Curcumin for Immune Support -
Turmeric has long been used to support immunity. Karen Evennett examines the evidence. The magic immune-boosting ingredient is curcumin — the compound that gives turmeric its yellow pigment.
Curcumin is a polyphenol with anti-inflammatory properties and the ability to boost the amount of antioxidants your cells can make. Research now suggests that all the anti-inflammatory benefits we credit to turmeric may in fact be due to curcumin's ability to modulate the immune system.
As nutritional therapist Judy Watson from judywatsonnutritionist. uk explains, "Studies show it's a potent immunomodulatory agent that can modulate the activation of T cells, B cells, macrophages, neutrophils, natural killer cells, and dendritic cells.
And, combined with piperine black pepper in a supplement, it has significantly reduced weakness in patients with COVID Further supporting its usefulness to the immune system is the fact that curcumin has been found to block Epstein-Barr virus EBV , says Watson.
However, separate studies this year and last year suggest that inflammation caused by COVID may reactivate EBV in some people.
But, for its medicinal properties, you would have to take a supplement. Black pepper helps the absorption of curcumin, so that makes it all the more effective. It's important to cut out processed foods and especially ultra-processed foods. Replace these with a broad and varied range of plant-based foods," Watson says.
T cells protect us from pathogens such as bacteria, viruses and fungi and can also wipe out infected or cancerous cells. They also help B lymphocytes B cells to create antibodies that bind to pathogens and toxins and neutralise them so they can't enter a normal cell and cause infection.
These are your immune system's peacekeepers. They control or suppress other cells in the immune system, and are designed to send a signal to immunity to withdraw, pause an attack and stand down. Without their regulation and molecules, the immune system can get out of control, attacking your body inappropriately.
For optimal health you need sufficient but not excessive regulation by TREGS. Your system is effectively walking a tightrope to maintain just the right balance: insufficient immunity too many TREGS may increase incidence of infections and cancer, while an over-enthusiastic immune system too few TREGS may lead to damage to your own organs.
Macrophages act like proactive mops in the immune system — they're white blood cells that surround and kill microorganisms, remove dead cells, and stimulate the action of other immune system cells. Natural killer cells are killing machines that recognise changes in your own cells, killing them when they become infected with a virus.
Dotted around your body, but also making up 10 per cent of your white blood cells, they patrol and inspect each cell, responding to newly-formed tumours and any abnormal growth. These are a special type of immune cell found in tissues, such as the skin, that boost the response of other immune system cells.
Even in adulthood, brain neurons are capable of forming new connections, and in certain areas of the brain, they can multiply and increase in number. One of the main drivers of this process is brain-derived neurotrophic factor BDNF , which plays a role in memory and learning, and it can be found in areas of the brain responsible for eating, drinking, and body weight.
Both animal and human studies have found that curcumin may increase brain levels of BDNF. By doing this, it may be effective in delaying or even reversing many brain diseases and age-related decreases in brain function.
It may also help improve memory and attention , which seems logical given its effects on BDNF levels. However, more studies are needed to confirm this. Heart disease is the number one cause of death in the world. Research suggests that curcumin may help protect against many steps in the heart disease process.
Specifically, it helps improve the function of the endothelium or the lining of your blood vessels. Endothelial dysfunction is a major driver of heart disease. This is when your endothelium is unable to regulate blood pressure, blood clotting, and various other factors.
Several other studies also suggest that curcumin can lead to improvements in heart health. In addition, curcumin can help reduce inflammation and oxidation as discussed above , which can play a role in heart disease.
Many different forms of cancer appear to be affected by curcumin supplements. In fact, curcumin has been studied as a beneficial herb in cancer treatment and has been found to affect cancer growth and development.
Studies have shown that it can:. There is also evidence that curcumin may prevent cancer from occurring in the first place, especially cancers of the digestive system like colorectal cancer. In addition, research suggests that curcumin can help clear the buildup of protein tangles called amyloid plaques that are caused by the disease.
There are several different types of arthritis , most of which involve inflammation in the joints. In a study on people with osteoarthritis, curcumin appeared to be more effective in relieving pain than a placebo, and research has also found its effect to be similar to that of non-steroidal anti-inflammatory drugs NSAIDs.
In another study on rheumatoid arthritis, curcumin appeared to have helped reduce disease-related inflammation. That said, more study is needed to understand if curcumin can actually replace such drugs as a treatment for arthritis inflammation pain.
Curcumin has shown some promise in treating mood disorders. Its positive effects on the brain include boosting the brain neurotransmitters serotonin and dopamine, reducing inflammation, and encouraging brain plasticity. This suggests the herb may be an effective antidepressant.
Depression is also linked to reduced levels of BDNF and a shrinking hippocampus, a brain area with a role in learning and memory. Curcumin can help boost BDNF levels , potentially reversing some of these changes.
A animal study also found that curcumin may help reduce anxiety, though studies on humans are needed to verify this. Given that oxidation and inflammation are believed to play a role in aging, curcumin may have effects that go way beyond just preventing disease.
If you stick to 12 g or less , you are not likely to experience side effects such as diarrhea, constipation, or vomiting. Learn more about turmeric dosage.
People who are pregnant or nursing, people who have gallbladder or kidney problems, those with bleeding disorders, diabetes, or iron deficiency should limit turmeric. If you have any of these conditions, ask your doctor before taking turmeric. There is research suggesting that curcumin, the main component of turmeric, might help with reducing belly fat.
Learn more: Does turmeric help you lose weight? It may also help improve symptoms of depression and arthritis. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.
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Nutrition Evidence Based 10 Health Benefits of Tumeric and Curcumin. Medically reviewed by Imashi Fernando, MS, RDN, CDCES — By Kris Gunnars, BSc — Updated on November 27, What it is Medicinal properties Anti-inflammatory Antioxidants Brain health Heart disease Cancer Alzheimer's disease Arthritis Depression Aging FAQs Bottom line Many high-quality studies show that turmeric has major benefits for your body and brain.
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AVOID Taking Your TURMERIC This Way...3 Best Ways to Heal Your Body! Dr. Mandell Many high-quality studies show that turmeric has major benefits for Immund body Supplrt brain. Many Rehydration for improved mood Curcumin for Immune Support benefits come from its main active ingredient, curcumin. The spice known as turmeric could be one of the most effective nutritional supplements in existence. Turmeric is the spice that gives curry its yellow color. It has been used in India for thousands of years as both a spice and medicinal herb.
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