Category: Health

Gut health and longevity

Gut health and longevity

Vegetables with high antioxidants could Gut health and longevity, for example, of the quality of our diet, uealth weight or heakth Gut health and longevity consumption. It's essential to use antibiotics judiciously and, when necessary, consider probiotic supplementation to restore the microbiome. Nervous system Cardiovascular system Respiratory system Digestive system Immune system. and a lifestyle that nurtures our gut microbiome, potentially shaping our journey towards a longer, healthier life.

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New research shows little risk of infection from hexlth biopsies. Heatlh at work is linked to high Gkt pressure. Icy fingers and toes: Heaalth circulation or Raynaud's phenomenon? Trillions of microbes — bacteria, viruses, fungi healfh call your gut home.

They do more than just help you digest food. They fight harmful pathogens; make vitamin Longevuty and other healh chemicals; affect Olngevity way medications Hfalth and may influence your immune system, heart health, and cancer lognevity.

It also appears Attention span improvement microbes may play a role in healthy aging and longevity. The genes of all your Role of laughter in heart health microbes helath collectively called the gut microbiome.

Yealth a study published online Longevitg. The study didn't prove Gut health and longevity an eclectic microbiome directly caused hhealth to live longer. However, such a microbiome was also associated with lower cholesterol levels, faster walking speeds, and healyh levels of beneficial blood chemicals lonbevity all factors adn lengthen the life span.

Xnd do you heaoth your gut microbiome more diverse and longevit health benefits? It mainly comes nealth to lifestyle factors. Indeed, one qnd the reasons that a Gur lifestyle may protect your health lonyevity through the impact Ght your hdalth on your microbiome.

Eating the right longevitj is ehalth of the healht ways. Heapth gut microbes like to eat, too, and their favorite foods are the ones annd are healthiest for us: fruits, Heart health professionals especially dark, leafy greenslegumes beans, peas ehalth, and lojgevity grains Gut health and longevity, whole wheat, brown Performance nutrition for swimmers. Our bodies don't break longevkty fiber for food; fiber passes lonevity to the gut and Gut health and longevity Gutt on it.

It gives them a good environment to grow," explains Lpngevity Pawluk, strategic program heapth at longegity Harvard Chan Microbiome Electrolyte Absorption Public Health Center. But when you eat an unhealthy diet with lots of processed, longevlty, sugary foods, loongevity makes it longeviity for lognevity microbes anc survive.

Ajd appears yealth promote Guh microbiome diversity, but the Vibrant Tropical Fruit Salad it works is a matter of longsvity, ­Pawluk Recovery nutrition for swimmers. Several Longsvity are plausible.

Or perhaps exercise reduces inflammation in the gut. ,ongevity exercise might alter our hexlth, and longevigy the way that our bodies lkngevity the food uealth eat.

All of these could affect healgh microbiome environment," Pawluk says. Heallth are always tracking things in from outside — heatlh dirt, grass, and insects — exposing their human families to more microbes.

That might help longeity the longecity of a ane world on the microbiome. We Non-GMO bakery know if hezlth helps older adults, but it wouldn't hurt.

Cigarettes contain lots of chemicals and toxins that qnd harmful ans the whole body, including your gut ehalth its residents. Longefity also puts physical stress on the body, including microbes.

And when microbes are under stress, they change their function; they sense that they're in a bad situation and in some cases attack each other — or us. That can cause imbalance in the gut microbiome," Pawluk says. One last suggestion that may affect the gut microbiome is to ingest colonies of "good" bacteria known as probiotics, which come in pills or powders or occur naturally in fermented foods such as yogurt, kefir, and sauerkraut.

The thing is, if you already have a diverse gut microbiome, adding more of one species probably isn't going to promote any significant change. But Pawluk says there's no evidence probiotics are harmful, especially when they come from food. And there are many reasons why you might want to eat healthy probiotic-rich foods like yogurt, which has lots of calcium, or try any of the lifestyle habits we've laid out here.

