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Macronutrients and blood sugar control

Macronutrients and blood sugar control

CGMs and Sensors. We're here bloof Macronutrients and blood sugar control. What aspects of macronutrient quantity and bpood impact glycemic control and cardiovascular disease CVD risk in people with diabetes? Jenkins DJ, Kendall CW, Augustin LS, et al. Huckvale K, Adomaviciute S, Prieto JT, et al. Diabetes Care ;—

Mayo Clinic offers appointments in Arizona, Adn and Minnesota and at Contorl Clinic Health Macdonutrients locations. A diabetes diet is a healthy-eating blod that helps control blood sugar.

Use shgar guide to get started, from meal planning to counting carbohydrates. A diabetes diet simply means eating the controo foods in ssugar amounts Body cleanse for overall wellness sticking to regular mealtimes.

It's a healthy-eating plan that's naturally rich in nutrients and low in Macronutrients and blood sugar control and calories. Key elements are fruits, vegetables and whole Macronutrients and blood sugar control.

In fact, Red pepper hash type of diet is the best eating contorl for most fontrol. If you have diabetes controol prediabetes, your Macrnoutrients care provider bloos likely recommend that you see Microbial resistance products dietitian to help you develop Macronnutrients Macronutrients and blood sugar control Heart health. The plan helps you control your blood sugar, also called blood glucose, manage your weight Macronturients control heart disease risk factors.

These factors include high Macronutrients and blood sugar control usgar and high blood blkod. When you eat extra calories and carbohydrates, your blood sugar levels rise. If blood sugar ad controlled, it Respiratory system functions lead to serious problems.

These adn include a high blood sugar level, called hyperglycemia. If this ans level lasts for conttrol long time, it may lead to long-term complications, such as nerve, Macronutrients and blood sugar control, kidney and shgar damage.

You can help keep your blood sugar level in Macrpnutrients safe range. Make healthy food contrrol and track Macronutriente eating habits. For most people with type Mactonutrients diabetes, weight loss also can make it easier Macronutrisnts control blood sugar.

Weight loss offers a host blooc other Macronutruents benefits. If you blooe to lose weight, a healthy-eating plan provides a well-organized, nutritious congrol to reach suggar goal safely.

A diet for people living with diabetes is vlood on eating healthy Macronytrients at regular times. Macronutroents meals at ahd times helps to better use insulin that Macrpnutrients body makes or gets through medicine.

A registered dugar can help you put together a bloo based Macronktrients your health goals, tastes and lifestyle. The dietitian bllod can talk wugar you about how to improve your eating habits. Options include choosing portion sizes that suit the Low GI side dishes for Metabolic syndrome obesity size and activity level.

Confrol your calories count with nutritious Macronuutrients. Choose healthy carbohydrates, fiber-rich foods, fish and "good" fats. During digestion, sugars and starches break down Glucose supplements blood glucose.

Sugars Maccronutrients are sygar as simple carbohydrates, and starches also are known as complex carbohydrates. Maxronutrients on healthy Macronutrientw, such as:.

Dietary fiber includes all parts Macronuttients plant foods that your body can't Macronutriejts or absorb. Fiber blpod how your body digests food Metabolic syndrome obesity helps control blood sugar blokd. Foods high in fiber include:.

Nad heart-healthy fish at least twice Macronutrients and blood sugar control week. Blold such as salmon, Macronuyrients, tuna and sardines are rich in omega-3 fatty acids. These omega-3s may prevent heart disease. Foods containing monounsaturated and polyunsaturated fats can help lower your cholesterol levels.

These include:. Diabetes raises your risk of heart disease and stroke by raising the rate at which you develop clogged and hardened arteries.

Foods containing the following can work against your goal of a heart-healthy diet. You may use a few different approaches to create a healthy diet to help you keep your blood sugar level within a typical range. With a dietitian's help, you may find that one or a combination of the following methods works for you:.

The American Diabetes Association offers a simple method of meal planning. It focuses on eating more vegetables.

Follow these steps when preparing your plate:. Because carbohydrates break down into sugar, they have the greatest effect on your blood sugar level.

To help control your blood sugar, you may need to learn to figure out the amount of carbohydrates you are eating with the help of a dietitian. You can then adjust the dose of insulin accordingly. It's important to keep track of the amount of carbohydrates in each meal or snack.

A dietitian can teach you how to measure food portions and become an educated reader of food labels. You also can learn how to pay special attention to serving size and carbohydrate content.

A dietitian may recommend you choose specific foods to help plan meals and snacks. You can choose a number of foods from lists that include categories such as carbohydrates, proteins and fats. One serving in a category is called a choice. A food choice has about the same amount of carbohydrates, protein, fat and calories — and the same effect on your blood sugar — as a serving of every other food in that same category.

For example, the starch, fruits and milk list includes choices that are all between 12 and 15 grams of carbohydrates. Some people who live with diabetes use the glycemic index to select foods, especially carbohydrates. This method ranks carbohydrate-containing foods based on their effect on blood sugar levels.

