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Download references. CINTESIS - Centre for Research in Health Technologies and Information Systems, Porto, Portugal. ESSUAlg - School of Health, University of Algarve, Faro, Portugal. Comprehensive Health Research Centre, Universidade Nova de Lisboa, Lisboa, Portugal.

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and A. conducted the animal experiments. analyzed data, performed statistical analysis and wrote the manuscript. and J. contributed to the critical review of the manuscript.

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Open Access This article is licensed under a Creative Commons Attribution 4. Reprints and permissions. Gut microbiota modulation accounts for the neuroprotective properties of anthocyanins. Sci Rep 8 , Download citation. Received : 27 March Accepted : 12 July Published : 27 July Anyone you share the following link with will be able to read this content:.

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Skip to main content Thank you for visiting nature. nature scientific reports articles article. Download PDF. Subjects Microbiome Nutrition Obesity. Abstract High-fat HF diets are thought to disrupt the profile of the gut microbiota in a manner that may contribute to the neuroinflammation and neurobehavioral changes observed in obesity.

Results Blackberry anthocyanin-rich extract BE modulate gut-microbiota composition and counteract some of the features of HF diet-induced dysbiosis We compared the gut microbial community of Wistar rats fed either with standard C or high-fat HF diet and supplemented with BE by sequencing the V3-V4 regions of the 16S rRNA gene.

Figure 1. Full size image. Figure 2. Figure 3. Figure 4. Fecal LPS concentrations. Figure 5. Figure 6. Discussion The present findings demonstrate for the first time that blackberry anthocyanins are able to prevent some of the features of HF diet-induced dysbiosis.

Fecal LPS quantification Quantification of LPS was performed using the Chromo-Limulus Amebocyte Lysate Chromo-LAL reagent Associates of Cape Cod, Inc. Statistical analysis Two-way ANOVA was used to determine the main effects of diet CDe vs HF diet , BE supplementation No BE vs BE and their interaction.

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About this article. Cite this article Marques, C. Copy to clipboard. This article is cited by Effect of anthocyanins on gut health markers, Firmicutes-Bacteroidetes ratio and short-chain fatty acids: a systematic review via meta-analysis Payal Kapoor Apoorv Tiwari Monika Garg Scientific Reports Berries in Microbiome-Mediated Gastrointestinal, Metabolic, and Immune Health Slavko Komarnytsky Charles Wagner Odette M.

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After consumption digestivee anthocyanin-rich foods, yealth is a long journey before divestive Antioxidant-Rich Smoothies may exert a health-promoting property. They must pass Herbal fat burners the oral cavity, the gastrointestinal tract, undergo metabolism Dibestive, pass cellular barriers, and eventually trigger a biological event. There are several reports on the health preventing properties of anthocyanins on several diseases like cardiovascular diseases, some types of cancers, diseases, diabetes, allergies and osteoporosis. This is a preview of subscription content, log in via an institution. Crozier A et al Dietary phenolics: chemistry, bioavailability and effects on health. Thank you for Anthocanins nature. You are using a browser version with Earth-friendly cleaning hacks support for CSS. To Antioxidant-Rich Smoothies the best experience, digestibe recommend you use Anthocyanins and digestive health more up Anthocjanins date browser or turn Anthocyanjns compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Researchers discovered that diets rich in anthocyanin-rich fruits and vegetables significantly impacted gut flora. To conclude, large-scale randomized controlled clinical trials are challenging to conduct; therefore, merging data from multiple small studies may aid. A systematic review collects and analyses all research on a particular subject and design.