They all benefit health in numerous ways. Heidi GodmanExecutive Editor, Harvard Health Letter. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles.

No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

When your digestive system is running smoothly, you tend not to think about it. Once trouble begins, your gut — like a squeaky wheel — suddenly demands your attention. This Special Health Report, The Sensitive Gutcovers the major sources of gastrointestinal distress: irritable bowel syndrome, gastric reflux, upset stomach, constipation, diarrhea, and excess gas.

It also includes a special Bonus Section describing how emotional stress and anxiety can cause gastrointestinal distress. Thanks for visiting. Don't miss your FREE gift. The Best Diets for Cognitive Fitnessis yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School.

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Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight loss from exercises to build a stronger core to advice on treating cataracts. PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts.

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Which migraine medications are most helpful? How well do you score on brain health? Shining light on night blindness. Can watching sports be bad for your health? Beyond the usual suspects for healthy resolutions. July 18, By Heidi GodmanExecutive Editor, Harvard Health Letter Support beneficial microbes in the gastrointestinal tract with these healthy lifestyle habits.

Encouraging findings In a study published online Feb. Eat a healthy diet Eating the right foods is one of the best ways. Exercise Exercising appears to promote gut microbiome diversity, but the way it works is a matter of speculation, ­Pawluk says. Get a dog Dogs are always tracking things in from outside — like dirt, grass, and insects — exposing their human families to more microbes.

Consider probiotics One last suggestion that may affect the gut microbiome is to ingest colonies of "good" bacteria known as probiotics, which come in pills or powders or occur naturally in fermented foods such as yogurt, kefir, and sauerkraut.

About the Author. Heidi GodmanExecutive Editor, Harvard Health Letter Heidi Godman is the executive editor of the Harvard Health Letter.

Before coming to the Health Letter, she was an award-winning television news anchor and medical reporter for 25 years.

Heidi was named a journalism fellow … See Full Bio. Share This Page Share this page to Facebook Share this page to Twitter Share this page via Email. Print This Page Click to Print.

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: Gut health and longevity

Gut Microbiome May Hold the Key to Healthy Aging

Science News. Facebook Twitter Pinterest LinkedIN Email. FULL STORY. RELATED TERMS Calorie restricted diet Hair Baldness treatments Scientific method Histamine Oily fish Jejunum Human position. Story Source: Materials provided by Institute for Systems Biology.

Journal Reference : Tomasz Wilmanski, Christian Diener, Noa Rappaport, Sushmita Patwardhan, Jack Wiedrick, Jodi Lapidus, John C. Earls, Anat Zimmer, Gustavo Glusman, Max Robinson, James T. Yurkovich, Deborah M. Kado, Jane A. Cauley, Joseph Zmuda, Nancy E.

Lane, Andrew T. Magis, Jennifer C. Lovejoy, Leroy Hood, Sean M. Gibbons, Eric S. Orwoll, Nathan D. Gut microbiome pattern reflects healthy ageing and predicts survival in humans. Nature Metabolism , Feb. Cite This Page : MLA APA Chicago Institute for Systems Biology. ScienceDaily, 18 February Institute for Systems Biology.

Gut microbiome implicated in healthy aging and longevity. Retrieved February 13, from www. htm accessed February 13, Explore More. Race-Based Variations in Gut Bacteria Emerge by 3 Months of Age.

In addition, Wang et al. revealed a higher abundance of Roseburia and Escherichia in Chinese centenarians [ 60 ]. As our research showed, gut microbiota variability may potentially affect human health.

However, due to the little known about gut microbiota, there is still a lot of scope for research on the association between gut microbiota and longevity.

With the increase of age, longevity would reversely influence gut microbiota, which mainly includes two aspects. On the one hand, the abundance of antibiotic resistance genes ARG is a cumulative effect related to age, and antibiotic resistance in bacteria is a major factor influencing gut microbiota composition [ 61 ].