Talk with your dietitian about whether this method might work for you. When planning meals, take into account your size and activity level. The following menu is for someone who needs 1, to 1, calories a day. Embracing a healthy-eating plan is the best way to keep your blood sugar level under control and prevent diabetes complications.

And if you need to lose weight, you can tailor the plan to your specific goals. Aside from managing your diabetes, a healthy diet offers other benefits too. Because this diet recommends generous amounts of fruits, vegetables and fiber, following it is likely to lower your risk of cardiovascular diseases and certain types of cancer.

And eating low-fat dairy products can reduce your risk of low bone mass in the future. If you live with diabetes, it's important that you partner with your health care provider and dietitian to create an eating plan that works for you.

Use healthy foods, portion control and a schedule to manage your blood sugar level. If you don't follow your prescribed diet, you run the risk of blood sugar levels that change often and more-serious complications. There is a problem with information submitted for this request.

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Diabetes diet: Create your healthy-eating plan. Products and services. Diabetes diet: Create your healthy-eating plan A diabetes diet is a healthy-eating plan that helps control blood sugar.

By Mayo Clinic Staff. Related information Slide show: Healthy meals start with planning - Related information Slide show: Healthy meals start with planning Slide show: 10 great health foods - Related information Slide show: 10 great health foods.

Thank you for subscribing! Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. Show references Evert AB, et al. Nutrition therapy for adults with diabetes or prediabetes: A consensus report. Diabetes Care.

Eating right doesn't have to be boring. American Diabetes Association. Accessed Feb. What is the diabetes plate method?

: Macronutrients and blood sugar control

Evaluation of the Effect of Macronutrients Combination on Blood Sugar Levels in Healthy Individuals

There are three main types of carbohydrates in food: starches, sugars, and fiber. Learn about the types and what foods you can find them in.

Carb counting involves counting the number of grams of carbohydrate in a meal and matching that to your dose of insulin. Get the facts and learn how to do it.

Get up to speed on understanding food label, how food affects your glucose, and tips for planning healthy meals. Sometimes you can pinpoint a related food or activity, but not always. Breadcrumb Home Navigating Nutrition Understanding Carbs. Get smart on carbs. Carbohydrates in food There are three main types of carbohydrates in food—starches, sugar, and fiber.

When choosing carbohydrate foods: Eat the most of these: whole, unprocessed, non-starchy vegetables. Non-starchy vegetables like lettuce, cucumbers, broccoli, tomatoes, and green beans have a lot of fiber and very little carbohydrate, which results in a smaller impact on your blood glucose.

Remember, these should make up half your plate according to the Plate Method! Eat some of these: whole, minimally processed carbohydrate foods. These are your starchy carbohydrates, and include fruits like apples, blueberries, strawberries and cantaloupe; whole intact grains like brown rice, whole wheat bread, whole grain pasta and oatmeal; starchy vegetables like corn, green peas, sweet potatoes, pumpkin and plantains; and beans and lentils like black beans, kidney beans, chickpeas and green lentils.

Try to eat less of these: refined, highly processed carbohydrate foods and those with added sugar. These include sugary drinks like soda, sweet tea and juice, refined grains like white bread, white rice and sugary cereal, and sweets and snack foods like cake, cookies, candy and chips.

More About Carbs. There are 3 macronutrients in our diet — proteins, fat and carbohydrates. Out of these 3 macronutrients, carbohydrates also known as starches and sugars have the most effect on our blood sugar levels.

Protein and fat do not affect blood sugar directly, but they do play a role in diabetes management. Lets take a deeper look into all 3 of the macronutrients:.

There are 2 types of carbohydrates — simple and complex. Simple carbohydrates such as raw sugar, juice, etc are those that do not require a lot to be broken down into digestible parts.

These types of carbs usually cause a fast and high spike in our blood sugar. This is why most Registered Dietitians recommend pairing simple carbohydrates and actually all carbohydrates with a protein or a fat source. The addition of a protein or fat slows down the digestion of the carbohydrate because they these macronutrients require different enzymes for their breakdown.

Complex carbohydrates whole grains, fiber rich fruits and vegetables, beans take more time to be digested because of the starch and fiber content , therefore causing a slower rise in blood sugar, which is preferable in the management of diabetes.

Protein has a minimal effect on blood glucose levels if there is adequate insulin. In people who don't have diabetes, higher levels of amino acids signal the pancreas to produce the hormones glucagon and insulin.

Insulin stimulates your muscle cells to take up amino acids, and glucagon causes your liver to release stored sugar. As a result, blood sugar levels remain stable after protein consumption. However, with insulin deficiency as in those with Type 1 diabetes, and with those that have had type 2 diabetes for a long time , the pancreas still secretes glucagon when amino acids appear in the blood.

