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What Michael Pollan Learned from Quitting Caffeine for 3 Months Gs is Probiotics for bone health Vegan-friendly Thai food used medicinally by Amazonian tribes for vz. A mature guarana fruit cs about the size of a coffee berry. It resembles the human cotfee, with a red shell encasing a black seed covered by a white aril. Guarana extract is made by processing the seeds into a powder 1. Amazonian tribes have used guarana for centuries for its therapeutic properties 2. It contains an impressive range of stimulants, such as caffeine, theophylline and theobromine. Guarana also boasts antioxidants, such as tannins, saponins and catechins 3.