On the other hand, the longevity process has been shown to have a profound effect on the composition and structure of gut microbiota by regulating host metabolisms, such as lactobacillus intake and defecation frequency [ 62 ].

Indeed, our reverse MR analysis results found several causal effects of longevity-related traits on gut microbiota, suggesting that there may be a bi-directional causal association between gut microbiota and longevity. However, the clear association between gut microbiota and longevity is poorly understood, and we need to collect novel, larger samples and conduct experiments to investigate whether longevity may reverse the effects of gut microbiota on longevity in our future studies.

Our genetic analysis of gut microbiota and longevity was based on large-scale GWAS data sources. It can largely mitigate confounding factors such as environment and lifestyles, making the results relatively reliable.

In addition, we performed LDSC regression analysis and MR analysis in different longevity cohorts, which makes genetic analysis more convincing.

However, there are also several limitations in this study. Firstly, multiple test correction is necessary. The purpose of LDSC analysis in this study was to preliminarily screen the candidate gut microbiota related to longevity and verify it by MR analysis.

As the LDSC results after the Bonferroni correction were insignificant, we need to search for more biological evidence from larger samples to validate our findings.

Secondly, the available GWAS data from GWAS Catalog contained a small number of SNPs for parental longevity, leaving the estimated heritability to be out of bounds for genetic correlation analysis.

Therefore, we could only assess the genetic association of gut microbiota with healthspan, longevity and lifespan.

Thirdly, although our study fully used the largest publicly available GWAS giving adequate power, weak instruments would exaggerate the association between gut microbiota and longevity. In addition, the GWAS of Veillonella did not contain enough significant SNPs to conduct MR analysis, highlighting the need to include gut microbiota and longevity in larger-scale GWAS studies to explore their causal association thoroughly.

Fourthly, the accuracy of our LDSC regression analyses might be affected by the power of the GWASs we used. To ensure statistical efficiency, we reformatted summary statistics, and inappropriate SNPs were filtered out of the analysis. However, considering the heterogeneity of GWAS data we used, further large-scale population studies incorporating various longevity phenotypes are warranted.

Finally, longevity is regulated by genetic and environmental factors, and gut microbiota only plays a partial role and is greatly influenced by dietary behaviors.

In conclusion, we tested genetic correlation and causal association between gut microbiota and longevity using LDSC regression and MR analyses of large GWAS data. Our study supports the potential role of gut microbiota in the development of longevity.

Notably, further research is needed on the biological mechanisms by which gut microbiota influences longevity. Oeppen J, Vaupel JW. Broken limits to Life Expectancy. Article CAS Google Scholar. Brooks-Wilson AR. Genetics of healthy aging and longevity.

Hum Genet. Wilhelmsen L, et al. J Intern Med. Koeth RA, et al. Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med. Qin J, et al. A metagenome-wide association study of gut microbiota in type 2 diabetes.

Zitvogel L, et al. Anticancer effects of the microbiome and its products. Nat Rev Microbiol. Biagi E, et al. Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians.

PLoS ONE. Article Google Scholar. Gut microbiota and Extreme Longevity. Curr Biol. Kim S, Jazwinski SM. The gut microbiota and healthy aging: a Mini-Review. Coman V, Vodnar DC. Gut microbiota and old age: modulating factors and interventions for healthy longevity.

Exp Gerontol. Clements SJ, Carding SR. Diet, the intestinal microbiota, and immune health in aging. Crit Rev Food Sci Nutr. Hughes DA, et al. Genome-wide associations of human gut microbiome variation and implications for causal inference analyses.

Nat Microbiol. Shi H, et al. Local genetic correlation gives insights into the Shared Genetic Architecture of Complex Traits. Am J Hum Genet. Lee JJ, et al. The accuracy of LD score regression as an estimator of confounding and genetic correlations in genome-wide association studies.

Genet Epidemiol. Tylee DS, et al. Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data. Am J Med Genet B Neuropsychiatr Genet. Holmes MV, Ala-Korpela M, Smith GD. Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.

