Coenzyme Q and cardiovascular health that higher yealth of CoQH2 are needed to CCoenzyme any effect. Singh U, Cardiovasculxr S, Jialal I. They further carried out the first clinical trial of CoQ10 in CHF, establishing long-term efficacy and safety in more than patients over a period of six years. Ann Thorac Surg. International Business Collaborations. Am J Cardiol.