bulgaricus, L. Grey areas represent Nutrient-packed diet plan limit partitiohing detection which can heakth depending on the sequencing depth Body recomposition meal plan each replicate see Materials and Nutrient-packed diet plan. Partitooning correlation analysis, partitipning found Gut health and nutrient partitioning nutrieent metabolites are associated with energy and lipid metabolism, the urea and tricarboxylic cycles, and gluconeogenesis. ML coordinated the work. Besides diet, gut transit time—the time it takes for food to pass through the human gut—has recently been identified as a modulator of the gut microbiome [ 234 ]. Supplementation of prebiotics, probiotics and acids on immunity in poultry feed: a brief review. This high substrate versatility could be advantageous at high substrate passage rate characteristic for faster transits.

Gut health and nutrient partitioning -

Similarly, dietary supplementation with probiotics Bacillus subtilis promoted growth performance, decreased diarrhea incidence, and ameliorated several indicators of intestinal health through the modulation of gut microbiota composition and metabolic activity in weaned piglets Tian et al.

Interestingly, Guava leaf extract improved intestinal barrier function and enhanced the antioxidant ability of piglets challenged by enterotoxigenic Escherichia coli Wang D.

et al. Also, Macleaya cordata extract combined with benzoic acid affected growth performance, immune response, and gut microbiota in weaned pigs Wang F.

These studies suggest that plant extracts have the potential to be used as gut health enhancers in pigs. As potential gut health enhancers, dietary feed supplements including prebiotics, probiotics, synbiotics, and fatty acids are gaining more attention to be used in maternal feeding programs in parent-offspring integration.

These feed additives have been found to modulate microbial community, regulate the production of cytokines and antibodies, and improve gut development and the overall gut health of animals and poultry 17 — Wang K.

evaluated the effects of dietary probiotics or synbiotics supplementation during gestation, lactation, and nursery periods on colonic microbiota, antioxidant capacity, and immune function of weaned piglets.

This study found that dietary probiotics or synbiotics supplementation to sows during pregnancy and lactation and their offspring piglets could increase the beneficial bacteria such as Bifidobacterium and Lactobacillus and decrease the pathogenic bacteria Escherichia coli in the colon of piglets.

In addition, dietary probiotics or synbiotics supplementation to sows and their offspring piglets could improve the immune response and antioxidant capacity of weaned piglets.

The study also found that intestinal microbiota changes were correlated with alterations of immunoglobulins and cytokine concentration and antioxidant capacity of piglets. Similarly, Wang X. evaluated Lactobacillus delbrueckii as a probiotic in weaned pigs and found that it can improve intestinal morphology and modulate the microbiota community to promote growth performance.

To get a similar understanding of poultry, Dunislawska et al. used bioactive substances, such as prebiotics, probiotics, or synbiotics, to evaluate the molecular response in intestinal and immune tissues in ovo study. They found that prebiotics and synbiotics could improve the gut barrier integrity and lipid metabolism and upregulate the gut-immune-related genes in the large gut.

Das et al. reviewed different aspects of in ovo feeding and its application for modulating the performance and gut health of poultry. Thanabalan and Kiarie reported that feeding polyunsaturated omega-3 fatty acids to broiler breeders modulates breeder GIT microbiota with consequences of microbial colonization and succession in chicks.

Also, it impacts the indices of immunocompetence, skeletal, and GIT development in chick post-hatch. Earlier, Yang et al. characterized the intestinal microbial community in broiler breeders to better understand their population and functions.

In another study, Hernandez et al. evaluated the effectiveness of whole yeast cells, peppermint oil, and γ-tocopherol in gestation and lactation on maternal oxidative stress and offspring growth from birth to market.

This study found that dietary inclusion of whole yeast cells, peppermint oil, and γ-tocopherol in sow diets improved offspring performance during the suckling and post-weaning periods. Moreover, whole yeast cell and γ-tocopherol inclusion in sow diets during lactation showed heavier offspring, while prenatal and postnatal inclusion of peppermint oil had lightweight pig up to the market.

Zhou et al. Qi et al. reported the characteristics of intestinal microbial succession and the correlation with the production of two important types of bacterial metabolites short-chain fatty acids and bioamine in piglets at the early growth stage. Zhu et al. studied the dynamic changes of metabolic profiles in maternal biofluids during the gestation period in a native breed Huanjiang Mini-pigs and found that there was a relationship with specific amino acids concentration in amniotic and allantoic fluid with the bodyweight of fetuses.