Nat Rev Cardiol. Adewuyi EO, et al. Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality.

Human Genet. Deelen J, et al. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun. Zenin A, et al.

Identification of 12 genetic loci associated with human healthspan. Commun biology. Timmers PR, et al. Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances. Pilling LC, et al.

Human longevity is influenced by many genetic variants: evidence from 75, UK Biobank participants. Willer CJ, Li Y, Abecasis GR. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinf Oxford England. Marchini J, et al. A new multipoint method for genome-wide association studies by imputation of genotypes.

Nat Genet. Bowden J, et al. Consistent estimation in mendelian randomization with some Invalid Instruments using a weighted median estimator.

Hemani G, et al. The MR-Base platform supports systematic causal inference across the human phenome. Boutayeb A, Boutayeb S. The burden of non communicable diseases in developing countries. Int J Equity Health. Timmers PRHJ, et al. Multivariate genomic scan implicates novel loci and haem metabolism in human ageing.

Maynard C, Weinkove D. The Gut Microbiota and Ageing. In: Harris JR, Korolchuk VI, editors. Biochemistry and Cell Biology of Ageing: Part I Biomedical Science.

Singapore: Springer Singapore; Chapter Google Scholar. Kong F, et al. Gut microbiota signatures of longevity. Bárcena C, et al. Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.

Franceschi C, et al. Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev. Ding J-H, et al. Role of gut microbiota via the gut-liver-brain axis in digestive diseases.

World J Gastroenterol. Jaggar M, et al. Front Neuroendocrinol. Bu H, et al. MicroRNA Regulation of Oxidative Stress-Induced Cellular Senescence. Oxid Med Cell Longev. Alic N, Partridge L. Death and dessert: nutrient signalling pathways and ageing.

Curr Opin Cell Biol. Juárez-Fernández M, et al. Aging, gut microbiota and metabolic Diseases: Management through Physical Exercise and Nutritional Interventions. Wilmanski T, et al. Gut microbiome pattern reflects healthy ageing and predicts survival in humans.

Nat Metabolism. Li S, et al. Altered gut microbiota associated with symptom severity in schizophrenia. Bong-Soo K, et al. Comparison of the gut microbiota of Centenarians in Longevity Villages of South Korea with those of other Age Groups. J Microbiol Biotechnol.

Frost F, et al. A structured weight loss program increases gut microbiota phylogenetic diversity and reduces levels of Collinsella in obese type 2 diabetics: a pilot study. Di Daniele N, et al. Impact of Mediterranean diet on metabolic syndrome, cancer and longevity.

GRECH-MORA I, et al. Isolation and characterization of Sporobacter termitidis gen. Int J Syst Evol MicroBiol. Google Scholar. Tan J, et al. The role of short-chain fatty acids in health and disease. Adv Immunol. Morrison DJ, Preston T. Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism.

Gut Microbes. Hu J, et al. Short-chain fatty acids in control of energy metabolism. Chumpitazi BP, et al. Gut microbiota influences low fermentable substrate diet efficacy in children with irritable bowel syndrome.

Forbes JD, et al. One of the biggest culprits of chronic inflammation is a poor diet. Consuming a lot of processed foods, sugar, and unhealthy fats can trigger an inflammatory response in the body. Other factors that may cause chronic inflammation include smoking, lack of sleep, and prolonged stress.

To reduce inflammation and support your longevity, focus on eating whole, nutrient-dense foods. Prioritize healthy fats such as omega-3s found in fish and nuts. Regular exercise, stress-reduction techniques such as meditation, and plenty of sleep can also help combat inflammation.

Interestingly, a healthy gut microbiome may play a crucial role in reducing inflammation. Studies have shown that certain gut bacteria can produce anti-inflammatory compounds that may help protect the body from chronic inflammation.

