L-carnitine and antioxidant activity -
There was a gradual increase in plasma concentrations of superoxide dismutase SOD , glutathione peroxidase GSH-Px , catalase and total antioxidative capacity T-AOC in the first 3. The plasma concentrations of SOD, GSH-Px, catalase and T-AOC returned to baseline levels within 24 h. In conclusion, L-carnitine increases activities of antioxidant enzymes and the total antioxidant capacity in healthy subjects.
It may be useful as a supplementary therapy for chronic illnesses involving excessive oxidative stress. Already have an account? Sign in here. The Tohoku Journal of Experimental Medicine. Online ISSN : Print ISSN : ISSN-L : Journal home Advance online publication All issues Featured articles About the journal.
Single Dose Administration of L-Carnitine Improves Antioxidant Activities in Healthy Subjects. Yu Cao , Hai-jun Qu , Ping Li , Chun-bo Wang , Le-xin Wang , Zhi-wu Han Author information.
Yu Cao Department of Pharmacy, the Affiliated Hospital of Medical College, Qingdao University Hai-jun Qu Department of Pharmacy, the Affiliated Hospital of Medical College, Qingdao University Ping Li Department of Pharmacy, the Affiliated Hospital of Medical College, Qingdao University Chun-bo Wang Department of Pharmacology, Medical College, Qingdao University Le-xin Wang School of Biomedical Sciences, Charles Sturt University Zhi-wu Han Department of Pharmacy, the Affiliated Hospital of Medical College, Qingdao University Author contributions.
Corresponding author. Keywords: catalase , glutathione peroxidase , L-carnitine , superoxide dismutase , total antioxidative capacity. JOURNAL FREE ACCESS. Published: Received: May 06, Available on J-STAGE: June 23, Accepted: June 06, Advance online publication: - Revised: -.
Download PDF K Download citation RIS compatible with EndNote, Reference Manager, ProCite, RefWorks. Article overview. References Related articles 0. Figures 0. L-carnitine plays an important regulatory role in the mitochondrial transport of long-chain free fatty acids.
In this study, the antioxidant activity of L-carnitine was investigated as in vitro. The antioxidant properties of the L-carnitine were evaluated by using different antioxidant assays such as 1, 1-diphenylpicryl-hydrazyl free radical DPPH. scavenging, total antioxidant activity, reducing power, superoxide anion radical scavenging, hydrogen peroxide scavenging and metal chelating activities.
Total antioxidant activity was measured according to ferric thiocyanate method.
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