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Data presented last week at the European Association for the Study of Diabetes annual meeting in Hamburg, Germany, offered some reassurance. Researchers, including some from Eli Lilly, used magnetic resonance imaging to evaluate changes in body composition seen in people taking tirzepatide and concluded that some of the muscle volume lost was actually intramuscular fat.

Specialists say that both gastrointestinal adverse events and muscle-mass loss can be prevented or managed with adequate dietary modifications, physical activity and other drugs.

Drucker notes that GLP-1 drugs have mainly been studied in people with type 2 diabetes or obesity. But, for most people with obesity, the benefits far exceed the risks, Almandoz notes.

This article is reproduced with permission and was first published on October 13, October 19, 4 min read. Recent studies evaluate risks associated with drugs such as Wegovy and Mounjaro. Gastrointestinal problems The latest generation of anti-obesity drugs mimic a hormone called glucagon-like peptide 1 GLP-1 , which is associated with appetite regulation.

I have to take care of my kid," she said. It's just not an option. The vast majority of health plans — especially those that serve older adults and low-income families — do not cover weight loss drugs. And fewer than 20 Medicaid programs nationwide pay for them, according to a report from the Urban Institute , a nonprofit research organization.

AHIP, a group that represents the insurance industry, maintains that there is not yet enough evidence to show the drugs are effective options for long-term weight loss.

Noel Bairey Merz, scientific adviser to the Women's Heart Alliance and director of the Barbra Streisand Women's Heart Center at Cedars-Sinai Heart Institute in Los Angeles, said that the drugs' effect on weight loss may not reflect their true health benefits.

They were developed as type 2 diabetes drugs. As such, the medications "clearly have a cardiovascular benefit," regardless of a person's weight loss, she said.

To be clear, semaglutide is not the answer for everyone with obesity. It can cause serious side effects, such as vomiting and nausea. As with treating other diseases, different types of therapy may be necessary. Still, the massive gap in insurance coverage for weight loss medications is rooted in weight discrimination, said James Zervios, vice president and chief of staff for the Obesity Action Coalition.

Most patients who seek a doctor's help for their weight are often simply advised to "try to eat less and move more" or to start a food diary, he said. Erika Edwards is a health and medical news writer and reporter for NBC News and "TODAY.

IE 11 is not supported. For an optimal experience visit our site on another browser. SKIP TO CONTENT. NBC News Logo. Kansas City shooting Politics U. My News Manage Profile Email Preferences Sign Out. Wegovy is a weekly injection approved by the U. Food and Drug Administration FDA in for long-term weight management.

It's the first drug approved for this purpose since Both Wegovy and Ozempic include the same active ingredient semaglutide. However, Ozempic has lower doses of semaglutide and was developed for people with type 2 diabetes.

Wegovy contains higher doses of semaglutide and was formatted to help with weight loss. It's become a popular trend: taking Ozempic for weight loss. It's a once-weekly injection that was approved by the FDA for use in adults with type 2 diabetes.

Ozempic is not approved for weight loss. However, semaglutide is approved for weight loss under the brand name Wegovy.

Ozempic can help people lose weight. However, experts recommend that people avoid using Ozempic for weight loss since it's meant for people with type 2 diabetes.

Talk to your doctor about starting Wegovy instead if you're looking to lose weight. Read more about Ozempic for weight loss: Does it work, and what do experts recommend?

from UC Davis Health. There are no approved generic versions of either of these drugs, according to the FDA. Off-brand versions of these drugs have been seen at compounding pharmacies across the U.

People have reported adverse events to the FDA after using "generic" versions of semaglutide. Since people started off-label use of Ozempic for weight loss, type 2 diabetes patients who rely on the medication have struggled to find it.

Both Ozempic and Wegovy were listed on the FDA Drug Shortage List , as of September Like Ozempic , Mounjaro tirzepatide is another popular medication that has been used off label to help with weight loss.

Obesity Top fat burners a medical condition that can lead to other health problems. Weiggt the U. Obesity Deight calculated through body mass index BMI. This measures a person's height in relation to their weight. A BMI of is considered overweight. A BMI of more than 30 is categorized as obesity. Use this calculator to learn your BMI. We include products weihht think looss Popular weight loss pills for our readers. If lods buy through links on this page, we may earn Best forms of magnesium supplements small Poppular. Healthline only shows you brands Popular weight loss pills products pipls we stand behind. Prescription weight loss medications, Popular weight loss pills GLP-1 agonists, orlistat, and setmelanotide, may be effective for some people. But other lifestyle changes are still necessary for long-term success. When paired with other lifestyle changes and taken under the supervision of a healthcare professional, these drugs may offer an effective way to lower your weight. We reviewed all of the weight loss medications that are currently available, including how they work, who they might be appropriate for, research on their effectiveness, and potential safety concerns.