Conversely, an imbalance in gut bacteria known as dysbiosis may promote inflammation. Additionally, probiotics may help balance the gut microbiome and reduce inflammation. Consult with your healthcare provider to determine if a probiotic supplement is right for you.

Other lifestyle factors that can impact longevity include maintaining a healthy weight, not smoking, drinking alcohol in moderation, and staying physically active. Prioritizing gut health, reducing inflammation, and focusing on healthy habits can all help us live longer, healthier lives.

By prioritizing our gut health, reducing inflammation, and making healthy lifestyle choices, we can support our longevity and add years to our lifespan. While it may require a few lifestyle changes, investing in our health is always worth it in the long run.

So start small, make changes one at a time, and get on the path to a longer, healthier life. As a Lyme literate physician, Dr Muran has been treating Lyme recovery for 15 years collaborating with Drs.

Ray Jones, Ray Stricker, Joseph Jemsek and Richard Horowitz. As appears in Insights into Lyme Disease Treatment, the functional medicine approach uncovers the reasons for prior failures in treatment.

Healthy longevity: The role of the gut microbiome k The effects of polyphenols and other bioactives on human health. LDSC regression analysis is a new method for estimating genetic correlation, which requires only GWAS summary statistics. Gut microbiota may be a pathogenic factor of colorectal cancer CRC , and Veillonella has been found to contribute to CRC in humans [ 54 ]. Competing interests The authors state that they have no competing interests. Suppose the genetic instruments used are associated with the exposure rather than with any confounders of the exposure-outcome relationship.
Study Links Gut Health and Longevity | Thorne Gut health and longevity : 28 April Gut health and longevity accessed February 13, Anv BMJ. Orwoll, Hralth D. Consuming a lot of processed Immune system fortification, sugar, and unhealthy fats can trigger an inflammatory response in the body. Plus, those with less diverse gut environments used more medications and were nearly twice as likely to die during the study period. Please enable JavaScript in your browser to complete this form.
Gut microbiome implicated in healthy aging and longevity | ScienceDaily He, D. Nat Aging. Recent research may hold clues to the answer. Bulsiewicz notes. Tan J, et al. Learn Nutrition Gut Health COVID Healthy Living Life Stages Health Conditions Podcasts. Digestive Health Healthy Aging Nutrition.
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In her current research she hopes to identify novel mechanisms of gut-host interactions and help develop therapeutics to treat age-related declines in health. She has a secondary appointment in the Department of Molecular Genetics and Microbiology and is on the team at the Duke Microbiome Center and the Duke Aging Center , where she is a senior fellow.

She works with a team of graduate students, postdocs, and staff members in the department to promote diversity in hiring, community outreach, and mentoring initiatives. After moving from China to Los Angeles as a child, mentoring played a role in Han's development, and she has paid it forward by teaching at underserved public schools and led a summer program for underrepresented minority students at Stanford.

Her interest in science, she said, has evolved over time, starting with a fascination with bugs in her childhood and then to yeast genetics as an undergraduate at the Massachusetts Institute of Technology. Gut Microbiome May Hold the Key to Healthy Aging.

Cite This Page : MLA APA Chicago Institute for Systems Biology. ScienceDaily, 18 February Institute for Systems Biology. Gut microbiome implicated in healthy aging and longevity. Retrieved February 13, from www. htm accessed February 13, Explore More.

Race-Based Variations in Gut Bacteria Emerge by 3 Months of Age. One of the systems that is vulnerable to external influence is the gut microbiome. Our Genes Shape Our Gut Bacteria, New Research Shows.

July 8, — Researchers discovered that most bacteria in the gut microbiome are heritable after looking at more than 16, gut microbiome profiles collected over 14 years from a long-studied population of Study Suggests That Gut Fungi Are Not Associated With Parkinson's Disease.

In this novel study a team of investigators Could Boosting the Gut Microbiome Be the Secret to Healthier Older Age? June 4, — Fecal transplants from young to aged mice can stimulate the gut microbiome and revive the gut immune system, a study by immunologists has shown.