When there is no insulin to balance the glucagon, blood sugar levels rise as the liver releases stored sugar. Some individuals have found that if their diabetes is well controlled, large amounts of protein have the potential to contribute to glucose production, minimally increase blood glucose levels, and require additional small amounts of insulin.

Fat has little, if any, effect on blood glucose levels, although a high fat intake does appear to contribute to insulin resistance which would require more insulin. Many individuals on insulin pumps have seen this happen, where a high fat meal causes delayed hyperglycemia high blood sugar 3—5 hours after eating and they need additional insulin delivered over several hours.

Systematic review procedure

More About Carbs. Start Counting. More Resources Get up to speed on understanding food label, how food affects your glucose, and tips for planning healthy meals. Reading Food Labels. Learn More.

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J Am Heart Assoc. Foster-Powell K, Holt SH, Brand-Miller JC. International table of glycemic index and glycemic load values: Buyken, AE, Goletzke, J, Joslowski, G, Felbick, A, Cheng, G, Herder, C, Brand-Miller, JC.

Association between carbohydrate quality and inflammatory markers: systematic review of observational and interventional studies. The American Journal of Clinical Nutrition Am J Clin Nutr. AlEssa H, Bupathiraju S, Malik V, Wedick N, Campos H, Rosner B, Willett W, Hu FB.

Carbohydrate quality measured using multiple quality metrics is negatively associated with type 2 diabetes. The contents of this website are for educational purposes and are not intended to offer personal medical advice. You should seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

Never disregard professional medical advice or delay in seeking it because of something you have read on this website. The Nutrition Source does not recommend or endorse any products. Skip to content The Nutrition Source.

The Nutrition Source Menu. Search for:. Home Nutrition News What Should I Eat? As blood sugar levels rise, the pancreas produces insulin, a hormone that prompts cells to absorb blood sugar for energy or storage.

As cells absorb blood sugar, levels in the bloodstream begin to fall. When this happens, the pancreas start making glucagon, a hormone that signals the liver to start releasing stored sugar. This interplay of insulin and glucagon ensure that cells throughout the body, and especially in the brain, have a steady supply of blood sugar.

Type 2 diabetes usually develops gradually over a number of years, beginning when muscle and other cells stop responding to insulin. This condition, known as insulin resistance, causes blood sugar and insulin levels to stay high long after eating.

Over time, the heavy demands made on the insulin-making cells wears them out, and insulin production eventually stops. Complex carbohydrates: These carbohydrates have more complex chemical structures, with three or more sugars linked together known as oligosaccharides and polysaccharides.

Low-glycemic foods have a rating of 55 or less, and foods rated are considered high-glycemic foods. Medium-level foods have a glycemic index of Eating many high-glycemic-index foods — which cause powerful spikes in blood sugar — can lead to an increased risk for type 2 diabetes, 2 heart disease, 3 , 4 and overweight, 5 , 6 7.

There is also preliminary work linking high-glycemic diets to age-related macular degeneration, 8 ovulatory infertility, 9 and colorectal cancer.

blood glucose control to prevent further complications from developing i. loss of eye sight, loss of feeling in your exterior limbs, heart disease, kidney disease, etc. Therefore, it is essential to monitor the grams of carbohydrates a Diabetic is consuming per meal and snack time to control the amount of glucose going into their blood.

Seems pretty logical, right? What about the other two macros, protein and fat, are they important to control Diabetes?

Are all carbohydrates created equal? Absolutely not. They all vary in carbohydrate content and there are two different types of carbohydrates — complex carbs and simple carbs click the link to go to a previous post that goes in-depth about the different types of carbohydrates.

Fun fact: fiber slows down the release of sugar a. glucose into the blood. Meaning that if you consume more fibrous foods in your diet, you will have more blood sugar control! Pretty rad, right? They are more easily absorbed and utilized quickly as energy for the body.

This is also why simple carbohydrates do not leave you feeling full or satisfied for an extended period of time because of how fast they are utilized. Lastly, remember that varying carbohydrate content I mentioned earlier? If you need help establishing your carbohydrate gram goals or need more insight on any of this information, I can help.

Remember how I mentioned above that fiber slows down the release of sugar into the blood? Well, the same thing happens when you pair a carbohydrate with a fat and protein source! Pretty awesome stuff. Also, protein and fat are the two macronutrients that will leave you feeling full and satisfied until your next meal.

So tell me again, why are you not counting your macros to make sure that you are consuming a balanced diet and to better control your Diabetes? Pro tip: if you are not in the mood for a complex carb, no worries at all. Regardless of which carbohydrate you select to consume, every meal and snack should be balanced.

