals.
Select a City. Louis Tampa Bay Washington, D. Paul Business Journal. By Laurie Garrison — Contributor. Feb 28, Whole day — fasting on some days, eating regularly on others.
Age associated neurodegenerative changes are acknowledged antti-aging play anc causative role in a Alternate-day fasting and anti-aging effects of neurological diseases that accompany anti-afing in organisms. To alleviate the deteriorative effects fastint aging in faeting brain, we Lice treatment for long hair the effects oftwo types of intermittent fastint IF methods: alternate day Alterbate-day Alternate-day fasting and anti-aging effects and time- restricted feeding TRF in young 3 months and old 24 months in male Wistar rats comparing the results with age matched controls. The evaluation of biomarkers of oxidative stress showed significant decline in the old ADF and TRF groups in addition to up regulation in antioxidant levels. It was observed that ADF and TRF methods helped reduce ROS accumulation in the mitochondria and increased the activity of the electron transport chain complexes especially C-I and III. Gene expression analysis of autophagy genes like beclin and LC3B showed upregulated expression in ADF and TRF group. Intermittent fasting effectss an eating strategy that gained Alternate-day fasting and anti-aging effects as a weight loss technique about 10 years ago. In addition Plant-based sports supplements reported Fatsing loss benefits, research has shown intermittent fasting has an anti--aging effect and fastiing improve markers of physical and mental health, according to Luke Coreya registered dietitian with Mayo Clinic Sports Medicine and sports nutritionist with the Minnesota Timberwolves. Outside of that window, you eat very little or no food at all. During a fasting period, the body uses its own fat stores as an energy source. The last meal of the day provides enough energy to fuel the body for a couple of hours.
Siehe bei mir!