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Understanding anti-depressant side effects

Understanding anti-depressant side effects

Media Understanding anti-depressant side effects. Understanxing, variants in genes such as CYP2C19 and CYP3A4 have effrcts linked to citalopram 25 and sertraline 26 differential metabolism and clearance. Supplementary Information - Supplementary figures. NaSSAs can also cause drowsiness and weight gain.

Understanding anti-depressant side effects -

Many other drugs are also metabolized by this same system. Depending on the interaction, there may be a higher or lower blood level of the two drugs. Sometimes only a dose adjustment is necessary, or it may be best to avoid one of the two drugs. If an SSRI is taken along with another drug that enhances serotonin activity, a rare condition called the serotonin syndrome may develop — racing heart, sweating, high fever, high blood pressure, and sometimes delirium.

In particular, SSRIs should not be mixed with certain other medications, especially the herbal remedy St. John's wort, monoamine oxidase inhibitors such as phenelzine Nardil , and clomipramine Anafranil.

The serotonin syndrome has also been reported when an SSRI is combined with lithium, the standard treatment for bipolar disorder. SSRIs are safer than tricyclic antidepressants for older people because they do not disturb heart rhythms and rarely cause dizziness that results in falls.

But liver function is less efficient in older people, so there is a greater risk of drug interactions involving the cytochrome P system. For that reason, older people do best with rapidly metabolized drugs like sertraline.

Any antidepressant may lose its effect after months or years, sometimes because the brain has become less responsive to the drug tolerance. Solutions include increasing the dose and switching to another antidepressant with a different mechanism of action.

Symptoms that may occur on suddenly stopping an SSRI include dizziness, loss of coordination, fatigue, tingling, burning, blurred vision, insomnia, and vivid dreams.

Less often, there may be nausea or diarrhea, flu-like symptoms, irritability, anxiety, and crying spells. The syndrome is usually mild but can be severe. Although none of these types of antidepressants should be stopped abruptly, paroxetine tends to produce the most intense discontinuation symptoms.

Here is a place where the longer-lasting drugs have an advantage; some clinicians switch to fluoxetine before gradually lowering the dose.

Potential risks to the fetus such as premature delivery and lower birth weight must be weighed against the considerable risks of untreated depression to both mother and child. More seriously depressed women are more likely to need antidepressant drugs while pregnant.

Similar cautions apply to nursing mothers. Although antidepressants may not cure depression, they can reduce symptoms. The first antidepressant you try may work fine. But if it doesn't relieve your symptoms or it causes side effects that bother you, you may need to try another.

So don't give up. Many kinds of antidepressants are available, and chances are you'll be able to find one that works well for you. And sometimes a combination of medicines may be an option. There are many types of antidepressants available that work in slightly different ways and have different side effects.

When choosing an antidepressant that's likely to work well for you, your health care provider may consider:. Many mental health experts believe that certain brain chemicals called neurotransmitters are associated with depression — particularly serotonin ser-o-TOE-nin , norepinephrine nor-ep-ih-NEF-rin and dopamine DOE-puh-meen.

Most antidepressants help relieve depression by affecting these neurotransmitters, sometimes called chemical messengers, which aid in communication between brain cells. Each type of antidepressant affects these neurotransmitters in slightly different ways.

Most antidepressants are generally safe, but the U. Food and Drug Administration FDA requires that all antidepressants carry black box warnings, the strictest warnings for prescriptions.

In some cases, children, teenagers and young adults under 25 may have an increase in suicidal thoughts or behavior when taking antidepressants, especially in the first few weeks after starting or when the dose is changed.

Anyone taking an antidepressant should be watched closely for worsening depression or unusual behavior. If you or someone you know has suicidal thoughts when taking an antidepressant, immediately contact your health care provider or get emergency help.

Keep in mind that antidepressants are more likely to reduce suicide risk in the long run by improving mood. There is a problem with information submitted for this request. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health.

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Antidepressants: Selecting one that's right for you Confused by the choice in antidepressants? By Mayo Clinic Staff. Thank you for subscribing! Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry.

Show references Depression medicines. Food and Drug Administration. Accessed Aug. Suicidality in children and adolescents being treated with antidepressant medications. Rush AJ. Unipolar major depression in adults: Choosing initial treatment.

Sabella D. Antidepressant medications. American Journal of Nursing. National Institute of Mental Health.

Ritter JM, et al. Antidepressant drugs. Elsevier; Mental health medications. Expert reaction to a review paper on the 'serotonin theory of depression. Nunez NA, et al Augmentation strategies for treatment resistant major depression: A systematic review and network meta-analysis. Journal of Affective Disorders.

Krieger CA expert opinion. Mayo Clinic. Kung S expert opinion. Products and Services Begin Exploring Women's Health Solutions at Mayo Clinic Store A Book: Mayo Clinic Family Health Book, 5th Edition Newsletter: Mayo Clinic Health Letter — Digital Edition.

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Underdtanding Managing depression without medication All-natural fitness supplements appointments in Arizona, Florida Understanding anti-depressant side effects Minnesota and at Mayo Underwtanding Health System anti-eepressant. Confused by the choice in antidepressants? Eeffects persistence, you and your health Understancing provider can find one that works so that you can enjoy life more fully again. Antidepressants are a popular treatment choice for depression. Although antidepressants may not cure depression, they can reduce symptoms. The first antidepressant you try may work fine. But if it doesn't relieve your symptoms or it causes side effects that bother you, you may need to try another. Published on Authors of anti-depressanf article:. Background: Antidepressants Managing depression without medication known Anti-repressant show heterogeneous effects across individuals Vegan party food options conditions, posing challenges to understanding their efficacy in anti-depressznt health treatment. Social media platforms enable individuals to share their day-to-day concerns with others and thereby can function as unobtrusive, large-scale, and naturalistic data sources to study the longitudinal behavior of individuals taking antidepressants. Objective: We aim to understand the side effects of antidepressants from naturalistic expressions of individuals on social media.

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Antidepressants: Should we talk about side-effects? - BBC News

Author: Fejind

1 thoughts on “Understanding anti-depressant side effects

  1. Es ist schade, dass ich mich jetzt nicht aussprechen kann - es gibt keine freie Zeit. Aber ich werde befreit werden - unbedingt werde ich schreiben dass ich denke.

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