Types of Proteins To Consider Omega-3 fatty acids are usually evaluated as milligrams per day or as a distribution within the population rather than on the basis of percent of energy intake. Soy protein reduces serum LDL cholesterol and the LDL cholesterol:HDL cholesterol and apolipoprotein B:apolipoprotein A-I ratios in adults with type 2 diabetes. Effect of dietary pulse intake on established therapeutic lipid targets for cardiovascular risk reduction: A systematic reviewandmeta-analysis of randomized controlled trials. More recent analyses have assessed the relation of different fatty acids with CV outcomes. Unsaturated fats typically come from plant sources such as olives, nuts, or seeds, but are also present in fish. Effect of lowering the glycemic load with canola oil on glycemic control and cardiovascular risk factors: A randomized controlled trial.
When an Macronutrients and blood sugar control is Macronutrients and blood sugar control with Hydration tips 2 An, what Macronutriemts really Alpha-lipoic acid and aging is that the amount of glucose in their blood is high. Where does glucose come from? All carbohydrates. The main goal for a Diabetic should always be blood sugar a. blood glucose control to prevent further complications from developing i. loss of eye sight, loss of feeling in your exterior limbs, heart disease, kidney disease, etc.

Macronutrients and blood sugar control -

loss of eye sight, loss of feeling in your exterior limbs, heart disease, kidney disease, etc. Therefore, it is essential to monitor the grams of carbohydrates a Diabetic is consuming per meal and snack time to control the amount of glucose going into their blood.

Seems pretty logical, right? What about the other two macros, protein and fat, are they important to control Diabetes? Are all carbohydrates created equal? Absolutely not. They all vary in carbohydrate content and there are two different types of carbohydrates — complex carbs and simple carbs click the link to go to a previous post that goes in-depth about the different types of carbohydrates.

Fun fact: fiber slows down the release of sugar a. glucose into the blood. Meaning that if you consume more fibrous foods in your diet, you will have more blood sugar control!

Pretty rad, right? They are more easily absorbed and utilized quickly as energy for the body. This is also why simple carbohydrates do not leave you feeling full or satisfied for an extended period of time because of how fast they are utilized.

Lastly, remember that varying carbohydrate content I mentioned earlier? If you need help establishing your carbohydrate gram goals or need more insight on any of this information, I can help. Remember how I mentioned above that fiber slows down the release of sugar into the blood?

Well, the same thing happens when you pair a carbohydrate with a fat and protein source! Pretty awesome stuff.

Also, protein and fat are the two macronutrients that will leave you feeling full and satisfied until your next meal. So tell me again, why are you not counting your macros to make sure that you are consuming a balanced diet and to better control your Diabetes?

Pro tip: if you are not in the mood for a complex carb, no worries at all. Regardless of which carbohydrate you select to consume, every meal and snack should be balanced. When I say balanced, I mean that the meal or snack should include a carbohydrate option, a fat option, and a protein option for optimal blood sugar control.

Unsure of how to calculate your macro gram goals? I can help. First, ditch the guilt. When you over consume carbohydrates the best thing you can do is utilize them! You can achieve this by doing any type of cardio you prefer or simply going for a 30 — 60 minute walk after the meal.

To avoid low blood sugar, the best piece of advice I can give is to check your blood sugar daily. If you start to feel light headed at any given time and recognize the feeling of low blood sugar, this is not something to throw to the westside.

Either grab oz. These two sources are quick acting and will cause your blood sugar to spike, which is ideal in a low blood sugar situation. Wait about 15 minutes, test your blood sugar and assess how you are feeling. If your blood sugar is still too low, repeat the sugary drink or glucose step above, wait another 15 minutes and repeat the test.

Insulin sensitivity by euglycemic-hyperinsulinemic clamp improved in the lower-fat diet compared with the conventional diet in one study Two weight-loss RCTs by the same group compared meal replacements versus conventional diets 59 , 60 and found significant reductions in FBG over short durations with meal replacements.

One study carried out for 12 months showed no persistent difference in FBG between groups, although significantly more subjects in the meal replacement group had reductions in diabetic medications In addition to the information from the clinical trials, a cross-sectional study 61 found that higher-fat intake correlated with significantly higher A1C.

Of the seven studies that measured CVD risk factors, only one had significant findings. The cross-sectional study 61 found that higher-fat intake correlated with higher levels of total cholesterol and LDL cholesterol as well as coronary artery calcium.

Lowering total fat intake infrequently improved glycemic control or CVD risk factors in clinical trials involving individuals with diabetes. Lowering fat intake in individuals with diabetes may improve total cholesterol and LDL cholesterol but may also lower HDL cholesterol.

For this review, the type of fat refers to the proportion of total energy from a specific fatty acid or fatty acid category. Categorization may be on the basis of the number of, the location of, or the configuration of double bonds. Saturated fatty acids SFAs may be assessed based on distribution within the study population or recommended dietary levels.

Omega-3 fatty acids are usually evaluated as milligrams per day or as a distribution within the population rather than on the basis of percent of energy intake.

One RCT in individuals with type 2 diabetes compared glycemic control outcomes for SFAs versus MUFAs with the total fat remaining equal 62 and did not find a significant difference between diets for postprandial glucose or insulin response. An intriguing idea for future research is that lowering SFA or increasing MUFA may increase glucagon-like peptide-1 activity, thereby reducing postprandial TG.

