Visceral fat and gut health -
In contrast, we found that the gut microbiota plays an important role in the beneficial effect of good nutrients, such as fibre or vitamin E.
We show that specific gut bacteria play an important role in linking certain beneficial nutrients to less belly fat. Diet alone did not have a strong impact on the observed links between gut microbes and belly fat, as specific gut bacteria were linked to belly fat accumulation regardless of diet.
This confirms what was previously seen in mice, that gut microbiota alone could affect fat accumulation. Our findings also provide further evidence that the human gut microbiota plays an important role in the individualised response to food.
A limitation of our study was that we analysed measurements taken at a single point in time. This means that we cannot establish causal links. Another drawback is that most people misreport what they eat. Researchers are working on improving the way that diet is reported, which should lead to more accurate work in the future.
Our results mean that in the future, you may need to have your gut microbiota checked so that your doctor or dietitian can give you personalised dietary advice. Although bacteria may be partially to blame for the rise in rates of obesity, until we know more it is best to stick to a healthy, varied diet rich in fibre, fruit and vegetables, which in turn may result in a healthier gut microbiota.
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Public Health Nutr. Download references. This work was supported by JST, Center of Innovation Program COI , and Kao Co. Tokyo, Japan. The stability test for the gut microbiota was conducted at TechnoSuruga Laboratory Co. Department of Active Life Promotion Sciences, Graduate School of Medicine, Hirosaki University, Aomori, Japan.
Health Care Food Research Laboratories, Kao Corporation, Tokyo, Japan. Biological Science Research Laboratories, Kao Corporation, Tokyo, Japan. Department of Social Medicine, Graduate School of Medicine, Hirosaki University, Aomori, Japan.
Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan. Health Intelligence Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan. You can also search for this author in PubMed Google Scholar. analysed and interpreted the data.
and S. designed the analyses and contributed to the manuscript. contributed to the data acquisition. contributed to the data interpretation. is the guarantor of this work and takes responsibility for the integrity and accuracy of the data.
All authors reviewed and edited the manuscript and approved the final version of the manuscript. Correspondence to Shigeyuki Nakaji.
Authors N. were employed by Kao Corporation Tokyo, Japan. All other authors declare no competing interests.
There are no patents, products in development or marketed products to declare. Open Access This article is licensed under a Creative Commons Attribution 4. Reprints and permissions.
Ozato, N. Blautia genus associated with visceral fat accumulation in adults 20—76 years of age. npj Biofilms Microbiomes 5 , 28 Download citation. Received : 04 March Accepted : 12 September Published : 04 October Anyone you share the following link with will be able to read this content:.
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Abstract The gut microbiota is reported to be related to obesity, and visceral fat is reported to be strongly associated with cardiovascular disease and overall mortality. Introduction The gut microbiota is highly involved in host energy regulation and homoeostasis, thereby contributing to diabetes and obesity status.
Results Characteristics of participants As a previous study reported a significant difference in the gut microbiota between men and women, 31 the participants were divided into two groups stratified by sex.
Table 1 Participant characteristics stratified by sex Full size table. Full size image. Table 2 Association of the relative abundance of the human gut microbial genera and VFA in men and women Full size table. Table 3 Association between VFA and relative abundance of a microbial genus Blautia and Bifidobacterium adjusted by Models 1—3 Full size table.
Table 4 Association between BMI and relative abundance of a microbial genus Blautia and Bifidobacterium adjusted by Models 1—3 Full size table. Discussion This study reports a sex-dependent association between VFA and the gut microbiota in a relatively large number of participants Japanese individuals.
Methods Design, participants, and ethics The Iwaki Health Promotion Project was launched in as an annual health check-up for local residents, aiming to prolong a healthy lifespan. Measurements of the gut microbiota Faecal samples from each participant were collected using a commercial tube kit TechnoSuruga Laboratory Co.
Reporting Summary Further information on research design is available in the Nature Research Reporting Summary linked to this article. Data availability All data generated during and analysed during the current study are included in this article and its Supplementary information files, or are available from the corresponding author upon reasonable request.
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Compared with the Viscral benign effects of increased subcutaneous adipose tissue SATincreased Visveral adipose tissue VAT volume is Viscceral causal risk factor for hypertension, hyperlipidemia, Natural remedies for headaches 2 diabetes, and cardiovascular disease. Visceal rodents, increased VAT Post-workout meal timing strategies and Visceral fat and gut health Vjsceral and heath lipid accumulation in kidneys and liver have been induced by alterations in the gut microbiome. However, few studies have characterized these relationships in humans. To evaluate the tissue triglyceride content of VAT and SAT, liver, kidneys, and pancreas in male and female adults and assess associations with markers of glucose tolerance, serum insulin, and lipids and characteristics of the gut microbiome. Body mass index BMIbody composition, and oral glucose tolerance were assessed. Microbiome analysis was conducted on stool samples using 16S rRNA v3 amplicon sequencing. Thank you for visiting Heapth. You Vusceral using a browser version with limited support for CSS. To obtain Viscefal best experience, Satiety effect of chewing recommend you Healthh a more up to Viscral browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. The gut microbiota is reported to be related to obesity, and visceral fat is reported to be strongly associated with cardiovascular disease and overall mortality. However, the association between the gut microbiota and obesity has mainly been studied using body mass index BMI as a proxy for obesity.
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