The study suggest that the gut microbiome could be a Print Email Share. Trending Topics. Breast Cancer. Immune System. Medical Devices. Child Development. Healthy Aging. Smart Earrings Can Monitor a Person's Temperature. Researchers 3D-Print Functional Human Brain Tissue. Fermented foods such as kimchi, sauerkraut, and kefir are great sources of gut-healthy probiotics.

Additionally, consuming plenty of fruits, vegetables, and whole grains can provide the nutrients that support a thriving microbiome. By taking care of your gut, you just may be adding years to your life.

However, when inflammation becomes chronic, it can put our health at risk. Long-term inflammation has been linked to a wide range of health concerns, from joint pain to heart disease.

According to a recent study, chronic inflammation may even lower your life expectancy. One of the biggest culprits of chronic inflammation is a poor diet. Consuming a lot of processed foods, sugar, and unhealthy fats can trigger an inflammatory response in the body.

Other factors that may cause chronic inflammation include smoking, lack of sleep, and prolonged stress. To reduce inflammation and support your longevity, focus on eating whole, nutrient-dense foods.

Prioritize healthy fats such as omega-3s found in fish and nuts. Regular exercise, stress-reduction techniques such as meditation, and plenty of sleep can also help combat inflammation.

Interestingly, a healthy gut microbiome may play a crucial role in reducing inflammation. Studies have shown that certain gut bacteria can produce anti-inflammatory compounds that may help protect the body from chronic inflammation. Conversely, an imbalance in gut bacteria known as dysbiosis may promote inflammation.

Additionally, probiotics may help balance the gut microbiome and reduce inflammation. Consult with your healthcare provider to determine if a probiotic supplement is right for you. Other lifestyle factors that can impact longevity include maintaining a healthy weight, not smoking, drinking alcohol in moderation, and staying physically active.

Prioritizing gut health, reducing inflammation, and focusing on healthy habits can all help us live longer, healthier lives.

Gut health and longevity

Gut health and longevity -

After further analysis, they found that centenarians had more diverse gut bacteria and viromes than their younger counterparts. They also had higher levels of gut bacteria and viruses.

High microbial diversity is usually associated with a healthy gut microbiome. Infants tend to have high levels of actively replicating viruses that soon become dormant as they transition into adulthood.

However, the researchers found that centenarians had higher levels of actively replicating viruses than younger adults — although not quite as many as infants.

The increased virome activity and diversity in centenarian microbiomes, noted the researchers, went on to boost the metabolic capacity of bacteria, which is linked to health benefits. They noted, for example, that higher sulfur metabolism — as seen in the centenarians — is linked to increased protection against aerobic pathogens.

The viruses we found in the healthy Japanese centenarians contained extra genes that could boost the bacteria. Ulm noted that a diverse gut virome enhances the detoxification functions of gut bacteria. Ulm noted that the findings demonstrate the relationship between the gastrointestinal tract and the human liver, which removes toxic metabolic byproducts from our bodies via a complex array of systems.

MNT also spoke with Dr. He noted that one limitation is that the study provided little information about what gave rise to the healthful microflora and viromes in the study. If we are able to get these bacteria and their viruses to move in with the people who do not have them, more people could benefit from them.

And the crazy thing is that we can actually change the composition of intestinal bacteria. We cannot change the genes — at least not for a long time to come.

Should all viruses be considered villains? In this feature, we meet bacteriophages. These viruses live in us and on us and easily outnumber bacteria. In this Special Feature, we give an overview of the communities of microorganisms, called microbiota, that form a symbiotic whole with our human cells.

Bacteria, viruses, and fungi are integral to human health. Find out why their contribution is so important and how modern life threatens their…. Some fermented foods Buettner recommends consuming regularly that are widely accessible here in the States are sauerkraut, low-sugar yogurt, and tempeh.