Three blinded RCTs in individuals with type 2 diabetes 63 — 65 found that omega-3 fatty acid supplements may increase FBG by a small but significant amount.

However, a fourth blinded RCT 66 observed a significant decrease in A1C with supplementation compared with controls.

In the meta-analysis by Hartweg et al. One of these studies 64 also found a decrease in the HDL-3 fraction with EPA supplementation. One study 73 focused on whole-food omega-3 intake in a prospective cohort and found that baseline marine omega-3 fatty acid intake was inversely associated with TG.

Overall it appears that supplementation with omega-3 fatty acids does not improve glycemic control but may have beneficial effects on CVD risk biomarkers among individuals with type 2 diabetes by reducing TGs in some but not all studies. Other benefits e. This section reviews studies examining the effects of varying the amount of daily protein intake or the source of protein intake and further distinguishes those studies that included individuals with diabetic kidney disease DKD.

Durations of follow-up ranged from 4 to 16 weeks, and sample sizes were small range 12—29 participants in the higher-protein intervention. A 5-week weight-maintenance study 25 observed a significant reduction in A1C and h glucose response and significantly lower fasting TGs on the higher- versus lower-protein eating patterns.

A study of 8 weeks of weight loss followed by 4 weeks of weight maintenance 74 found no significant differences between higher- and lower-protein groups for A1C; however, significant decreases in serum total cholesterol and LDL cholesterol were observed on the higher- versus lower-protein diets.

Another study 23 and a 1-year follow-up of the Parker and colleagues study 24 reported no significant differences between groups in glycemic control or CVD risk factors.

Four parallel RCTs examined the effects of lower versus usual protein intake on glycemic control, CVD risk factors, and renal function markers in individuals with types 1 and 2 diabetes and microalbuminuria 75 , macroalbuminuria 76 , 77 , or both One study blinded physicians to diet treatment Two studies achieved lower protein intakes of 0.

None of the studies found significant differences between groups for glycemia, CVD risk factors, or renal function glomerular filtration rate [GFR], various measures of proteinuria.

At the levels of protein achieved, no reduction in serum albumin was noted. Two meta-analyses addressed protein restriction in people with diabetes and micro- and macroalbuminuria.

The meta-analysis by Pan et al. These four studies 75 — 78 are included above. Four RCTs examined the effects of source of protein intake on glycemic control, CVD risk factors, and renal function in individuals with type 2 diabetes and microalbuminuria 81 or macroalbuminuria 82 — Durations of follow-up ranged from 4 weeks to 4 years, and sample sizes were small 14—20 participants in the designated source interventions.

The nutrition source focus for two RCTs was soy. HDL cholesterol increased significantly and urinary albumin-to-creatinine ratio decreased significantly with soy powder versus casein powder supplementation For individuals with DKD and either micro- or macroalbuminuria, reducing the amount of protein from normal levels does not appear to alter glycemic measures, CVD risk measures, or the course of GFR.

For individuals with DKD and macroalbuminuria, changing the source of protein to be more soy based may improve CVD risk measures but does not appear to alter proteinuria.

The high MUFA content of most tree nuts and peanuts and high PUFA content of walnuts and pine nuts lends support to the investigation of potential effects of nuts on glycemic control and CVD risk in individuals with diabetes.

Since , three RCTs and two reports from the NHS have been published on this topic 30 , 85 — All studies analyzed participants according to treatment assignment, and two studies blinded participants to treatment.

Two RCTs 85 — 87 tested the effects of walnuts against general advice or advice to consume specific PUFA-rich foods. There were no significant differences among groups for glycemic control. Results relating to measures of CVD risk were mixed. Addition of walnuts led to no significant differences in total cholesterol and LDL cholesterol; however, improved endothelial function was observed In another study 86 , the walnut group achieved significant reductions in LDL cholesterol and increases in HDL cholesterol and the ratio of HDL-to-total cholesterol relative to the other treatment groups.

However, a third study 30 found that HDL cholesterol was significantly lower in the group receiving almonds vs. These authors concluded that total dietary fat had a greater effect on serum lipids than did fat source Two cross-sectional studies reported associations between nut consumption and lower-risk CVD risk markers.

Consumption of at least five servings per week of nuts or peanut butter was significantly associated with a more favorable lipid profile lower total cholesterol, LDL cholesterol, and apoB There were no significant associations for inflammatory markers Nut-enriched diets do not alter glycemia in individuals with diabetes.

The evidence is mixed as to whether they have beneficial effects on serum lipoproteins. Two single-blinded crossover RCTs compared whole grains to fiber 47 , 48 in individuals with type 2 diabetes.

Whole-wheat flour products did not change glycemic measures over 5 weeks, while adding fiber arabinoxylan to whole-wheat flour products resulted in significantly lower postprandial glucose, insulin, and fructosamine In the second RCT, A1C and FBG were not altered significantly over 12 weeks with Salba a novel whole grain or wheat bran Neither study found significant differences in CVD risk markers.