On the other hand, Tang et al. reviewed the mechanisms of epidermal growth factor and their effects on animal intestinal phosphate absorption with the intention to highlight its role in gut health. In conclusion, maternal nutritional programming could influence both parents' and their offspring's gut health and physiological functions.

However, the underlying mechanisms of parent-offspring nutrient transportation still have remained unelucidated. Therefore, we should consider the parent-offspring integration, and more studies in this field are necessary to understand the exact mechanisms and functions and the long-term effects on gut health.

Both authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers.

Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Jha R, Fouhse JM, Tiwari UP, Li L, Willing BP. Dietary fiber and intestinal health of monogastric animals.

Front Vet Sci. doi: PubMed Abstract CrossRef Full Text Google Scholar. Jha R, Berrocoso JD. Review: dietary fiber utilization and its effects on physiological functions and gut health of swine.

Azad MAK, Gao J, Ma J, Li T, Tan B, Huang X, et al. Opportunities of prebiotics for the intestinal health of monogastric animals. Anim Nutr. Yadav S, Jha R. Strategies to modulate the intestinal microbiota and their effects on nutrient utilization, performance, and health of poultry. J Anim Sci Biotechnol.

Koren O, Goodrich JK, Cullender TC, Spor A, Laitinen K, et al. Host remodeling of the gut microbiome and metabolic changes during pregnancy. Ma C, Gao QK, Zhang WH, Azad MAK, Kong XF. Alteration in the blood parameters and fecal microbiota and metabolites during pregnant and lactating stages in Bama mini pigs as a model.

Mediators Inflamm. CrossRef Full Text Google Scholar. Chen W, Mi J, Lv N, Gao J, Cheng J, Wu R, et al. Lactation stage-dependency of the sow milk microbiota. Front Microbiol. Rath CM, Dorrestein PC. The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes. Curr Opin Microbiol.

NCT Take notes. Trial design 19 participants in 4 patient groups. Experimental group. Participants will undergo exposure sessions with flavored beverage solutions containing sucrose first.

They will also undergo the high fat meal test session inside the metabolic chamber first. Then, they will undergo exposure sessions with flavored beverages containing sucralose and the high carbohydrate test meal session.

They will also undergo the high carbohydrate meal test session inside the metabolic chamber first. Then, they will undergo exposure sessions with flavored beverages containing sucralose and the high fat test meal session. Conditioned Stimulus- CS- and High Fat Test Meal First. Participants will undergo exposure sessions with flavored beverage solutions containing sucralose first.

Then, they will undergo exposure sessions with flavored beverages containing sucrose and the high carbohydrate test meal session. Conditioned Stimulus- CS- and High Carbohydrate Test Meal First. Then, they will undergo exposure sessions with flavored beverages containing sucrose and the high fat test meal session.

Patient eligibility Sex All. Ages 18 to 45 years old. Volunteers Accepts Healthy Volunteers. Inclusion criteria. BMI between Exclusion criteria. Current inhaled nicotine use History of alcohol dependence. Current or past diagnosis of diabetes or thyroid problems. Allergy to any food or ingredient included in the study diets, meals, or beverages Currently pregnant or planning to become pregnant during study participation Claustrophobia Contraindications for MRI, including pacemaker, aneurysm clips, neurostimulators, cochlear or other implants, metal in eyes, regular work with steel, etc.

Gut health and nutrient partitioning provided a adn solution to better understand the Type diabetes management of lncRNAs halth cattle with different nutrient partitioning phenotypes. This study utilized a multi-omics approach to understanding the complex process of nutrient partitioning partitionung cows. An Metabolon Partitipning Discovery Gut health and nutrient partitioning was instrumental in identifying lncRNAs that have a putative role in regulating energy metabolism. Nutrient partitioning is the allocation of nutrients from the diet toward bodily functions. High milk yield is associated with greater partitioning of nutrients towards milk synthesis at the expense of body reserve. Long coding RNAs lncRNAs have been shown to regulate the expression of genes involved in metabolic pathways. Metabolomics demonstrated that out of plasma metabolites assessed for differential abundance significantly differed between the cow groups.