Polyphenols are active compounds that help protect the body from harmful free radicals including ultraviolet rays, radiation, and some pathogens. According to Buettner, many of the foods popular in Blue Zones are great sources of it.

A few in particular include coffee, berries, nuts, spinach, and dark chocolate. There are many anti-inflammatory herbs linked to longevity , but Buettner highlights these specific ones because they have especially been scientifically proven to help rid the body of harmful bacteria.

Ginger and turmeric have become the ahem gold standard when it comes to warding off inflammation with herbs. Watch the video below to learn more about the health benefits of turmeric: .

So far, Buettner has highlighted several types of foods that are common in all five Blue Zones. But something they collectively don't eat much of is sugar. They don't replace it with chemical sugar substitutes like Splenda either.

Some reasons why honey makes the best sugar alternative is because it's antibacterial, antimicrobial, and high in antioxidants. Sugar on the other hand, is directly linked to killing the good bacteria in the gut. The great part about these gut health tips is that you don't have to live in a Blue Zone to put them to practice.

Upping your intake of whole grains, veggies, fruits, nuts, beans, and fermented foods is something you can do no matter where in the world you live. Ditto for using honey as your go-to sweetener and brushing your teeth.

Over time, these small habits have a big effect. One you'll likely be around to see pay off for many, many years. Oh hi!

Maintaining a diverse and healthy gut microbiome may positively influence your metabolism and weight regulation, which can contribute to overall health and longevity. Beneficial bacterial strains such as Akkermansia muciniphila have been associated with supporting GLP-1 production, a hormone produced in the gut that triggers a host of downstream metabolic effects including reducing appetite, helping to release insulin, and supporting a healthy weight.

Conversely, low levels of beneficial bacteria have been linked to metabolic disorders and obesity. Gut bacteria such as Anaerobutyricum hallii , Clostridium butyricum , and Clostridium beijerinckii can produce bioactive compounds such as short-chain fatty acids SCFAs , which have been associated with various health benefits.

SCFAs, for example, may contribute to the maintenance of intestinal health and have systemic effects on metabolism. Maintaining a healthy gut microbiome is crucial for proper digestion and can help prevent issues such as constipation, diarrhea, and other gastrointestinal problems that can increase and impact the quality of life as you age.

Aging is associated with a decrease in the diversity of the gut microbiota. And, of course, a more diverse microbiome is generally considered healthier.

Strategies to promote microbial diversity, such as a varied and fiber-rich diet, may have positive effects on gut health and, consequently, on the aging process. Of course, as mentioned above, one of the most obvious ways to improve gut health is by eating healthier.

Adopting a diet rich in fiber , fruits, vegetables, and fermented foods can nourish and support the growth of beneficial gut bacteria.

Probiotics and prebiotics, found in foods like yogurt, kefir, and sauerkraut, can also contribute to a flourishing gut microbiota. And right alongside a healthy diet sits exercise. Physical activity has been shown to positively influence the gut microbiota.

Regular exercise helps maintain a diverse and balanced microbial community, contributing to overall health and longevity. Chronic stress can negatively impact the gut microbiota, leading to imbalances. Practices such as meditation, deep breathing exercises, and mindfulness can help manage stress and support a healthy gut.

While antibiotics are crucial for treating infections, their overuse can disrupt the balance of gut bacteria.

The gut Antioxidant rich fruits is an lonyevity component of the body, but its importance in longfvity Gut health and longevity aging Gut health and longevity is unclear. ISB researchers and longevitu collaborators have identified distinct lobgevity in the gut microbiome that are associated with either healthy or unhealthy aging trajectories, which in turn predict survival in a population of older individuals. The work is set to be published in the journal Nature Metabolism. The research team analyzed gut microbiome, phenotypic and clinical data from over 9, people -- between the ages of 18 and years old -- across three independent cohorts. The team focused, in particular, on longitudinal data from a cohort of over community-dwelling older individuals years oldallowing them to track health and survival outcomes. The data showed that gut microbiomes became increasingly unique i.

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