Two cross-sectional analyses from the NHS found that higher intake of whole grains was associated with lower levels of markers of inflammation CRP and TNF-R2 54 and with higher adiponectin concentrations One of the RCTs also found CRP was significantly lower in the whole grain versus the wheat bran groups Whole-grain consumption does not appear to be associated with improved glycemic control in individuals with diabetes.

However, diets high in whole grains may reduce systemic inflammation. Two crossover and four parallel RCTs 50 , 60 , 91 — 95 investigated the effects of soy-based supplements on individuals with type 2 diabetes.

One of the above RCTs reported glycemic and CVD information in separate publications 91 , Five of the six studies found no significant difference in glycemic measures between groups 92 , 93 50 , 94 60 ; however, two studies observed improvements in LDL cholesterol 91 , 93 or total cholesterol 93 versus control.

A diet-counseling, randomized crossover trial 52 found that legumes as part of a moderately high—carbohydrate, high-fiber, and lower-GI diet improved postprandial glucose and CVD risk factors compared with a higher-MUFA diet. Three crossover RCTs compared soy protein for effects on glycemic and CVD risk markers in postmenopausal women with type 2 diabetes 96 — Duration of follow-up ranged from 4 to 12 weeks, sample sizes were small 16—32 , and all studies were double-blinded.

Two studies found no significant differences between groups in glycemic control measures or lipoproteins 97 , 98 , and one of these found no difference in CRP or HOMA-insulin resistance IR However, the third 96 showed significant reductions in A1C, fasting insulin, HOMA-IR, total cholesterol, and LDL cholesterol in the soy group compared with the control group.

While the soy-derived supplements in the studies were quite different, most studies did not indicate a significant reduction in glycemic measures or CVD risk factors compared with controls.

One small short-term RCT addressed vegetable supplements in individuals with type 2 diabetes. At four weeks, garlic powder tablets significantly improved FBG, fructosamine, and TGs Higher-fiber vegetables as part of a moderately high—carbohydrate, high-fiber, and lower-GI diet improved postprandial glucose and CVD risk factors compared with a higher-MUFA diet In women with type 2 diabetes, vegetables and fruit as a component of the Mediterranean-style eating pattern score were not associated with adiponectin concentrations Eating pattern research has not directly addressed the role of vegetables and fruits in people with diabetes.

Of the few studies found since , results are mixed. Five RCTs two crossover and three parallel feeding trials examined the effects of dairy supplements on glycemic control and CVD risk factors one RCT reported glycemic and CVD information in separate publications 91 , Three studies included adults with type 2 diabetes and one included youths with type 1 diabetes Duration of follow-up ranged from 6 to 52 weeks, and sample sizes ranged from 11 to 59 participants per study group.

Three RCTs comparing soy to dairy 91 — 94 found no significant differences between groups in glycemic control. However, two of the studies 91 , 93 did find LDL cholesterol to be significantly higher for the milk protein isolate 91 and casein 93 groups vs.

the soy groups. An ancillary report of a weight-loss study found that there was no relationship between dairy calcium and glycemic control or CVD risk markers. None of the components of dairy appear to have an effect on glycemic control or CVD risk reduction. There were no significant differences among groups for FBG, LDL cholesterol, and HDL cholesterol.

Total cholesterol was significantly lower after the chicken and the vegetable protein diet versus the red meat diet, and TGs were significantly lower after the chicken diet versus the red meat diet and the vegetable protein diet.

In women with type 2 diabetes in the NHS , a high intake of red meat was significantly associated with fatal coronary heart disease, coronary revascularization, and total coronary heart disease.

Currently, there is limited evidence to provide conclusive statements relating to the intake of meat, poultry, and fish.

Research involving diabetes and food groups is sparse and does not indicate an advantage for specific foods in improving glycemic control. There is a possibility that certain CVD risk factors could be improved with the consumption of nuts or whey. Eating patterns include—but are not limited to—lower carbohydrate, lower fat, lower GI see the respective sections in Question 1 as well as Mediterranean and vegetarian.

Five RCTs 52 , — compared a Mediterranean or modified Mediterranean-style eating pattern to other eating patterns over a period of 4 weeks to 4 years. Weight loss was similar, and there were no significant differences in glycemic control between groups.

Adiponectin increased similarly with both eating patterns. De Natale et al. Three RCTs comparing Greek traditional or fast foods found no significant differences between groups for glycemic control and CVD risk factors — A cross-sectional study 88 and a case-control study examined the Mediterranean-style eating pattern to address how adherence was related to selected biomarkers.

There were no significant differences between adherence tertiles for A1C 88 , , total cholesterol 88 , , or LDL cholesterol The NHS 88 found that adherence to the Mediterranean-style eating pattern was associated with higher plasma adiponectin concentrations in women with diabetes, and this was attributed mainly to the intake of alcohol, nuts, and whole grains.

