Supplemenys info nccih. Antioxidant supplements Lifestyle. In addition to improving heart health and cognitive function, some research suggests that antioxidants could aid in the prevention of type 2 diabetes.

Antioxidant supplements -

In fact, when the trials with low risks of bias were considered separately, the increased mortality was even more pronounced 1. The potential damage from vitamin A disappeared when only the low risks of bias trials were considered. The increased risk of mortality was associated with beta-carotene and possibly vitamin E and vitamin A, but was not associated with the use of vitamin C or selenium.

The current evidence does not support the use of antioxidant supplements in the general population or in patients with various diseases. We found no evidence to support antioxidant supplements for primary or secondary prevention. Beta-carotene and vitamin E seem to increase mortality, and so may higher doses of vitamin A.

Antioxidant supplements need to be considered as medicinal products and should undergo sufficient evaluation before marketing. Our systematic review has demonstrated that antioxidant supplements may increase mortality.

We have now updated this review. To assess the beneficial and harmful effects of antioxidant supplements for prevention of mortality in adults. We searched The Cochrane Library , MEDLINE, EMBASE, LILACS, the Science Citation Index Expanded, and Conference Proceedings Citation Index-Science to February We scanned bibliographies of relevant publications and asked pharmaceutical companies for additional trials.

We included all primary and secondary prevention randomised clinical trials on antioxidant supplements beta-carotene, vitamin A, vitamin C, vitamin E, and selenium versus placebo or no intervention.

Three authors extracted data. Random-effects and fixed-effect model meta-analyses were conducted. Risk of bias was considered in order to minimise the risk of systematic errors.

Trial sequential analyses were conducted to minimise the risk of random errors. Back to top. Get to Know Us. Make Money with Us. Amazon Payment Products. Let Us Help You. Conditions of Use Privacy Notice Your Ads Privacy Choices © , Amazon.

com, Inc. or its affiliates. Amazon Music Stream millions of songs. Amazon Ads Reach customers wherever they spend their time. Fifty-two trials included 80, participants with various diseases in a stable phase including gastrointestinal, cardiovascular, neurological, ocular, dermatological, rheumatoid, renal, endocrinological, or unspecified diseases.

A total of 21, of , participants The trials appeared to have enough statistical similarity that they could be combined. When all of the trials were combined, antioxidants may or may not have increased mortality depending on which statistical combination method was employed; the analysis that is typically used when similarity is present demonstrated that antioxidant use did slightly increase mortality that is, the patients consuming the antioxidants were 1.

In fact, when the trials with low risks of bias were considered separately, the increased mortality was even more pronounced 1. The potential damage from vitamin A disappeared when only the low risks of bias trials were considered. The increased risk of mortality was associated with beta-carotene and possibly vitamin E and vitamin A, but was not associated with the use of vitamin C or selenium.

The current evidence does not support the use of antioxidant supplements in the general population or in patients with various diseases. We found no evidence to support antioxidant supplements for primary or secondary prevention.

Beta-carotene and vitamin E seem to increase mortality, and so may higher doses of vitamin A. Antioxidant supplements need to be considered as medicinal products and should undergo sufficient evaluation before marketing.

Our systematic review has demonstrated that antioxidant supplements may increase mortality. We have now updated this review. To assess the beneficial and harmful effects of antioxidant supplements for prevention of mortality in adults.

We searched The Cochrane Library , MEDLINE, EMBASE, LILACS, the Science Citation Index Expanded, and Conference Proceedings Citation Index-Science to February We scanned bibliographies of relevant publications and asked pharmaceutical companies for additional trials.

We included all primary and secondary prevention randomised clinical trials on antioxidant supplements beta-carotene, vitamin A, vitamin C, vitamin E, and selenium versus placebo or no intervention.

Every Antioxifant of us has Antioxidant supplements free radicals Antioxidant supplements antioxidants Antioxidant supplements inside of our Supplemwnts at all times. Some Boost energy at work are made from the body itself, suppllements Antioxidant supplements must get others from our Anioxidant by eating suplpements foods that double as anti-inflammatory foods. Our bodies also produce free radicals as byproducts of cellular reactions. For example, the liver produces and uses free radicals to detoxify the body, while white blood cells send free radicals to destroy bacteria, viruses and damaged cells. When antioxidant levels in the body are lower than that of free radicals — due to poor nutrition, toxin exposure or other factors — oxidation wreaks havoc in the body. The effect? Official websites use. Antioxidant supplements A. gov website belongs to an suppelments government organization in Antioxidant supplements United States. gov website. Share sensitive information only on official, secure websites. Antioxidants are man-made or natural substances that may prevent or delay some types of cell damage.