Visceral fat and cardiovascular health -
Some of your belly fat, called subcutaneous fat, lies just beneath your skin. As you gain weight and more fat accumulates in your belly, you develop another type called visceral fat.
Visceral belly fat poses a unique danger to your health. This fat goes deep into your abdomen, wrapping around organs such as your heart, blood vessels, liver, kidneys, and intestines.
Your visceral fat contains many different cells. Some cells store fat, while others release active substances that cause inflammation. Inflammation travels throughout your body, contributing to conditions that lead to cardiovascular disease, such as high blood pressure, high blood lipids cholesterol and other fats , and Type 2 diabetes.
Visceral fat also has a direct impact because it surrounds your heart and blood vessels. As a result, its inflammatory substances accelerate diseases like atherosclerosis fatty plaque in your arteries. The fat around your heart pericardial fat easily sends substances into your coronary blood vessels, raising your chances of developing coronary artery disease.
Too much pericardial fat also significantly increases your risk of developing heart failure and atrial fibrillation. Additionally, visceral fat puts you at a much higher risk of having a heart attack. You need diagnostic imaging to determine the exact amount of visceral fat in your body.
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Download references. We thank the engineers of Xiuzheng Yue from Philips Healthcare, Beijing, China, for his skilled assistance during the image scanning and postprocessing, and thank Dr. Min Zhao from the Department of Pharmaceutical Diagnostics, GE Healthcare, Beijing, China, for her help in statistical analysis of this article.
This work was supported by the fourth affiliated hospital of Harbin medical university special fund research projects Grant NO. HYDSYTB , the Beijing Cihua Medical Development Foundation Project Research on CT-assisted diagnosis of coronary heart disease based on artifcial intelligence , the important research and development projects in heilongjiang province Grant NO.
Department of Radiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China. You can also search for this author in PubMed Google Scholar. WW, TZ, JB designed the study. CG, ZS were responsible for the recruitment of subjects and acquisition of data.
XL, HP, SW performed the experiments and analyzed the data. JB contributed to drafting the manuscript. MZ contributed to statistical analysis of data. XY contributed to setting of scanning sequence of magnetic resonance imaging.
JS contributed to figure and table typesetting. All authors read and approved the final manuscript. Correspondence to Tong Zhang. This study was approved by our Institutional Review Board.
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Reprints and permissions. Bai, J. et al. Correlation analysis of the abdominal visceral fat area with the structure and function of the heart and liver in obesity: a prospective magnetic resonance imaging study.
Cardiovasc Diabetol 22 , Download citation. Received : 08 June Accepted : 19 July Published : 10 August Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative.
Skip to main content. Search all BMC articles Search. Download PDF. Download ePub. Abstract Background The differences in fat deposition sites exhibit varying degrees of systemic inflammatory responses and organ damage, especially in obese individuals with excessive visceral fat.
Objective Clarifying the differences in and correlations of heart and liver indicators among groups with different severities of AVFA by magnetic resonance imaging MRI. Methods Sixty-nine subjects with obesity were enrolled.
Results In the study group, the incidences of type 2 diabetes mellitus T2DM and insulin resistance were higher, and liver function indicators were worse. Conclusion The high AVFA group had a larger LVM, GPWT and PATV, more obvious changes in LVER, impaired left ventricular diastolic function, an increased risk of heart disease, and more severe hepatic fat deposition and liver injury.
Introduction Individuals with obesity have different degrees of body fat distribution, metabolic characteristics, and related heart and liver damage.
Methods Participants From September to April , 69 subjects with obesity were recruited from the Weight Loss and Metabolic Surgery Department of the Fourth Affiliated Hospital of Harbin Medical University. Table 1 Clinical baseline characteristics Full size table.
Flowchart showing the inclusion and exclusion criteria for the study population. Full size image. Results The average age of the 69 participants who were finally enrolled was Table 2 MRI measurement results of the heart and abdomen Full size table. Table 3 Associations between AVFA and cardiac and abdominal MRI results by multivariable linear regression Full size table.
Discussion This study included 69 subjects with obesity who were not obese due to abnormal hormone levels. Limitations Previous studies mostly used echocardiography to evaluate heart and liver function. Conclusion In patients with severe obesity, a significant increase in the AVFA is characterized by changes in LVER.
Availability of data and materials The datasets generated and analyzed during the current study are available from the corresponding authors on reasonable request. Abbreviations ABSI: A body shape index ALT: Alanine aminotransferase AST: Aspartate aminotransferase ASFA: Abdominal subcutaneous fat area AVFA: Abdominal visceral fat area BMI: Body mass index BSA: Body surface area CVAI: Chinese visceral adiposity index CV: Cardiovascular FOV: Field of view GCS: Global circumferential strain GLS: Global longitudinal strain GRS: Global radial strain GPWT: Global peak wall thickness GGT: Gamma-glutamyl transferase HOMA-IR: Homeostasis model assessment of insulin resistance HF: Heart failure LVER: Left ventricular eccentricity ratio LVM: Left ventricular mass MRI: Magnetic resonance imaging NAFLD: Nonalcoholic fatty liver disease NASH: Nonalcoholic steatohepatitis NFS: NAFLD fibrosis score PATV: Pericardiac adipose tissue volume PDFF: Proton density fat fraction SAT: Subcutaneous adipose tissue T2DM: Type 2 diabetes mellitus VAT: Visceral adipose tissue.
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As well as being the first study to find that secondary prevention treatment has no effect on recurrent risk if abdominal obesity is present, the research is also the first to analyze by sex. When examined separately, males and females demonstrated certain differences. The link between waist circumference and subsequent heart attacks was stronger in men, for example.
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Potential carsiovascular of interest. Cooking classes and workshops the Heart health herbal extracts caridovascular Visceral fat and cardiovascular health Cardiovvascular Sciences Research Scholars award. has received research funding from KOWA, Gilead, ViiV, and Theratechnologies; has received consulting fees from Theratechnologies and ViiV; and is a member of the scientific advisory board of Marathon Asset Management, all unrelated to the present work. All other authors report no potential conflicts. Persons with well-treated human immunodeficiency virus HIV demonstrate a 2-fold higher risk of cardiovascular disease CVDwhich may be related to excess visceral adipose tissue VAT. 
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