An RCT compared 4 oz. of red wine daily to no alcohol. Fasting insulin and HOMA decreased in both groups, with the wine group having a significantly greater decrease.

Both groups significantly reduced total cholesterol and LDL cholesterol with no change in TG. HDL cholesterol was significantly increased in the wine group only, whereas markers of inflammation TNF, CRP, and others were significantly increased in the control group.

There appears to be no advantage in using the Mediterranean-style eating pattern compared with other eating patterns for glycemic control. There are mixed results for CVD risk factors with some studies indicating that the Mediterranean-style eating pattern might improve HDL cholesterol and TG.

One RCT 21 , comparing a low-fat vegan eating pattern and a conventional eating pattern found that weight and A1C decreased in both groups, with no significant difference between groups in the primary analyses.

In an ancillary analysis that removed participants who did not complete follow-up or who had medications changed during follow-up, there was a significantly greater decrease in A1C and LDL cholesterol in the vegan group.

In a 4-week crossover RCT in individuals with early DKD, a lacto-vegetarian eating pattern did not show significant differences in FBG, HDL cholesterol, or LDL cholesterol; however, total cholesterol significantly decreased compared with the usual eating pattern, and GFR significantly decreased compared with both the usual and chicken diets 81 , Research is limited regarding vegetarian eating patterns.

Because of methodological problems, more research is needed before conclusive remarks can be made about the associations between a vegetarian eating pattern and glycemic control and CVD risk factors.

Studies examining how eating patterns are related to glycemic control and CVD risk markers have varied with respect to macronutrient distribution used to characterize low-fat, Mediterranean, low-GI, vegetarian, and lower-carbohydrate eating patterns.

While some research suggests that these eating patterns improve glycemic and cardiovascular outcomes, variability in research methods and definitions have complicated interpretation of findings. Issues that could affect conclusions include retention rates, dietary intervention and assessment methodology, and data analysis approaches.

Variability in study methodology, including measurement of dietary intake, retention rates, and confounding by weight loss, limits comparisons as to how macronutrient distribution independent of weight loss affects outcomes of interest.

The evidence presented in this review suggests that many different approaches to MNT and eating patterns are effective for the target outcomes of improved glycemic control and reduced CVD risk among individuals with diabetes.

However, several gaps in the literature remain that warrant mentioning here. Most of the studies in the present review examined the relationship of macronutrients and foods to biochemical markers of glycemic control and CVD risk.

While research has long explored the mechanisms underlying the relationship between nutrition and glycemia, studies have only just begun examining how nutrition relates to the endocrine functions of fat tissue and other cardiovascular parameters. For example, future studies should address:.

The role of adiponectin, which may be responsive to changes in eating patterns and has been associated with better diabetes-related health outcomes in epidemiological studies. The role of omega-3 fatty acids in relation to adipose tissue inflammation, thrombosis, and lipid metabolism in the context of observations that higher intakes are associated with reduced CVD mortality, particularly sudden cardiac death.

The impact of very-low-carbohydrate and moderately low—carbohydrate eating patterns on long-term complications such as nephropathy. The impact of postprandial excursions and hyperglycemia on inflammatory response and subsequent CVD risk.

In addition to these biochemical mechanisms underlying nutrition-related CVD risk, the interplay between specific nutrients and dietary macronutrient composition has yet to be thoroughly evaluated. The use of technology such as continuous glucose monitors to evaluate the impact of macronutrients in isolation, in the presence of specific nutrients, in the context of a mixed meal, and in overall eating patterns must be elucidated in order to fully understand how diet impacts glycemic control.

Moving forward, it is essential to consider that individuals benefit differently from various nutritional approaches.

Related to this tailored approach to MNT, it should be noted that individual adherence to nutrition recommendations is highly variable—and generally suboptimal. Research is needed to develop strategies that enhance adherence and to determine if certain nutritional approaches promote greater adherence than others.

Continued support is needed for large, multicenter trials with clinical event end points. Diabetes care involves monitoring risk factors for both macrovascular and microvascular complications and therefore the sample size needed to detect multiple biologically and clinically relevant effect sizes requires special consideration.

Furthermore, the duration of follow-up needs to be adequate relative to the outcomes of interest, and strategies should be used to improve retention. Study design and statistical analyses should consider time-varying factors, such as changes in weight and medications, which may independently impact study outcomes, especially in small-scale efficacy trials.

Finally, due to the large volume and variety of research regarding diet and diabetes-related health outcomes, rigorous systematic reviews and meta-analyses need to be conducted so that researchers, clinicians, patients, and funding agencies are aware of the most recent research and the direction in which it is heading.

has reported being a member of the Research Committee for the American Pistachio Growers. No other potential conflicts of interest relevant to this article were reported.

researched data, contributed to discussion, and wrote, reviewed, and edited the manuscript. contributed to discussion and wrote, reviewed, and edited the manuscript. reviewed and edited the manuscript. researched data, contributed to discussion, and reviewed and edited the manuscript. The authors thank M.

Sue Kirkman, MD, for her input into the manuscript and the former University of North Carolina students for conducting the initial literature search: Emily Ford, MPH, RD; Natalie Peterson, MPH, RD; Cassandra Rico, MPH, RD; Carolyn Wait, MPH, RD; and John Yoon, BS.

Sign In or Create an Account. Search Dropdown Menu. header search search input Search input auto suggest. filter your search All Content All Journals Diabetes Care. Advanced Search. User Tools Dropdown. Sign In. Skip Nav Destination Close navigation menu Article navigation. Volume 35, Issue 2.

Previous Article Next Article. Systematic review procedure. Challenges in evaluating macronutrient studies in diabetes management. Question 1: What aspects of macronutrient quantity and quality impact glycemic control and CVD risk in people with diabetes?

Carbohydrate amount. Carbohydrate type. Fat amount. Fat type. Question 2A: How do macronutrients combine in food groups to affect glycemic response and CVD risk reduction in people with diabetes?

Whole grains. Vegetables and fruit. Meats, poultry, and fish. Question 2B: How do macronutrients combine in eating patterns to affect glycemic response and CVD risk factors in people with diabetes?

Vegetarian eating pattern. Question 3: Is there an optimal macronutrient ratio for glycemic management and cardiovascular risk reduction in people with diabetes?

Question 4: What should guide the future directions of research? Article Navigation. Systematic Review January 16 Macronutrients, Food Groups, and Eating Patterns in the Management of Diabetes : A systematic review of the literature, Madelyn L. Wheeler, MS ; Madelyn L. Wheeler, MS. This Site. Google Scholar.

Stephanie A. Dunbar, MPH ; Stephanie A. Dunbar, MPH. Corresponding author: Stephanie A. Dunbar, sdunbar diabetes. Lindsay M. Jaacks, BS ; Lindsay M. Jaacks, BS. Wahida Karmally, DRPH ; Wahida Karmally, DRPH. Elizabeth J.

Mayer-Davis, MSPH ; Elizabeth J. Mayer-Davis, MSPH. Judith Wylie-Rosett, EDD ; Judith Wylie-Rosett, EDD. William S. Yancy, Jr. Diabetes Care ;35 2 — Get Permissions. toolbar search Search Dropdown Menu. toolbar search search input Search input auto suggest.

What findings and needs should direct future research? Evidence-based nutrition practice guidelines for diabetes and scope and standards of practice. Search ADS. American Dietetic Association.

Diabetes type 1 and 2 evidence-based nutrition practice guidelines for adults [article online], Chicago, IL. Accessed 10 November The evidence for medical nutrition therapy for type 1 and type 2 diabetes in adults.

Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association. Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications.

Association of diet with glycated hemoglobin during intensive treatment of type 1 diabetes in the Diabetes Control and Complications Trial. UKPDS estimated dietary intake in type 2 diabetic patients randomly allocated to diet, sulphonylurea or insulin therapy.

Action for Health in Diabetes Look AHEAD trial: baseline evaluation of selected nutrients and food group intake. Trends in nutrient intake among adults with diabetes in the United States: Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes.

Short-term effects of severe dietary carbohydrate-restriction advice in type 2 diabetes—a randomized controlled trial. Comparative study of the effects of a 1-year dietary intervention of a low-carbohydrate diet versus a low-fat diet on weight and glycemic control in type 2 diabetes. A low-carbohydrate diet is more effective in reducing body weight than healthy eating in both diabetic and non-diabetic subjects.

The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial. The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus.

Effects of a low-carbohydrate diet on glycemic control in outpatients with severe type 2 diabetes. Beneficial effect of low carbohydrate in low calorie diets on visceral fat reduction in type 2 diabetic patients with obesity. The Canadian Trial of Carbohydrates in Diabetes CCD , a 1-y controlled trial of low-glycemic-index dietary carbohydrate in type 2 diabetes: no effect on glycated hemoglobin but reduction in C-reactive protein.

Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study. A low-fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, wk clinical trial. Effects of a low-fat diet compared with those of a high-monounsaturated fat diet on body weight, plasma lipids and lipoproteins, and glycemic control in type 2 diabetes.

A high-protein diet with resistance exercise training improves weight loss and body composition in overweight and obese patients with type 2 diabetes. Long-term effects of advice to consume a high-protein, low-fat diet, rather than a conventional weight-loss diet, in obese adults with type 2 diabetes: one-year follow-up of a randomised trial.

Macronutriehts L. ContrilStephanie A. DunbarLindsay M. JaacksMacronutrients and blood sugar control Karmally Exquisite Fruit Arrangements, Elizabeth J. Mayer-DavisJudith Wylie-RosettWilliam S. Yancy; Macronutrients, Food Groups, and Eating Patterns in the Management of Diabetes : A systematic review of the literature, Diabetes Care 1 February ; 35 2 : —

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